springer basel jul 2013 (19 risultati)

Taschenbuch. Condizione: Neu. Neuware -Gamma-Glutamyl Transpeptidases (¿-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the ¿-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released ¿-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). ¿-GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxidant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis.¿-GT is upregulated during inflammation and in several human tumors, and it is involved in many physiological disorders related to oxidative stress, such as Parkinson¿s disease and diabetes. Furthermore, this enzyme is used as a marker of liver disease and cancer. This book coverscurrent knowledge about the structure-function relationship of ¿-GTs andgives information aboutapplications of ¿-GTs in different fields ranging from clinical biochemistry to biotechnology and biomedicine.¿Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 68 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This tenth volume in the Poincaré Seminar Series describes recent developments at one of the most challenging frontiers in statistical physics - the deeply related fields of glassy dynamics, especially near the glass transition, and of the statics and dynamics of granular systems. These fields are marked by a vigorous interchange between experiment, theory, and numerical studies, all of which are well represented by the leading experts who have contributed articles to this volume. These articles are also highly pedagogical, as befits their origin in lectures to a broad scientific audience. Highlights include a Galilean dialogue on the mean field and competing theories of the glass transition, a wide-ranging survey of colloidal glasses, and experimental as well as theoretical treatments of the relatively new field of dense granular flows. This book should be of broad general interest to both physicists and mathematicians.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 172 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as ¿junk DNA¿, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5¿ and 3¿ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.¿Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 64 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Vor mehr als 300 geladenen Gästen feierte das Bundesamt für Verbraucherschutz und Lebensmittelsicherheit (BVL) am 31. Oktober 2012 in Braunschweig sein zehnjähriges Bestehen mit einem fachlichen Symposium und einer Festveranstaltung. Die Vorträge der Referenten des Fachsymposiums und die Grußworte der Festredner sind in diesem Bericht abgedruckt. Impressionen der Jubiläumsveranstaltung und eine Aufbereitung der zehnjährigen BVL-Geschichte ergänzen den Bericht. Dieser bietet somit einen Blick auf die Vergangenheit des gesundheitlichen Verbraucherschutzes in Deutschland als auch auf die Perspektiven des BVL in der Zukunft.¿Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 96 pp. Deutsch.

Taschenbuch. Condizione: Neu. Neuware -InhaltsangabePreface.- 1.What is a logical diagram (Catherine Legg).- 2.The geometry of diagrams and the logic of syllogisms (Richard Bosley).-3.A diagrammatic calculus of syllogisms (Ruggero Pagnan).- 4.Beyond syllogisms: Carroll's (marked) quadriliteral diagram (Amirouche Moktefi).- 5.A diagrammatic bridge between classical and fuzzy logics(Ferdinando Cavaliere).- 6.Diagrammatic reasoning with Classes and relationships (Jørgen Fischer Nilsson).-7.On the completeness of spider diagrams augmented with constants (Gem Stapleton, John Howse, Simon Thompson, John Taylor and Peter Chapman).- 8.A practice-based approach to diagrams (Valeria Giardino).- 9.Figures, formulae, and functors (Zach Weber).- 10.Diagrams and concepts of graph theory (Mitsuko Mizuno).Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 216 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -These proceedings represent the current state of research on the topics 'boundary theory' and 'spectral and probability theory' of random walks on infinite graphs. They are the result of the two workshops held in Styria (Graz and St. Kathrein am Offenegg, Austria) between June 29th and July 5th, 2009. Many of the participants joined both meetings. Even though the perspectives range from very different fields of mathematics, they all contribute with important results to the same wonderful topic from structure theory, which, by extending a quotation of Laurent Saloff-Coste, could be described by 'exploration of groups by random processes'.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 352 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The book provides a quick overview of a wide range of active research areas in partial differential equations. The book can serve as a useful source of information to mathematicians, scientists and engineers. The volume contains contributions from authors from a large variety of countries on different aspects of partial differential equations, such as evolution equations and estimates for their solutions, control theory, inverse problems, nonlinear equations, elliptic theory on singular domains, numerical approaches.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 376 pp. Englisch.

Buch. Condizione: Neu. Neuware -Quaternion andClifford Fourier and wavelet transformations generalize the classical theory to higher dimensions and are becoming increasingly important in diverse areas of mathematics, physics, computer science and engineering. This edited volume presents the state of the art in these hypercomplex transformations. The Clifford algebras unify Hamilton¿s quaternions with Grassmann algebra. A Clifford algebra is a complete algebra of a vector space and all its subspaces including the measurement of volumes and dihedral angles between any pair of subspaces. Quaternion and Clifford algebras permit the systematic generalization of many known concepts.This book provides comprehensive insights into current developments and applications including their performance and evaluation. Mathematically, it indicates where further investigation is required. For instance, attention is drawn to the matrix isomorphisms for hypercomplex algebras, which will help readers to see that software implementations are within our grasp.It also contributes to a growing unification of ideas and notation across the expanding field of hypercomplex transforms and wavelets. The first chapter provides a historical background and an overview of the relevant literature, and shows how the contributions that follow relate to each other and to prior work. The book will be a valuable resource for graduate students as well as for scientists and engineers.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 368 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Swaps, futures, options, structured instruments - a wide range of derivative products is traded in today's financial markets. Analyzing, pricing and managing such products often requires fairly sophisticated quantitative tools and methods. This book serves as an introduction to financial mathematics with special emphasis on aspects relevant in practice. In addition to numerous illustrative examples, algorithmic implementations are demonstrated using 'Mathematica' and the software package 'UnRisk' (available for both students and teachers). The content is organized in 15 chapters that can be treated as independent modules. In particular, the exposition is tailored for classroom use in a Bachelor or Master program course, as well as for practitioners who wish to further strengthen their quantitative background. 191 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 38 of 'Progress in Drug Research' contains four reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with novel quinolones and their antibacterial properties; neu ropeptides and their immunoregulatory role; the new generation of monoamine oxidase inhibitors and their potential use in Parkin son's disease; and with alternative approaches to the discovery of novel antipsychotic agents. These four reviews present important tools in the search for new and useful medicines. In the 32 years that 'Progress in Drug Research' has existed, the Editor has enjoyed the valuable help and advice of many col leagues. Readers, the authors of the reviews, and, last but not least, the reviewers have all contributed greatly to the success of the series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a review series. 377 pp. Englisch.