Springer berlin heidelberg dez 2012 (502 risultati)

Taschenbuch. Condizione: Neu. Neuware -Die regenerativen Energietrager haben bereits heute einen signifikanten Anteil an der weltweiten Stromerzeugung. 1m Jahre 1997 trugen sie knapp 20 % zur Gesamt produktion von etwa 12. 000 TWh bei. Dieser Anteil wurde fast ausschlieBlich von der Wasserkraft gedeckt, der Beitrag der Solarthermie war mit 0,7 TWh sehr klein, obwohl bereits Ende des letzten, Anfang dieses Jahrhunderts erste Anlagen u. a. zum Antrieb von Bewasserungspumpen auf Basis solarthermischer Stromerzeugung gebaut wurden. Der Einsatz von kostengtinstigerem 01 und anderen fossilen Brenn stoffen verhinderte damals weitere Entwicklungen, und erst mit dem Beginn der Energiekrise 1973/74 wurden diese Technologien neu entdeckt. Wahrend die Para bolrinnenkraftwerke SEGS I-IX mit 354 MWel in Kalifornien schon bewiesen, daB unter gtinstigen Rahmenbedingungen ein kommerzieHer Betrieb moglich ist, bieten z. B. Paraboloidkraftwerke mit im Brennpunkt angeordneten Stirling-Motoren erst die Perspektive, bei Serienfertigung Strom in abgelegenen Gebieten des aquatoria len Gtirtels giinstiger zu gestehen als die dort bisher genutzten Dieselaggregate. ABe solarthermischen Anlagen erfordern eine direkte Einstrahlung von mindestens 2 1800 kWh/m a, so daB ihr Einsatz nur in Gebieten zwischen etwa 40° nordlicher und siidlicher Breite, also beispielsweise nicht in Deutschland, okonomisch sinnvoH ist. Das hier vorliegende Buch ist aus dem Skriptum zur Vorlesung 'Stromerzeugung durch erneuerbare Energietrager', weche an der Ruhr-Universitat Bochum seit dem Wintersemester 1996 als Wahlfach bzw. als Teilnahmefach der Vertiefungsrichtung 'Energieversorgung' gelesen wird, hervorgegangen. 192 pp. Deutsch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study of the genetic basis for evolution has flourished in this century, as well as our understanding of the evolvability and programmability of biological systems. Genetic algorithms meanwhile grew out of the realization that a computer program could use the biologically-inspired processes of mutation, recombination, and selection to solve hard optimization problems. Genetic and evolutionary programming provide further approaches to a wide variety of computational problems. A synthesis of these experiences reveals fundamental insights into both the computational nature of biological evolution and processes of importance to computer science. Topics include biological models of nucleic acid information processing and genome evolution; molecules, cells, and metabolic circuits that compute logical relationships; the origin and evolution of the genetic code; and the interface with genetic algorithms and genetic and evolutionary programming. 352 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of these lecture notes is to develop a theory of asymptotic expansions for functions involving two variables, while at the same time using functions involving one variable and functions of the quotient of these two variables. Such composite asymptotic expansions (CAsEs) are particularly well-suited to describing solutions of singularly perturbed ordinary differential equations near turning points. CAsEs imply inner and outer expansions near turning points. Thus our approach is closely related to the method of matched asymptotic expansions. CAsEs offer two unique advantages, however. First, they provide uniform expansions near a turning point and away from it. Second, a Gevrey version of CAsEs is available and detailed in the lecture notes. Three problems are presented in which CAsEs are useful. The first application concerns canard solutions near a multiple turning point. The second application concerns so-called non-smooth or angular canard solutions. Finally an Ackerberg-O'Malley resonance problem is solved. 176 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This research monograph provides a pedagogical and self-contained introduction to non-equilibrium quantum particle dynamics for inhomogeneous systems, up to and including a survey of recent breakthroughs pioneered by the authors and other groups. The theoretical approach is based on real-time Green's functions (Keldysh Green's functions), directly solving the two-time Kadanoff-Baym equations (KBE). This field has seen a rapid development over the last decade, with new applications emerging in plasma physics, semiconductor optics and transport, nuclear matter and high-energy physics. This text will be a valuable starting point and reference work for graduate students and researchers interested in the quantum dynamics of inhomogeneous systems. 144 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Kunita, H.:Stochastic differential equations and stochastic flows of diffeomorphisms.-Elworthy, D.: Geometric aspects of diffusions on manifolds.-Ancona, A.:Théorie du potential sur les graphs et les variétiés.-Emery, M.:Continuous martingales in differentiable manifolds. 516 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph derives direct and concrete relations between colored Jones polynomials and the topology of incompressible spanning surfaces in knot and link complements. Under mild diagrammatic hypotheses, we prove that the growth of the degree of the colored Jones polynomials is a boundary slope of an essential surface in the knot complement. We show that certain coefficients of the polynomial measure how far this surface is from being a fiber for the knot; in particular, the surface is a fiber if and only if a particular coefficient vanishes. We also relate hyperbolic volume to colored Jones polynomials.Our method is to generalize the checkerboard decompositions of alternating knots. Under mild diagrammatic hypotheses, we show that these surfaces are essential, and obtain an ideal polyhedral decomposition of their complement. We use normal surface theory to relate the pieces of the JSJ decomposition of the complement to the combinatorics of certain surface spines (state graphs). Since state graphs have previously appeared in the study of Jones polynomials, our method bridges the gap between quantum and geometric knot invariants. 184 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For centuries, natural law was the main philosophical legal paradigm. Now, it is a wonder when a court of law invokes it. Arthur Kaufmann already underlined a modern general 'horror iuris naturalis'. We also know, with Winfried Hassemer, that the succession of legal paradigms is a matter of fashion. But why did natural law become outdated Are there any remnants of it still alive today This book analyses a number of prejudices and myths that have created a general misconception of natural law. As Jean-Marc Trigeaud put it: there is a natural law that positivists invented. Not the real one(s). It seeks to understand not only the usual adversaries of natural law (like legalists, positivists and historicists) but also its further enemies, the inner enemies of natural law, such as internal aporias, political and ideological manipulations, etc. The book puts forward a reasoned and balanced examination of this treasure of western political and juridical though. And, if we look at it another way, natural law is by no means a loser in our times: because it lives in modern human rights. 88 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On the occasion of the 80th birthday of Rodolfo Stavenhagen, a distinguished Mexican sociologist and professor emeritus of El Colegio de Mexico, Úrsula Oswald Spring (UNAM/CRIM, Mexico) introduces him as a Pioneer on Indigenous Rights due to his research on human rights issues, especially when he served as United Nations Special Rapporteur on the rights of indigenous peoples. First, in a retrospective Stavenhagen reviews his scientific and political work for the rights of indigenous peoples. Seven of his classic texts address Seven Fallacies about Latin America (1965); Decolonializing Applied Social Sciences (1971); Ethnodevelopment: A Neglected Dimension in Development Thinking (1986); Human Rights and Wrongs: A Place for Anthropologists (1998); Indigenous Peoples and the State in Latin America: An Ongoing Debate (2000); Building Intercultural Citizenship through Education: A Human Rights Approach (2006); and Making the Declaration Work (2006). This volume discusses the emergence of indigenous peoples as new social and political actors at the national level in numerous countries, as well as on the international scene. This book introduces a trilogy of Briefs on Rodolfo Stavenhagen published in the same series Pioneers in Science and Practice. 184 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Inter-organizational Cooperation with SAP Solutions- now in its second edition -describes the potential for cooperation in supply chain networks as well as the use of mySAP solutions in an inter-organizational context. The main focus is on applications from the fields of XML/EDI, data warehousing, supply chain management and electronic markets. On the basis of five case studies from the automotive industry, the use of mySAP solutions is demonstrated in practice. This second edition has been totally revised to take account of current challenges concerning building up cooperation from both the management and the software perspective. In order to achieve this, the author team was expanded. 260 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The highly developed industrial countries today have to face the challenge of accelerated structural change. The problems arising from this process are tackled in very different ways. In the public discussion the different approaches of Japan on the one side and of Western European countries on the other have received consider able attention. Structural change in its economic, social and political aspects has been the subject of the 8th German-Japanese Seminar on Economics and Social Sciences, held at Cologne from the 24th to the 27th of September, 1984. The tradition of German-Japanese Seminars on Economics and Social Sciences goes back to 1966, when the first meeting was held at Tokyo. Among the first participants were Dr. Hiromi Arizawa, Dr. Kazuo Okochi, both professors at the University of Tokyo, and Dr. Karl Hax, professor at Frankfurt University. The objective of all seminars, which have been held since, has been the analysis of eco nomic and social problems of immediate interest in both countries. The records of former seminars, which have been published partly in Japanese, partly in German throw light upon the shift of empha sis toward new problems which took place during aperiod of 18 years. 204 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book develops a new theory of the modern economy. Conventional economic theory is (still) based on an essentially static notion of equilibrium. In contrast, this book offers an analysis of the economic process based on a truly dynamic approach. It understands modern economic activity as manifesting itself in a growth spiral. There are two main drivers of the dynamics of this spiral: steady money creation in the banking system, on the one hand; and the continuous inflow of energy and raw materials through the exploitation of natural resources, on the other. Both driving forces are generally neglected by the conventional theory. Understanding their role is absolutely essential for preventing our economy from being more and more exposed to financial and ecological crises. This book offers important insights about the functioning of the modern economy and addresses the specialist as well as the interested lay reader. 180 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -China is dramatically catching up and is rapidly becoming a leading technological innovator on the global scale. The number of Chinese firms with global ambitions is growing fast, more and more technological innovation is coming from China, and the number of patents in China is also growing steadily. The negative side of this development is the still insufficient protection of intellectual property in China. The phenomenon of counterfeits originating from China has increased constantly over the past two decades. Moreover, within the past ten years the scale of intellectual property theft has risen exponentially in terms of its sophistication, volume, the range of goods, and the countries affected. This book addresses managers dealing with innovation in China, and offers concrete advice on how Western firms can benefit from these innovations. Among others, it provides examples and checklists to help decision-makers active in China. 140 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Atlas of PET/CT Imaging in Oncology serves an educational purpose and is designed to teach radiologists and nuclear medicine specialists about important aspects of molecular imaging and nuclear medicine specialists about the benefits of anatomic imaging. It consists of a brief didactic portion and an extensive selection of interesting and challenging case examples. A special feature of the atlas is an interactive CD-ROM that provides the original PET and CT images of each case in selected planes enabling the users to manually adjust the blending intensity of each modality in a fused image. In addition, users can display the clinical history, imaging techniques and diagnostic findings of each case as well as the corresponding specific teaching point. 315 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In structure mechanics analysis, finite element methods are now well estab lished and well documented techniques; their advantage lies in a higher flexibility, in particular for: (i) The representation of arbitrary complicated boundaries; (ii) Systematic rules for the developments of stable numerical schemes ap proximating mathematically wellposed problems, with various types of boundary conditions. On the other hand, compared to finite difference methods, this flexibility is paid by: an increased programming complexity; additional storage require ment. The application of finite element methods to fluid mechanics has been lagging behind and is relatively recent for several types of reasons: (i) Historical reasons: the early methods were invented by engineers for the analysis of torsion, flexion deformation of bearns, plates, shells, etc . (see the historics in Strang and Fix (1972) or Zienckiewicz (1977'. (ii) Technical reasons: fluid flow problems present specific difficulties: strong gradients,l of the velocity or temperature for instance, may occur which a finite mesh is unable to properly represent; a remedy lies in the various upwind finite element schemes which recently turned up, and which are reviewed in chapter 2 (yet their effect is just as controversial as in finite differences). Next, waves can propagate (e.g. in ocean dynamics with shallowwaters equations) which will be falsely distorted by a finite non regular mesh, as Kreiss (1979) pointed out. We are concerned in this course with the approximation of incompressible, viscous, Newtonian fluids, i.e. governed by N avier Stokes equations. 172 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the rap1d development of computational capab1lities, nonl1near f1nite element analys1s 1n structural mechan1CS has become an 1mportant field of research. Its objective is the real1stic assessment of the actual behaV10r of structures by numerical methods. Th1S requires that all nonlinear effects, such as the nonl1near character1stics of the mater1al and large deformations be taken 1nto account. The act1vities in th1S f1eld be1ng worldw1de, d1rect 1nteraction between the various research groups 1S necessary to coordinate future research and to overcome the time gap between the generat10n of new results and the1r appearance 1n the 11terature. The f1rst U.S.-Germany Sympos1um was held 1n 1976 at the Massachusetts Inst1tute of Technology. Under the general to P1C 'Formulat1ons and Computat1onal Algorithms in Fin1te Ele ment Analysis' 1t prov1ded an opportun1ty for about 20 re searchers from each country to present lectures, hold discus sions, and establ1sh mutual contacts. The success of th1S first sympos1um was so encourag1ng that 1t seemed natural to organ- 1ze a second bilateral meet1ng, this time 1n Germany, and to 1nv1te researchers from other European countr1es as well. 792 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The first complete genome sequence of a multicellular organism, Caenorhabditis elegans, has been determined recently. Several more will follow soon, among them the genome sequences of Drosophila melanogaster and the human. With these achievements, the stage is set for the next phase of 'large-scale' biology, the study of the function of genes and the interactions between their protein products. The aim of the Ernst Schering Research Foundation Workshop 29 was to discuss the contribution of research on model organisms which are particularly suited for genetic and biological research, to the understanding of gen eral principles of biology as well as the basis for human diseases. This area of research has not only unveiled the basic molecular mechanisms of development of higher organisms, but has also made major contri butions to the elucidation of complex signal transduction pathways that play crucial roles both in ontogeny and human diseases. Establishing the complete molecular anatomy of an organism is a demanding but rather well-defined task. However, compared to the technical and scientific challenges of large-scale sequencing and the bioinformatics analysis of complete genome data, the assignment of function to the genes of multicellular organisms may still seem like a fishing expedition, with no universal road to success. One approach is based on large-scale technologies. The use of mi croarrays for multiple gene expression analysis is one element in this effort, providing important information on the cell- or tissue-specific activation of genes over time. 260 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book introduces laser drilling processes including modelling, quality assessment of drilled holes, and laser drilling applications. It provides insights into the laser drilling process and the relation among the drilling parameters pertinent to improved end product quality. This book is written for engineers and scientists working on laser machining, particularly laser drilling. 96 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book constitutes the refereed proceedings of the 8th International Joint Conference on E-Business and Telecommunications, ICETE 2011, held in Seville, Spain in July 2011.The 118 revised full papers presented were carefully reviewed and selected from 409 submissions. The topics covered are data communication networking, e-business, optical communication systems, security and cryptography, signal processing and multimedia applications, and wireless networks and information systems. These are the main knowledge areas that define the six component conferences, namely: DCNET, ICE-B, OPTICS, SECRYPT, SIGMAP, and WINSYS which together form the ICETE joint conference. 552 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A rich source of information about human voluntary movement in health and disease can be found in this book. The most esteemed researchers in their respective fields bring you up-to-date articles. Their collected work combines fundamental research in the life sciences with clinical neuroscience in a unique overview. The interdisciplinary aspects of motor physiology uncover a wealth of information for researchers from neighboring disciplines. For example, oculomotor research, vestibular research, equilibrium, sensory research and cognition, evolution, synaptic and elementary processes and the neurological sciences can be discovered. 700 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the notes from five lecture courses devoted to nonautonomous differential systems, in which appropriate topological and dynamical techniques were described and applied to a variety of problems. The courses took place during the C.I.M.E. Session 'Stability and Bifurcation Problems for Non-Autonomous Differential Equations,' held in Cetraro, Italy, June 19-25 2011. Anna Capietto and Jean Mawhin lectured on nonlinear boundary value problems; they applied the Maslov index and degree-theoretic methods in this context. Rafael Ortega discussed the theory of twist maps with nonperiodic phase and presented applications. Peter Kloeden and Sylvia Novo showed how dynamical methods can be used to study the stability/bifurcation properties of bounded solutions and of attracting sets for nonautonomous differential and functional-differential equations. The volume will be of interest to all researchers working in these and related fields. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the past decade, rapid progress had been made in elucidating the cellular and molecular mechanisms of new blood vessel formation in both health and disease. Lack of sufficient angiogenesis (new capillary development) and collateral formation (remodeling of existing blood vessels) in adult tissues (e. g. , heart, brain, skeletal muscle) during criti cal ischemia has prompted novel therapeutic strategies to stimulate/fa cilitate angiogenesis and collateral formation in ischemic conditions ('therapeutic angiogenesis'). Therapeutic angiogenesis describes a strategy of inducing new col lateral vessels that can bypass vascular obstructions caused by atherosclerotic disease and stimulating new capillaries that can en hance tissue oxygen exchange. Naturally occurring growth factors (e. g. , FGFs, VEGFs) have been identified and demonstrated to induce new blood vessel formation in the adult organism. The therapeutic ap plication of these growth factors has been demonstrated to enhance these natural processes and have been shown in a number of animal models to increase blood flow and oxygen exchange to ischemic tis sues. Therapeutic angiogenesis therefore represents a new medical principle that is anticipated to be used as an adjunct or alternative to angioplasty and/or bypass surgery. A number of strategies have been proposed and tested to deliver growth factors. One strategy is the direct administration of the growth factor protein by intramuscular, intraarte rial or intravenous delivery. 204 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Theoretical and numerical details of an optimized LCAO (linear combination of atomic orbitals) method for the calculation of self-consistent bandstructures are given together with a variety of examples. The method will be a valuable tool both for researchers engaged in calculations and for scientists looking for numerical results of self-consistent bandstructure calculations. The presentation starts with an introduction to the modern many-body theory of electronic bandstructure. The essentials of the representation with a non-orthogonal basis and the usual tight-binding variants are critically reviewed. A variational approach to the optimization of atom-like basis orbitals is described together with an SCF procedure for band calculations. Complete numerical and graphic results for all elementary metals from lithium to zinc are given. 224 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration. 224 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Agent technology has recently become one of the most vibrant and fastest growing areas in information technology. This is the first systematic introduction to software agents with the goal of exploiting them in future communication systems. The coherently written chapters provide complementary coverage of the relevant issues. Multi-agent systems and mobile agent approaches are presented and applied to important topics in future communication systems. 404 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -For a long time computer scientists have distinguished between fast and slow algo rithms. Fast (or good) algorithms are the algorithms that run in polynomial time, which means that the number of steps required for the algorithm to solve a problem is bounded by some polynomial in the length of the input. All other algorithms are slow (or bad). The running time of slow algorithms is usually exponential. This book is about bad algorithms. There are several reasons why we are interested in exponential time algorithms. Most of us believe that there are many natural problems which cannot be solved by polynomial time algorithms. The most famous and oldest family of hard problems is the family of NP complete problems. Most likely there are no polynomial time al gorithms solving these hard problems and in the worst case scenario the exponential running time is unavoidable. Every combinatorial problem is solvable in nite time by enumerating all possi ble solutions, i. e. by brute force search. But is brute force search always unavoid able De nitely not. Already in the nineteen sixties and seventies it was known that some NP complete problems can be solved signi cantly faster than by brute force search. Three classic examples are the following algorithms for the TRAVELLING SALESMAN problem, MAXIMUM INDEPENDENT SET, and COLORING. 220 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fractionation of polymers via solubility has been a well known method in polymer characterization for a long time. The original object of analytical fractionations, the determination of the molecular weight distribution, is nowadays achieved more efficiently and conveniently by chromatographic methods. However, fractionation procedures, which were developed in great diversity, remain up~to-date and essential for obtaining preparative fractions with narrow distributions. Such fractions are wanted increasingly for the investigation of true structure-property relationships which are mostly influ~ enced by distributions of molecular weight or other parameters such as branching or chemical composition. Literature on the field of polymer fractionation is extensive and several reviews exist. However, there is a lack of systematically methodical instruc tions for carrying-out of diverse fractionation procedures. This volume repre sents an attempt to reduce this deficiency and is focussed on practical aspects of fractionation procedures. This laboratory manual is intended for polymer chemists, physicists, and technicians, for students of polymer science, and skilled laboratory assistants, all of whom are not dealing directly with fractionation but are in need of fractions to carry out further investigations. 240 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer. It is based on the fact that our immune system can identify tumor cells and, once activated, is capable of developing specific immunity against the neoplastic cells. Numerous observations and intense research clearly document the major contribution of the immune system to the prevention of cancer. And there are many re ports of patients suffering from malignant melanoma or other tumors who mount a spontaneous immune response against their tumor cells that results in tumor regression. Based on the recent advances in our understanding of the compo nents of our immune system, their interactions and the regulation of immune responses, we are now able to design vaccination strategies that induce or enhance cell-mediated immunity against tumors. A ma jor advancement came with the identification and characterization of relevant tumor antigens, which are suitable target structures for anti-tu mor immune response. First clinical trials using such vaccine strategies have yielded encouraging results in patients. However, in spite of many reported cases of successful therapy of cancer by vaccination many patients still do not experience relief after such treatments. These initial clinical trials and the accompanying investigations have revealed a number of important results that indicate the direction of future re search and development in the field. 212 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While serendipity and random screening continue to fulfil a significant role in the search for new drugs, current remarkable advances in molecular biology and genetics are dictating to a profound extent the approaches employed in their development. Increasing attention is being devoted to investigations of the mechanisms of action of existing drugs, and the sources of undesired side effects, at the molecular level. The information so derived is now extensively applied, with the aid of broad inter disciplinary approaches, both theoretical and experimental, to improvements in existing drugs, and the rational design of new ones. The foregoing comprised the subject matter of the 3rd Inter national Symposium on 'Molecular Aspects of Chemotherapy', under the auspices of the International Society of Chemotherapy, and organized by the Committee on Drug Research, Polish Academy of Sciences, and the Department of Biotechnology and Biochemistry, Technical University of Gdansk. This volume includes the texts of the review lectures presented by invited participants on up-to-date achievements, and future perspectives, in molecular mechanisms of inhibition of cellular functions and metabolism, with emphasis on the design and mechanisms of action of chemotherapeutic agents for treatment of bacterial, neoplastic, viral and parasitic diseases. From the Contents, it will be seen that the range of disciplines represented was a broad one, including theoretical and experimental chemists, physicists, molecular biologists, biochemists, enzymologists, virologists, tumour biologists. Plenary sessions were supple mented by several poster sessions. 288 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Augmented Spherical Wave (ASW) method is one of the most powerful approaches to handle the requirements of finite basis sets in DFT calculations. It is particularly suited for the calculation of the electronic, magnetic, and optical properties of solid-state materials. Recent developments allow application, in addition, to the elastic properties and phonon spectra. Due to the localized nature of the ASW basis set these properties can be easily interpreted in terms of atomic-like orbitals. The book addresses all those who want to learn about methods for electronic structure calculations and the ASW method in particular. This new edition has been thoroughly revised and extended. In particular, a chapter on the new, both very efficient and accurate spherical-wave based full potential ASW method has been added. 396 pp. Englisch.…

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This introduction to cryptography employs a programming-oriented approach to study the most important cryptographic schemes in current use and the main cryptanalytic attacks against them. Discussion of the theoretical aspects, emphasizing precise security definitions based on methodological tools such as complexity and randomness, and of the mathematical aspects, with emphasis on number-theoretic algorithms and their applications to cryptography and cryptanalysis, is integrated with the programming approach, thus providing implementations of the algorithms and schemes as well as examples of realistic size. A distinctive feature of the author's approach is the use of Maple as a programming environment in which not just the cryptographic primitives but also the most important cryptographic schemes are implemented following the recommendations of standards bodies such as NIST, with many of the known cryptanalytic attacks implemented as well. The purpose of the Maple implementations is to let the reader experiment and learn, and for this reason the author includes numerous examples. The book discusses important recent subjects such as homomorphic encryption, identity-based cryptography and elliptic curve cryptography. The algorithms and schemes which are treated in detail and implemented in Maple include AES and modes of operation, CMAC, GCM/GMAC, SHA-256, HMAC, RSA, Rabin, Elgamal, Paillier, Cocks IBE, DSA and ECDSA. In addition, some recently introduced schemes enjoying strong security properties, such as RSA-OAEP, Rabin-SAEP, Cramer--Shoup, and PSS, are also discussed and implemented. On the cryptanalysis side, Maple implementations and examples are used to discuss many important algorithms, including birthday and man-in-the-middle attacks, integer factorization algorithms such as Pollard's rho and the quadratic sieve, and discrete log algorithms such as baby-step giant-step, Pollard's rho, Pohlig--Hellman and the index calculus method.This textbook is suitable for advanced undergraduate and graduate students of computer science, engineering and mathematics, satisfying the requirements of various types of courses: a basic introductory course; a theoretically oriented course whose focus is on the precise definition of security concepts and on cryptographic schemes with reductionist security proofs; a practice-oriented course requiring little mathematical background and with an emphasis on applications; or a mathematically advanced course addressed to students with a stronger mathematical background. The main prerequisite is a basic knowledge of linear algebra and elementary calculus, and while some knowledge of probability and abstract algebra would be helpful, it is not essential because the book includes the necessary background from these subjects and, furthermore, explores the number-theoretic material in detail. The book is also a comprehensive reference and is suitable for self-study by practitioners and programmers. 736 pp. Englisch.…