Springer springer us sep 2011 (770 risultati)
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Taschenbuch. Condizione: Neu. Neuware - Volume 8 of Advances in Nutritional Research deals with several topics of prime current interest in nutritional research, including the role of nutrition in hypertension, in the infections associated with protein-energy malnu trition, and in pathological conditions associated with the gene…ration of oxygen radicals in the tissues, as well as with topics of ongoing interest. Recent research indicates that reduction of obesity, of alcohol intake, and of sodium intake by salt-sensitive individuals, are the most effective non pharmacological means of reducing high blood pressure. A new approach to therapy for infections caused by protein-energy malnutrition, based on restoration of immunocompetence by administration of thyroid and anti glucocorticoid hormones, is presented. Current research into the role of nutrition in modulating tissue damage caused by oxygen radicals generated in various pathologies is reviewed. Two chapters deal with perinatal nutrition, one with the transfer of nutrients across the placenta and the other with the energy requirements of term and preterm infants. Another dicusses methods of assessing the nutritional status of hospitalized patients. vii Contents Chapter 1. The Transfer of Nutrients across the Perfused Human Placenta . . Joseph Dands 1. Introduction. 1 2. Comments on Comparative Placentology . . . . . . . . . . .- . . 1 . 3. The Perfusion Technique . . . . . . . . . . . . . . . . . . . . 3 . . . . 4. Review of Transfer Experiments . 3 4.1. Transfer of Glutamic Acid . 3 4.2. Transfer of Riboflavin . . . . . . . . . . . . . . . -. . . 6 . . . 5. Potentials and Umltations . . . . . . . . . . . . . . . . . . . 9 . . . .References . . . . . . . . . . . . . . . . . . . . . . . . . . 10 . . . . . .
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Taschenbuch. Condizione: Neu. Neuware - Computing systems researchers confront two serious problems. (1) The increasingly monolithic, or pseudo-monolithic, integration of complex com puting functions and systems imposes an environment which integrates ad vanced principles and techniques from a broad variety of fields. Researcher…s not only must confront the increased complexity of topics in their specialty field but also must develop a deeper general understanding of a broadening number of fields. (2) There has been a proliferation of journals, books, workshops and conferences through which research results are reported. Remaining familiar with recent advances in our specific fields is a major challenge. Casually browsing through journals and conference proceedings to remain aware of developments in areas outside our specialization has become an even greater challenge. Frontiers of Computing Systems Research has been established to ad dress these two issues. With the assistance of an advisory board of experts from a wide variety of specialized areas, we hope to provide roughly annual volumes of invited chapters on a broad range of topics and designed for an interdisciplinary research audience. No single volume can cover all the rel evant topics and no single article can convey the full set of directions being pursued within a given topic. For this reason, a chapter listing technical reports available from universities is also included. Often, such unpub lished reports are designed for a general research audience and provide a good, informal look at trends in specialized research topics.
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Taschenbuch. Condizione: Neu. Neuware - A great truth is a truth whose opposite. is also a great truth. Thomas Mann (Essay on Freud, 1937) This volume centers on pseudorabies (PR V), herpes simplex viruses 1 and 2 (HSV-1 and HSV-2), and human cytomegalovirus (CMV) and fulfills three objectives. The chapters on the epidemiology a…nd latency of HSV, and on the glycoproteins specified by HSV and CMV, set the stage for the discussions of the immunobiology and pathogenesis of human herpesvirus infections in Volume 4. The epidemiology of HSV is the basis of our understanding of the spread and survival of this virus in the human populations. Central to the epidemiology of HSV and its pathogenesis in humans is the ability of the virus to remain in a latent state for the life of its host. The viral membrane glycoproteins are among the most interesting virion proteins, primarily because of their critical role in the initiation of infection. Since they are the surface membrane proteins of the virion and appear on the surface of productively infected cells, they are also the obvious if not the exclusive targets of the immune response. The chapters on the transforming potential of HSV and CMV, and on the role of HSV in human cancer, deal with challenging problems requiring rather different experimental tools.
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Taschenbuch. Condizione: Neu. Neuware - Advances in Solar Energy is back on schedule. Volume III contains a number of interesting reviews of the different fields in solar energy conversion. We appreciate the many encouraging comments received after the second volume appeared and have incorporated some of the suggested changes. E…ven though most of the reviews are invited through our editors, we are always open to suggestion about subjects of importance that are ready for a com prehensive and critical review and have not been recently covered, or about potential authors. I would like to take this opportunity to thank Professor John A. Duffie for his invaluable help in starting the Advances in Solar Energy series. Although he has recently taken full responsibility as editor-in-chief for the Solar Energy Journal, his continued assistance as a member of the Board of Editors is greatly appreciated. The diligent work of the many active editors is gratefully acknowledged and constitutes the basis for a valuable review periodical with outstanding contributions. The typesetting was done by Sandra Pruitt in the Delaware office, using the TEX-program with laser print-out. Her organization and patience in coordinating with the authors, and her technical skill and diligence in preparing the submitted copy permitted the timely and high-quality assembly of this production. We wish to commend her for efforts well beyond the call of duty. The accommodating help from Plenum Press and its production staff deserves our grateful acknowledgement.
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Taschenbuch. Condizione: Neu. Neuware - This book has been written as part of a new series of scientific text-books being published by Plenum Publishing Company Limited. The scope of the series is to review a chosen topic in each volume, and in addition, to present abstracts of the most important references cited in the text. Th…us allowing the reader to supplement the information contained within this book without have to refer to many additional publications. This volume is devoted to the subject of Radiation Detectors, known as Photodetectors, and particular emphasis has been placed on devices operating in the infrared region of the electromagnetic spectrum. Although some detectors which are sensitive at ultraviolet and visible wavelengths, are also described. The existence of the infrared region of the spectrum has been known for almost two hundred years but the development of detectors specifically for these wavelengths was limited for a long time due to technology limitations and difficulties in understanding and explaining the phenomena involved. Significant advances were made during World War II, when the potential military applications of being able 'to see in the dar~' were demonstrated, and this progress has been maintained during the last forty years when many major advances have been achieved, such that the use of photodetectors for both civil and military applications is now relatively common and can be inexpensive.
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Taschenbuch. Condizione: Neu. Neuware - Wireless personal communications, or wireless as it is now being called, has arrived. The hype is starting to fade, and the hard work of deploying new systems and services for personal communications is underway. In the United States, the FCC propelled the wireless era from infancy to main…stream with a $7.7 billion auction of 60 MHz of radio spectrum in the 180011900 MHz band. With the largest single sale of public property in the history of mankind mostly complete, the resources of the entire world are being called upon to develop inexpensive, rapidly deployable wireless systems and sub scriber units for an industry that is adding subscribers at greater than 50% annual rate. This growth is commonplace for wireless service companies throughout the world, and in the U.S., where as many as 7 licensed wireless service providers may be competing for cellularfPCS customers within the next couple of years, differentiators in cost, qual ity, service, and coverage will become critical to customer acceptance and use. Many of these issues are discussed in the papers included in this book.
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Taschenbuch. Condizione: Neu. Neuware - Very large scale integration (VLSI) technologies are now maturing with a current emphasis toward submicron structures and sophisticated applications combining digital as well as analog circuits on a single chip. Abundant examples are found on today's advanced systems for telecom munication…s, robotics, automotive electronics, image processing, intelli gent sensors, etc . Exciting new applications are being unveiled in the field of neural computing where the massive use of analog/digital VLSI technologies will have a significant impact. To match such a fast technological trend towards single chip ana logi digital VLSI systems, researchers worldwide have long realized the vital need of producing advanced computer aided tools for designing both digital and analog circuits and systems for silicon integration. Ar chitecture and circuit compilation, device sizing and the layout genera tion are but a few familiar tasks on the world of digital integrated circuit design which can be efficiently accomplished by matured computer aided tools. In contrast, the art of tools for designing and producing analog or even analogi digital integrated circuits is quite primitive and still lack ing the industrial penetration and acceptance already achieved by digital counterparts. In fact, analog design is commonly perceived to be one of the most knowledge-intensive design tasks and analog circuits are still designed, largely by hand, by expert intimately familiar with nuances of the target application and integrated circuit fabrication process. The techniques needed to build good analog circuits seem to exist solely as expertise invested in individual designers.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 141 di 180. Libro 141 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimin…ary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdividions such as lung cancer, genitouri nary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Developments in Cardiovascular Medicine, Libro 208 di 253. Libro 208 di 253 - Developments in Cardiovascular Medicine
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Taschenbuch. Condizione: Neu. Neuware - The first Taurine Symposium organized by Dr. Ryan Huxtable and the late Dr. Andre Barbeau was held in Tucson, Arizona, in 1975. Since that auspici ous event, nine international symposia on the role of taurine in biology have taken place. The locations for these meetings have been Tucson (t…wo times), Rome, Philadelphia, Tokyo, Vancouver, Mexico City, Helsinki, and Florence. In 1977, due to the large number of scientists in Japan who were interested in the role of this unique amino acid in biological systems, we organized the Japanese Research Society on Sulfur Amino Acids with the encouragement and financial assistance of the Taisho Pharmaceutical Co., Ltd (Tokyo). Annual meetings have been held, and the membership has expanded from 78 to 414 in 1987; the number of presentations has increased during this time span from 29 to 74. The symposium in Tokyo in 1982, 'Sulfur Amino Acids, Biochemical and Clinical Aspects' [1], was held to celebrate the 5th Annual Meeting of our Society. I would like to emphasize that in Japan we have an active Research Society especially directed to the study of sulfur amino acids. We have published our own semi-annual journal entitled Sulfur Amino Acids. Our society is an inter disciplinary research society since taurine is a highly diversified compound that interconnects physiology, biochemistry, pharmacology, nutrition, and medicine. One exciting fringe benefit of taurine research and the society has been the fostering of contacts with distinguished scientists from many varied medical fields.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 106 di 180. Libro 106 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - Cytological screening for the identification of intraepithelial neoplasia of the cervix as a precursor lesion for cervical cancer has been well established as an effective means for decreasing the incidence of invasive carcinoma. Despite these screening efforts, carcinoma of the cervix rem…ains one of the more common malignancies in women and it is the leading cause of cancer death in many countries in the western hemisphere. It is estimated that in 1986 there will still be 14,000 new cases of invasive cancer, with 6,800 deaths in the United States alone. Unfortunately, many of these patients present with advanced disease, posing difficult management problems for the clinician responsible for their care. The treatment of early stage invasive carcinoma of the cervix (lesions confined to the cervix and vagina) remains either radical surgery, radical radiation therapy or a combination thereof This approach is extraordinarily effective in the vast majority of patients. However, there remains a subset of patients with early stage disease that are at high risk for recurrence. Dr Kjorstad (Chapter 2) has identified adenocarcinomas and adenosqua mous carcinomas as having a particularly poor prognosis. In addition, patients with more than three positive lymph nodes or with involvement of lymph nodes outside of the pelvis have a very poor prognosis. He has iden tified the CEA as a potentially predictive marker for these patients with poor prognosis, especially in patients with adenocarcinomas.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: The Springer International Series in Engineering and Computer Science, Libro 170 di 260. Libro 170 di 260 - The Springer International Series in Engineering and Computer Science
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Taschenbuch. Condizione: Neu. Neuware - This book, and the research it describes, resulted from a simple observation we made sometime in 1986. Put simply, we noticed that many VLSI design tools looked 'alike'. That is, at least at the overall software architecture level, the algorithms and data structures required to solve probl…em X looked much like those required to solve problem X'. Unfortunately, this resemblance is often of little help in actually writing the software for problem X' given the software for problem X. In the VLSI CAD world, technology changes rapidly enough that design software must continually strive to keep up. And of course, VLSI design software, and engineering design software in general, is often exquisitely sensitive to some aspects of the domain (technology) in which it operates. Modest changes in functionality have an unfortunate tendency to require substantial (and time-consuming) internal software modifications. Now, observing that large engineering software systems are technology dependent is not particularly clever. However, we believe that our approach to xiv Preface dealing with this problem took an interesting new direction. We chose to investigate the extent to which automatic programming ideas cold be used to synthesize such software systems from high-level specifications. This book is one of the results of that effort.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 105 di 180. Libro 105 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diag nosis or management of a particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preli…minary reports on a very limited number of patients. Certain general journals fre quently publish good in-depth reviews of cancer topics, and published sym posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by di viding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Developments in Cardiovascular Medicine, Libro 64 di 253. Libro 64 di 253 - Developments in Cardiovascular Medicine
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Taschenbuch. Condizione: Neu. Neuware - This monograph contains 20 selected papers presented at the Symposium on Subcellular Basis of Contractile Failure which was held in Ottawa during May 11-13, 1989 and is designed for the benefit ofthose who were unable to attend this event. It is now increasingly becoming clear that an exce…ssive amount of calcium is intimately involved in the pathogenesis of a wide variety of heart diseases. Accordingly, the investigations concerning the role of calcium chan nels and their regulatory mechanisms in heart function as well as of the intra cellular calcium overload in cardiac dysfunction are presented here. Since sodium is also considered to influence the cardiac contractile force by chang 2 ing the intracellular concentration of calcium through the Na +-Ca+ exchange 2 mechanism in the cell membrane, the role of Na +-Ca+ exchange in heart func tion as well as pathology of contractile failure is discussed. In view of the new ly discovered implications of the oxygen free radicals in cellular injury, papers concerning the role of these radicals in heart disease are included in this book. For the purpose of clarity, different chapters have been organized under three main headings: (I) Role of cations in heart function, (II) Cardiac hypertrophy and cardiomyopathies, and (III) Ischemic heart disease and cardiac failure.
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Taschenbuch. Condizione: Neu. Neuware - After the great success of the fIrst issue of the series, the International Yearbook of Nephrology 1989, we were encouraged to proceed in our editorial venture to update nephrologists yearly, on all rapidly-changing areas of nephrology. Thus we have chosen new topics and appointed experts…in the fIeld, asking them to give an objective review of the topic, up-dating the readers on the world-wide literature and providing them with a complete, accurate and up-to-date list of important, recent references. We have decided to maintain the successful format of the International Yearbook of Nephrology 1989. Thus each annual issue will be devided into sections; each section will have a different primary focus every year, depending upon what area is of greatest interest at the time. In other words, the Yearbook will remain different from the numerous books which appear every year covering all aspects of nephrology. In the Yearbooks you will fInd topics usually anavailable in nephrology textbooks. In this issue we have improved the printing quality of the book, with a more uniform format throughout the volume, despite the use of camera-ready manuscripts for direct photo-offset reproduction (a procedure mandatory for a rapid publication).
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Developments in Cardiovascular Medicine, Libro 184 di 253. Libro 184 di 253 - Developments in Cardiovascular Medicine
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Taschenbuch. Condizione: Neu. Neuware - Our understanding of the pathophysiology of acute myocardial infarction has grown enormously in recent years. This has led to an increasingly aggressive approach to management, designed to blunt the extent of infarction by salvaging acutely ischemic myocardium. Alternatives now include thr…om bolysis, PTCA with and without prior thrombolysis, and emergency bypass surgery, as well as the more aggressive use of a variety of drugs. This book consists of a series of chapters by experienced cardiologists and cardiovascular surgeons that present today's state of the art in managing acute myocardial infarction. It is written with the purpose of presenting practical approaches of value to the clinician related to the more complex problems faced in dealing with patients undergoing myocardial infarction. xi EARLY INTERVENTIONS IN ACUTE MYOCARDIAL INFARCTION 1. MANAGEMENT OF ARRHYTHMIAS IN THE CORONARY CARE UNIT NORA GOLDSCHLAGER, RODERICK WOODS, AND NEAL BENOWITZ With the advent of coronary care units, mortality from cardiac arrhythmias occurring during acute myocardial infarction has been unquestionably and dramatically reduced. In addition, continuous electrocardiographic monitoring has resulted in the recognition of specific arrhythmias related to acute ischemic heart disease and thus to the development of appropriate strategies for their management. This chapter will review certain specific aspects of those bradyarrhythmias and atrial and ventricular tachyarrhythmias that are seen most commonly in acute myocardial infarction. Pharmacologic therapy, including the use of some of the newer antiarrhythmic agents, will be discussed, as will pacemaker ther apy of both bradyarrhythmias and tachyarrhythmias.
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Taschenbuch. Condizione: Neu. Neuware - For a period of some fifteen years following completion of my internship training in clinical psychology (1950-1951) at the Washington University School of Medicine and my concurrent successful navigation through that school's neuroanatomy course, clinical work in neuropsychology for me an…d the psychologists of my generation consisted almost exclusively of trying to help our physician colleagues differentiate patients with neurologic from those with psychiatric disorders. In time, experience led all of us from the several disciplines involved in this enterprise to the conclusion that the crude diag nostic techniques available to us circa 1945-1965 had garnered us little valid information upon which to base such complex, differential diagnostic decisions. It now is gratifying to look back and review the remarkable progress that has occurred in the field of clinical neuropsychology in the four decades since I was a graduate student. In the late 1940s such pioneers as Ward Halstead, Alexander Luria, George Yacorzynski, Hans-Lukas Teuber, and Arthur Benton already were involved in clinical studies that, by the late 1960s, would markedly have improved the quality of clinical practice. However, the only psychological tests that the clinical psychologist of my immediate post-Second World War generation had as aids for the diagnosis of neurologically based conditions involving cognitive deficit were such old standbys as the Wechsler Bellevue, Rorschach, Draw A Person, Bender Gestalt, and Graham Kendall Memory for Designs Test.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 136 di 180. Libro 136 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - The last volume dealing with lung cancer in this series in Cancer Treatment and Research was published in 1986 and entitled Lung Cancer: Basic and Clinical Aspects. The present book continues the outline of the previous volume by presenting up-to-date information on lung cancer in critical… reviews of new important basic and clinical concepts of lung cancer. The present volume has broadened the scope by also including chapters dealing with issues such as epidemiology, prophylaxis, and histopathology of lung cancer. The content of the book thus reflects the increasing awareness of a global disease that is more and more in focus, not only scientifically but also politically. The latter fact results increasingly in changes in health legisla tion, with prevention measures influencing everyday life. The great interest in the disease is natural, considering that more than one patient dies from lung cancer every minute globally. The first chapter is from the Cancer Unit, WHO, Geneva, and describes in detail the epidemiologic features of lung cancer, which is the second most frequent cancer in the world with 660,500 new cases annually; it will soon surpass stomach cancer as the leader. Thirty-one percent of the cases occur in developing countries, where the increase is especially dramatic.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 107 di 180. Libro 107 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology text books are generally out of the date. Single papers in specialized journals are informative but seldom comprehensive; these are often prelim…inary reports on a very limited number of patients. Certain general journals frequently publish good in depth reviews of cancer topics, and published symposium lectures are often the best overviewes available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. it is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genito urinary cancer, pediatric oncology, etc. Second, by asking eminent authori ties in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each optic and tumor type is covered in a volume appear ing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
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Taschenbuch. Condizione: Neu. Neuware - The need for adequate means by which to improve urine output is very old. Even in the 'Scuola Salernitana', the oldest medieval medical school in Western Europe, about 1000 years ago it was taught how to improve urine output. The list of known 'diuretica' included herbs, plants, roots, veg…etables, in particular asparagus, fennel and carrot. The first diuretic drugs, however, were mercurial compounds. Thus, calomel, mercurous chloride, was initially used as a diuretic in the sixteenth century by Paracelsus, being one of the ingredients of the so-called 'Guy's Hospital pill'. But calomel had a cathartic effect so that it was replaced by organic mercurial compounds. These diuretics were clearly toxic. After the discovery of the car bonic anhydrase, in the early 1930s, and the introduction of sulfanilamide as a chemotherapeutic agent, it was observed that this drug was inhibiting carbonic anhydrase in vitro and urinary acidification in vivo thereby causing metabolic acidosis; urine output, however, appeared to increase. Subsequent studies led to the synthesis of more potent analogs, in particular acetazolamide. Studies on car bonic anhydrase inhibitors led to the synthesis of benzothiadiazides which disclosed much less inactivating action on carbonic anhydrase and much more diuretic effect through an inhibition of tubular transport of sodium and chloride. Chlorothiazide was the first member of this class of diuretics. Thiazides are still used in clinical practice.
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Taschenbuch. Condizione: Neu. Neuware - The theme of this 14th International Symposium on Blood Transfusion is closely related to the work and scientific contributions of the Dutch cryobiology pioneer Dr. Herman W. Krijnen of the Dutch Red Cross Central Laboratory. Dr. Krijnen was known and respected in the national and interna…tional blood transfusion community as an extremely competent scientist and a beloved and admired colleague. Dr. Krijnen was intentionally honoured with the invitation to open this symposium on cryopreservation and low temperature biology in blood transfusion and be the guest of honour at this event. Unfortunately, Dr. Krijnen suddenly died on the first of June 1989. In honour and mem ory of Dr. Krijnen this symposium will therefore be dedicated to him. Since the lOth International Symposium on Blood Transfusion in 1985 highlighted the theme of 'Future developments in blood banking', major changes have occurred in the blood banking world. Most of these changes were forced upon the Blood Banks by the fear of spreading AIDS through contaminated donations. This not only led to the wide spread testing of blood, but also to a more appropriate counselling of the community and the blood donors in specific. Additionally, virus inacti vation techniques were introduced for those components derived from multiple donations and intended for a regular transfusion in haemophi lia patients and others.
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Taschenbuch. Condizione: Neu. Neuware - The scientists and engineers of today are relentless in their continuing study and analysis of the world about us from the microcosm to the macrocosm. A central purpose of this study is to gain sufficient scientific information and insight to enable the development of both representative a…nd useful models of the superabundance of physical processes that surround us. The engineers need these models and the associated insight in order to build the information processing systems and control systems that comprise these new and emerging technologies. Much of the early modeling work that has been done on these systems has been based on the linear time-invariant system theory and its extensive use of Fourier transform theory for both continuous and discrete systems and signals. However many of the signals arising in nature and real systems are neither stationary nor linear but tend to be concentrated in both time and frequency. Hence a new methodology is needed to take these factors properly into account.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Developments in Cardiovascular Medicine, Libro 46 di 253. Libro 46 di 253 - Developments in Cardiovascular Medicine
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Taschenbuch. Condizione: Neu. Neuware - About 2. 5 million individuals have congestive heart fai lure in the United States with over 400,000 new cases expected annually. Congestive heart failure also is one of the commonest causes for hospital admissions accounting for over 5 million hospital days per year. Despite the early rec…ognition of this condition and active medical research into both mechanisms and therapy, prognosis continues to remain dismal wi th less than a 50% expected five year survival. In the last decade we have seen many new medical and therapeutic options for patients with congestive heart failure which extend beyond the use of bed rest, sodium restriction, digitalis and diuretics. These include vasodilators of a variety of types including the angiotensin conventional enzyme (ACE) inhibitors. Also, many new inotropes are under active investigation both in oral and intravenous forms. In March of 1984 a survey of over 5000 physicians was performed under the auspices of the American Heart Association (reported in: JAOC 8:966, 1986). That survey showed that there was no universally accepted defini tion for congestive heart fai lure and that a wide spectrum of diagnostic cri teria for this common condi tion existed even among academic cardiologists. There was no clear standard as to even the mos t bas ic treatment of conges t i ve heart fai lure. For example, exercise restriction was recommended by 19% of physicians, 31% recommended no change in activity, and 50% either light exercise or an exercise conditioning program.
Lingua: Inglese
Editore: Springer Us Sep 2011 2011
Serie: Cancer Treatment and Research, Libro 25 di 180. Libro 25 di 180 - Cancer Treatment and Research
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Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelim…inary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The value of studies of monotypic populations is constantly argued in bacterial ecology. The controversy itself is evidenceofthe strong awareness that bacterial activities in natural sites are not determined by the bacteria alone.…At the same time, the best evidence that bacteria are influenced by environmental factors is the contrast between their behavior in laboratory cultures and their relatively subdued influence when in the presence of com petitors, predators, and fluctuating-often stressful-environmental conditions. Monotypic populations are admittedly reductionist, but are not therefore irrelevant to bacterial ecology. Quite the contrary. Without pure culture studies, our understanding of important and applicable bacterial activities-N fixation, for example-would still be z limited to what we could discern from a comparison of events in steamed vis-a-vis un heated soil. As was evident throughout the previous volume in this treatise, practically any method of studying natural bacterial communities upsets them while permitting only limited assessment of the respective qualities and quantitative contributions to total com munity activity of each type of bacterium present. Total activity itself is difficult to assess and is not dependably accomplished by any single method. This third volume comprises information regarding the properties of bacteria as they have been learned largely from pure culture studies. Its purpose is twofold: to provide readers with fundamental information regarding the cellular organization, physiological capabilities, and genetic systems of bacteria; and to connect known bacterial properties with environmental influences on them and with their influences on natural processes. 408 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1969 the North Atlantic Treaty Organization established the Committee on the Challenges of Modern Society. Air Pollution was from the start one of the priority problems under study within the framework of the pilot studies under…taken by this Committee. The organization of a yearly symposium dealing with air pollution modeling and its application is one of the main activities within the pilot study in relation to air pollution. After being organized for five years by the United States and for five years by the Federal Republic of Germany, Belgium, represented by the Prime Minister's Office for science Policy, became responsible in 1980 for the organization of this symposium. This volume contains the papers presented at the 14th Inter national Technical Meeting on Air Pollution Modeling and its Appli cation held in Copenhagen, Denmark, from 27th to 30th September 1983. This meeting was jointly organized by the Prime Minister's Office for Science Policy, Belgium, and the National Agency of Environmental Protection, Air Pollution Laboratory, Ris~ National Laboratory, Denmark. The conference was attended by 103 partici pants and 43 papers have been presented. The members of the se lection committee of the 14th I.T.M. were A. Berger (Chairman, Belgium), W. Klug (Federal Republic of Germany), K. Demerjian (United States of America), L. Santomauro (Italy), R. Van Dop (The Netherlands), R.E. Turner (Canada), C. De Wispelaere (Coordinator, Belgium). 836 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The foreword to the 'book of a meeting' is often an excuse for a paen of praise, a homily, or even an apologia - and sometimes a combination of all three. While certain traditions have been dispensed with in this volume the standar…d pattern for the foreword has its advantages, so here at least tradition will be adhered to - though in reverse order from that stated above. It The apologia can be dismissed briefly, for the editors have explained in their General Introduction that this is not the book of a meeting. All that remains to be added here is a description of the modus operandi. Being aware that speaking and writing are different activities requiring diffe rent presentation, each participant was asked to prepare a script for publication resembling what he would speak about only in outline. It may be that as a result the essays lack detail and are thin under some of the classical headings of scientific writing. So the reader, in turn, is asked to accept this and give his attention instead to the concepts and ideas contained therein. It may even come about that this kind of presentation will in the end result in something less ephemeral than the standard conference proceedings book. Criticism of conference proceedings and the type of meetings that give rise to these little-loved tomes is not a new phenomenom. 192 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Oilseeds and legumes provide a significant proportion of the protein and energy requirements of the world population. This important new book provides comprehensive details of the main oil seed and legume crops focusing particularl…y on the nutritional aspects of these crops which are, or have the potential to be, more widely exploited in developing countries where are or have the potential to be, more widely exploited in developing countries where protein and energy malnutrition continue to escalate. The predicted rapid rise of populations in many world regions which are increasingly vulnerable to food shortages means that a full knowledge of the nutritional significance of available crops is vital in helping to prevent potential calamities. Food and Feed from Legumes and Oil Seeds has been written by a team of international contributors, each with direct experience of these important crops and their nutritional merits, and the editors are both international experts in the crops covered. This book will become of great value to nutritionists, food and feed scientists and technologists, agricultural scientists and all those involved with overseas developments and food aid organizations. 444 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I am very happy to have this opportunity to present the work of Boris Mirkin, a distinguished Russian scholar in the areas of data analysis and decision making methodologies. The monograph is devoted entirely to clustering, a disci…pline dispersed through many theoretical and application areas, from mathematical statistics and combina torial optimization to biology, sociology and organizational structures. It compiles an immense amount of research done to date, including many original Russian de velopments never presented to the international community before (for instance, cluster-by-cluster versions of the K-Means method in Chapter 4 or uniform par titioning in Chapter 5). The author's approach, approximation clustering, allows him both to systematize a great part of the discipline and to develop many in novative methods in the framework of optimization problems. The optimization methods considered are proved to be meaningful in the contexts of data analysis and clustering. The material presented in this book is quite interesting and stimulating in paradigms, clustering and optimization. On the other hand, it has a substantial application appeal. The book will be useful both to specialists and students in the fields of data analysis and clustering as well as in biology, psychology, economics, marketing research, artificial intelligence, and other scientific disciplines. Panos Pardalos, Series Editor. 448 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The contemplation of truth and beauty is the proper object for which we were created, which calls forth the most intense desires of the soul, and of which it never tires -Hazlitt In his Nobel lecture Purcell commented that when he…saw snow in New England after the discovery of NMR, it appeared like 'heaps of protons quietly precessing in earth's magnetic field. ' If he were to make the comment in the context of how NMR is being used today, he could have conjured up an image of hydrogen, carbon, and nitrogen nuclei in proteins of an earthbound 8rganism subtly orchestrating a quiet symphony of frequencies, from 150 Hz to 2 kHz, carrying clues to the three-dimensional structure of the macromolecules. The manner in which the basic discoveries of Bloch and Purcell have led to the emergence of NMR, several decades later, as a major technique of biological and medical physics (and chemistry) is a striking example of the power of basic research. It is also a fascinating saga whereby whenever it was felt that the field had reached a plateau, new directions, new technologies, and sometimes serendipity produced new developments that revolutionized the technique and enhanced its capability. As Richard Ernst points out 'NMR is intellectually attractive, . . . the practical importance of NMR is enormous, and can justify much of the playful activities of an addicted spectroscopist' (Nobel lecture). 396 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Evolutionary Biology,ofwhichthisisthetwenty-thirdvolume,continues toofferitsreadersawiderangeoforiginalarticles,reviews,andcom mentariesonevolution,inthebroadestsenseofthatterm. Thetopicsof thereviewsrangefromanthropology,molecular…evolution,andpaleo biologytoprinciplesofsystematics. Inrecentvolumes,abroadspectrumofarticleshaveappearedon suchsubjectsasbiochemicalsystematics,comparativemorphologyand embryology,evolutionaryecology,biogeography,andpaleobiology. We havealsoattemptedtoprovideaforumforconflictingideas. Articlessuch asthese,oftentoolongforstandardjournals,arethematerialfor Evo lutionary Biology. Theeditorscontinuetosolicitmanuscriptsonaninternationalscale inanefforttoseethateveryoneofthemanyfacetsofbiologicalevolution iscovered. Manuscriptsshouldbesenttoeitherofthefollowing:Max K. Hecht,DepartmentofBiology,QueensCollegeoftheCityUniversity ofNewYork,Flushing,NewYork11367,orBruceWallace,Department ofBiology,VirginiaPolytechnicInstituteandStateUniversity,Blacks burg,Virginia24061. TheeditorswishtocongratulateDr. GhilleanT. Pranceonhisnew appointmentatKewBotanicalGardensandthankhimforhiscollabo rativeeffortsineditingthepastninevolumes. TheEditors vII Contents 1. MaintenanceofaHereditaryVirus:TheSigmaVirusin PopulationsofItsHost, Drosophila melanogaster 1 Annie Fleuriet Introduction 1 FrenchPopulationsof Drosophila melanogaster. . . . . . . . . . . 2 PolymorphismofPopulations 2 CharacteristicsofWildStrainsoftheSigmaVirus 3 EffectsoftheInfectionuponCarriers. . . . . . . . . . . . . . . . . 7 ExperimentalPopulations. . . . . . . . . . . . . . . . . . . . . . . . . . 9 MaintenanceoftheVirusinFrenchNaturalPopulations. . . 12 GeographicalVariationofthe Drosophila-SigmaSystem 14 PolymorphismofPopulations 14 ViralCharacteristics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 TentativeInterpretationoftheGeographicalPatternObserved 18 OtherSystemsofVerticallyTransmittedViruses 22 ExistenceofDifferentSensitivitiestotheVirus 22 CharacteristicsoftheViruses. . . . . . . . . . . . . . . . . . 23 MaintenanceintheVectorPopulation 24 Appendix:TransmissionofStabilizedandNonstabilized Conditions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Self-MaintenanceofStabilizedConditionthroughMaternal Lineage. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 NonstabilizedCondition . . . . . . . . . . . . . . . . . . . . . . 27 References 28 2. Domestication:EvolutionaryChangeunderStress 31 M. J. Kohane and P. A. Parsons Introduction 31 EnvironmentalChangeandDomestication 33 Ix x Contents EcologicalPhenotypes 33 BehavioralPhenotypes. . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 AdaptationtoLaboratoryConditions. . . . . . . . . . . . . . . . . . . 37 ACaseStudy:DomesticationinFoxes 41 Discussion. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 References 46 3. RangeExpansionandItsGeneticConsequencesinPopulationsof theGiantToad, Bufo marinus. . . . . . . . . . . . . . . . . . . . . . . . . 49 Simon Easteal Introduction 49 TheSpreadof Bufo marinus 50 TheIntroductions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 TheAustralianRangeExpansion 52 GeneticVariationintheIntroducedPopulations. . . . . . . . . . . 58 TheData. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 GeneticVariability. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 EffectivePopulationSize 62 Dispersal,GeneFlow,andNeighborhoodSize 63 TheGeneticEffectsofRangeExpansion 64 GeographicalPatternsofVariation 74 Conclusion 81 References 82 4. EvolutionbySocialSelection. . . . . . . . . . . . . . . . . . . . . . . . . . 85 Shozo Yokoyama Introduction 85 ConceptofSocialSelection. . . . . . . . . . . . . . . . . . . . . . . . . . 86 EvidenceforSocialSelection ; . . . . . . . . . . .
