Weinberg marc (74 risultati)
Uncanny Spectacle: the Public Career of John Singer Sargent
[Sargeant, John Singer] Simpson, Marc With Richard Ormond & H Barbara Weinberg
- Brossura
Da: Lorrin Wong, Bookseller, Los Angeles, CA, U.S.A.Lorrin Wong, Bookseller
Contatta il venditoreVenditore con 1 stelleCondizione: Usato
EUR 11,09
EUR 5,17 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
1st printing of 1st edition. 192 pages, illustrated. Light diagonal crease on front wrapper (cover) otherwise a clean, unmarked, complete near fine trade paperback in decorative wrappers (soft cover book).
Altre immagini- Brossura
Da: Mullen Books, ABAA, Marietta, PA, U.S.A.Mullen Books, ABAA
Contatta il venditoreVenditore con 4 stelleCondizione: Usato
EUR 8,87
EUR 11,19 spedizioneSpedito in U.S.A.Quantità: 2 disponibili
Softcover. Condizione: VG/VG As New copy. Black wraps. xiii, 192 pp. 35 color plates. This is a softcover book. Published in conjunction with an exhibition held at the Sterling and Francine Clark Art Institute from June 15 to Sept. 7, 1997. Includes an annotated and illustrated catalogue of 35 works. Contents as follows: Forewor…d / Michael Conforti -- Introduction / Richard Ormond -- Sargent and Carolus-Duran / H. Barbara Weinberg -- Sargent and His Critics / Marc Simpson -- Catalogue / Marc Simpson. hing and Experimentation, 1877-1880. "Away for Venice," 1880-1882. "Crispation de Nerfs" 1880-1887. Appendix: Sargent's Exhibition History, 1877-1887. This book explores how the young American painter in just over a decade jumped from apprenticeship to wide acclaim, how he presented himself and his works, and how he sought to shape public perception of his talent. The book includes illustrations of almost every painting Sargent exhibited in Paris, London, and New York through 1887. Drawing on the correspondence of the artist, his friends, and his family, as well as an extensive review of contemporary critical responses, the text examines these works of Sargent's early maturity - some not exhibited in this century and others among his best-known work, including Carnation, Lily, Lily, Rose and Madame X. The authors contend the canvases present a fresh view of Sargent's aspirations and ambitions, representing a metaphoric self-portrait of the artist as a young man. The early paintings, their relationship to one another, and their reception also shed light on the complex, cosmopolitan art world in which Sargent lived.
- Brossura
Da: Mullen Books, ABAA, Marietta, PA, U.S.A.Mullen Books, ABAA
Contatta il venditoreVenditore con 4 stelleCondizione: Usato
EUR 8,87
EUR 11,19 spedizioneSpedito in U.S.A.Quantità: 2 disponibili
Softcover. Black wraps. xiii, 192 pp. 35 color plates. This is a softcover book. Published in conjunction with an exhibition held at the Sterling and Francine Clark Art Institute from June 15 to Sept. 7, 1997. Includes an annotated and illustrated catalogue of 35 works. Contents as follows: Foreword / Michael Conforti -- Introdu…ction / Richard Ormond -- Sargent and Carolus-Duran / H. Barbara Weinberg -- Sargent and His Critics / Marc Simpson -- Catalogue / Marc Simpson. hing and Experimentation, 1877-1880. "Away for Venice," 1880-1882. "Crispation de Nerfs" 1880-1887. Appendix: Sargent's Exhibition History, 1877-1887. This book explores how the young American painter in just over a decade jumped from apprenticeship to wide acclaim, how he presented himself and his works, and how he sought to shape public perception of his talent. The book includes illustrations of almost every painting Sargent exhibited in Paris, London, and New York through 1887. Drawing on the correspondence of the artist, his friends, and his family, as well as an extensive review of contemporary critical responses, the text examines these works of Sargent's early maturity - some not exhibited in this century and others among his best-known work, including Carnation, Lily, Lily, Rose and Madame X. The authors contend the canvases present a fresh view of Sargent's aspirations and ambitions, representing a metaphoric self-portrait of the artist as a young man. The early paintings, their relationship to one another, and their reception also shed light on the complex, cosmopolitan art world in which Sargent lived. VG (May have marks from previous gallery owner.).
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Marc Simpson, John Singer Sargent, Richard Ormond, H. Barbara Weinberg
- Brossura
- Prima edizione
Da: Dunaway Books, St. Louis, MO, U.S.A.Dunaway Books
Contatta il venditoreVenditore con 4 stelleCondizione: Usato - Quasi ottimo
EUR 17,74
EUR 3,44 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Paper Back. Condizione: Near Fine. Condizione sovraccoperta: Near Fine. First Edition. First printing. Light rubbing to the lower right corner. Light scuffing to the front cover. Otherwise in excellent condition. Pages are clean and bright with no markings.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Marc Simpson; John Singer Sargent; Richard Ormond; H. Barbara Weinberg; Sterling and Francine Clark Art Institute
- Brossura
Da: G.J. Askins Bookseller, New Lebanon, NY, U.S.A.G.J. Askins Bookseller
Contatta il venditoreVenditore con 5 stelleMembro dell’associazione: SNEAB
Condizione: Usato - Molto buono
EUR 17,74
EUR 5,17 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Very Good. 192 page paperback with several essay contributors and illustrations. At rear is large notes section, and Appendix with Sargent's Exhibition History. Unmarked, tight and clean.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Simpson, Marc, with Ormond, Richard and Weinberg, H. Barbara
Lingua: Inglese
Editore: Yale University Press/Sterling and Francine Clark Art Institute, New Haven and London/Williamstown, MA, 1997
- Brossura
- Prima edizione
Da: Saucony Book Shop, Kutztown, PA, U.S.A.Saucony Book Shop
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Quasi ottimo
EUR 17,74
EUR 5,17 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Soft cover. Condizione: Near Fine. 1st Edition. Stiff color illus. wraps. Slight shelf wear, virtually as issued. xiv,192 pp., 26 color plates, 36 b&w figures in text. Size: 4to - over 9¾" - 12" tall. Sargent, John Singer (illustratore). Book.
- Brossura
Da: Wonder Book, Frederick, MD, U.S.A.Wonder Book
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Buono
EUR 26,57
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Condizione: Good. Good condition. A copy that has been read but remains intact. May contain markings such as bookplates, stamps, limited notes and highlighting, or a few light stains.
- Rilegato
Da: medimops, Berlin, Germaniamedimops
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Molto buono
EUR 9,95
EUR 10,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Condizione: very good. Gut/Very good: Buch bzw. Schutzumschlag mit wenigen Gebrauchsspuren an Einband, Schutzumschlag oder Seiten. / Describes a book or dust jacket that does show some signs of wear on either the binding, dust jacket or pages.
- Rilegato
Da: Michener & Rutledge Booksellers, Inc., Baldwin City, KS, U.S.A.Michener & Rutledge Booksellers, Inc.
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Molto buono
EUR 22,17
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Hardcover. Condizione: Very Good. Condizione sovraccoperta: Very Good. Text clean and tight; NOTE: additional postage may be necessary for international shipping; 8vo 8" - 9" tall; 208 pages.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Simpson, Marc; Sargent, John Singer; Ormond, Richard; Weinberg, H. Barbara; Sterling And Francine Clark Art Institute
- Brossura
- Prima edizione
Da: Bristlecone Books RMABA, Ridgway, CO, U.S.A.Bristlecone Books RMABA
Contatta il venditoreVenditore con 4 stelleMembro dell’associazione: RMABA
Condizione: Usato - Quasi ottimo
EUR 21,24
EUR 9,47 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Soft cover. Condizione: Near Fine. 1st Edition. Near fine large softcover. Illustrated wraps. 4to. 192pp. Illustrated. No names or markings to text. First edition with full number line. Art oversized.
Altre immaginiEditore: Portland, ME: Privately Printed, 1984, 1984
- Rilegato
- Prima edizione
Da: WellRead Books, Shamong, NJ, U.S.A.WellRead Books
Contatta il venditoreVenditore con 5 stelleMembro dell’associazione: IOBA
Condizione: Usato
EUR 17,74
EUR 6,89 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Aggiungi al carrello1st edition; 8vo. blue cloth covered boards, hardcover; 43 pages; walking through Lower East Side, Chinatown, the Ghetto and Lower Italy, a fine, clean, tight copy.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Marc Simpson; John Singer Sargent; Richard Ormond; H. Barbara Weinberg; Sterling and Francine Clark Art Institute
- Brossura
- Prima edizione
Da: monobooks, Waterford, MI, U.S.A.monobooks
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 44,35
EUR 3,87 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Soft cover. Condizione: New. No Jacket. 1st Edition. First edition 1997, first printing, numbers line starts with 1, printed on occasion of the exhibition at Clark Art Institute. Large softcover without DJ as issued. Condition new, square tight and clean book, spine not creased, sharp corners, no edgewear, no names no underlinin…gs no highlights no bent page corners, not a reminder. 4to, 192 pages, well illustrated, index.
Editore: Portland Maine: By Author, 1984, Portland Maine, 1984
- Prima edizione
Da: Open Door Books MABA, Bath, ME, U.S.A.Open Door Books MABA
Contatta il venditoreVenditore con 2 stelleMembro dell’associazione: MABA
Condizione: Usato - Molto buono
EUR 17,74
EUR 7,71 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloCondizione: Very Good. No Jacket. First Edition. Very Good/No Jacket. First Edition. Autobiography. slight tape mark front board, 43 pgs, frontis. Autobiography.
Altre immaginiRevista Vuelta. Año XXI. Junio de 1997. Número 247
Guillevic; Enrique Krauze; Gastón Baquero; Steven Weinberg; Lezek Kolakowski; Marc Fumaroli; Fernando Savater; Hugo Vidal; Adolfo Castañon; Teodoro González de León; Fabienne Bradu; Miguel Gomes; Nilo Palenzuela
Lingua: Spagnolo
Editore: Vuelta Editorial, México, 1997
- Brossura
- Prima edizione
Da: La Social. Galería y Libros, Barcelona, B, SpagnaLa Social. Galería y Libros
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Quasi ottimo
EUR 20,99
EUR 25,50 spedizioneSpedito da Spagna a U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloTapa blanda. Condizione: Muy bien. Primera edición. ISSN: 01851586. PRIMERA EDICIÓN. FIRST EDITION. Director: Octavio Paz. Contenido: Guillevic "Te excribo"; Enrique Krauze "el estado Mexicano: las fuentes de su legitimidad"; Gastón Baquero "Un Poema y un soneto"; Steven Weinberg "La ciencia y sus problemas en el fin de siglo";…Lezek Kolakowski "La miseria de nuestra Bella Época"; Marc Fumaroli "¿Cómo verían nuestro fin de siglo los moralistas del XVIII?"; Fernando Savater "Perplejidades éticas del siglo XX"; Hugo Vidal "Odas para un Yantar"; Adolfo Castañon "El humor y la desgana"; Teodoro González de León "Arquitectura y política"; Fabienne Bradu; Miguel Gomes; Nilo Palenzuela; . EXCELENTE ejemplar. 67pp + publicidad.
Thomas Eakins
Sewell, Darrel, 1939- Eakins, Thomas, 1844-1916Foster, Kathleen A.Philadelpia Museum of ArtMusée d'OrsayMetropolitan Museum of Art (New York, N.Y.); William Innes Homer, Carol Troyen, Mark Tucker and Nica Gutman, Marc Simpson, Kathleen A. Foster, W. Douglass Paschall, Mark Tucker and Nica Gutman, Elizabeth Milroy, H. Barbara Weinberg, Amy B. Werbel , Kathleen Brown,
Lingua: Inglese
Editore: Philadelphia Museum of Art in association with Yale University Press, Philadelphia, Pa, 2001, 2001
- Rilegato
- Prima edizione
Da: Joseph Valles - Books, Stockbridge, GA, U.S.A.Joseph Valles - Books
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Ottimo
EUR 54,99
EUR 14,60 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: Fine. Condizione sovraccoperta: Good. 1st Edition. xli, 446 p. : ill. (some col.) ; 32 cm. ISBN 9780876331439, 9780876331422, 9780300091113, 0876331436, 0876331428, 0300091117 ; OCLC 47785680 ; green cloth in color pictorial duistjacket ; creases on back dustjacket ; Contents: Thomas Eakins and American ar…t / Darrel Sewell -- Chronology / Kathleen Brown -- Eakins's early years / Amy B. Werbel -- Studies in Paris and Spain / H. Barbara Weinberg -- The 1870s / Marc Simpson -- Images of Fairmount Park in Philadelphia / Elizabeth Milroy -- Eakins and the academy / Kathleen A. Foster -- The 1880s / Marc Simpson -- Eakins's vision of the past and the building of a reputation / Marc Simpson -- Photographs and the making of paintings / Mark Tucker and Nica Gutman -- The camera artist / W. Douglass Paschall -- The 1890s / Marc Simpson -- Portraits of teachers and thinkers / Kathleen A. Foster -- The 1900s / Marc Simpson -- The pursuit of "true tones" / Mark Tucker and Nica Gutman -- Eakins in the twentieth century / Carol Troyen -- Eakins as a writer / William Innes Homer . Book.
Editore: New Haven [CT] & London: Yale University Press, 1997., 1997
- Rilegato
Da: Cornell Books Limited, Tewkesbury, Regno UnitoCornell Books Limited
Contatta il venditoreVenditore con 5 stelleMembro dell’associazione: PBFA
Condizione: Usato - Buono
EUR 23,98
EUR 20,37 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloCondizione: Good. Second impresssion (hardback). 4to (28cm by 23cm), 192pp. Illustrated throughout in b&w and colour. Original black cloth, dustwrapper. There is some foxing of the endpapers; overall, the book is in good to very good condition. The dustwrapper is in near-VG condition (minor chafing to one corner). ISBN 030007177…9.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Simpson, Marc; Sargent, John Singer; Ormond, Richard; Weinberg, H. Barbara; Sterling and Francine Clark Art Institute
- Brossura
Da: BennettBooksLtd, Los Angeles, CA, U.S.A.BennettBooksLtd
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 74,11
EUR 5,98 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
paperback. Condizione: New. In shrink wrap. Looks like an interesting title.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Simpson, Mr. Marc; Ormond, Richard [Contributor]; Weinberg, H. Barbara [Contributor];
- Rilegato
Da: BennettBooksLtd, Los Angeles, CA, U.S.A.BennettBooksLtd
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 76,16
EUR 5,98 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: New. In shrink wrap. Looks like an interesting title.
Uncanny Spectacle: The Public Career of the Young John Singer Sargent
Simpson, Marc; Sargent, John Singer; Ormond, Richard; Weinberg, H. Barbara; Sterling And Francine Clark Art Institute
- Brossura
Da: SHIMEDIA, Brooklyn, NY, U.S.A.SHIMEDIA
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 88,68
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Condizione: New. Satisfaction Guaranteed or your money back.
Janus 10. La enseñanza de masas ¿ es una buena inversión? El debate de la enseñanza
Andre Boulloche - Jean Capelle - Marc Zamansky - Alexander King - Roger Gregoire - Roger Brassart - Robert Escarpit - Alfred Sauvy - Gregorio Weinberg - Pierre Ichac - Jean Jacques Salomon - Jean Vedrine
Lingua: Spagnolo
Editore: Janus, 1968
- Brossura
Da: Librería Antonio Azorín, San Lorenzo de El Escorial, M, SpagnaLibrería Antonio Azorín
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Quasi ottimo
EUR 15,00
EUR 57,00 spedizioneSpedito da Spagna a U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloEncuadernación de tapa blanda. Condizione: Muy bien. Idioma español. Ejemplar en buen estado. 155 pp.
Gene Therapy for HIV and Chronic Infections
Berkhout, Ben (EDT); Ertl, Hildegund C. J. (EDT); Weinberg, Marco S. (EDT)
Lingua: Inglese
Editore: Springer, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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EUR 124,18
EUR 2,27 spedizioneSpedito in U.S.A.Quantità: Più di 20 disponibili
Condizione: New.
Lingua: Inglese
Editore: Springer, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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EUR 116,15
EUR 13,94 spedizioneSpedito da Regno Unito a U.S.A.Quantità: Più di 20 disponibili
Condizione: New. In.
Gene Therapy for HIV and Chronic Infections
Berkhout, Ben (EDT); Ertl, Hildegund C. J. (EDT); Weinberg, Marco S. (EDT)
Lingua: Inglese
Editore: Springer, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 116,14
EUR 17,46 spedizioneSpedito da Regno Unito a U.S.A.Quantità: Più di 20 disponibili
Condizione: New.
Lingua: Inglese
Editore: Springer, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: Books Puddle, New York, NY, U.S.A.Books Puddle
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 146,09
EUR 3,44 spedizioneSpedito in U.S.A.Quantità: 4 disponibili
Condizione: New. pp. 236.
Lingua: Inglese
Editore: Springer, 2016
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Brossura
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 116,53
EUR 30,50 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-…HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.
Lingua: Inglese
Editore: Springer, 2016
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Brossura
Da: Books Puddle, New York, NY, U.S.A.Books Puddle
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 159,36
EUR 3,44 spedizioneSpedito in U.S.A.Quantità: 4 disponibili
Condizione: New. pp. 236.
Gene Therapy for HIV and Chronic Infections
Berkhout, Ben (Edited by)/ Ertl, MD, Hildegund CJ (Edited by)/ Weinberg, Marc S. (Edited by)
Lingua: Inglese
Editore: Springer, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 153,66
EUR 14,55 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 2 disponibili
Hardcover. Condizione: Brand New. 1st edition. 236 pages. 9.50x6.00x0.75 inches. In Stock.
Lingua: Inglese
Editore: Springer, 2016
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Brossura
Da: preigu, Osnabrück, Germaniapreigu
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 95,25
EUR 70,00 spedizioneSpedito da Germania a U.S.A.Quantità: 5 disponibili
Taschenbuch. Condizione: Neu. Gene Therapy for HIV and Chronic Infections | Ben Berkhout (u. a.) | Taschenbuch | xvi | Englisch | 2016 | Springer | EAN 9781493948659 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Gene Therapy for HIV and Chronic Infections (Advances in Experimental Medicine and Biology)
Berkhout, Ben (Editor) / Ertl, Hildegund C.J. (Editor) / Weinberg, Marc S. (Editor)
Lingua: Inglese
Editore: Springer, 2016
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Brossura
Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 176,81
EUR 11,64 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Brand New. reprint edition. 252 pages. 9.25x6.10x0.60 inches. In Stock.
Lingua: Inglese
Editore: Springer New York, 2015
Serie: Libro 65 di 490 - Advances in Experimental Medicine and Biology
- Rilegato
Da: Buchpark, Trebbin, GermaniaBuchpark
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Ottimo
EUR 83,44
EUR 105,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Condizione: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti…-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990¿s. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.
