springer us aug 2024 (24 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This protocol book presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.¿ 156 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This collection provides methods and techniques employed when culturing, manipulating, quantifying, and functionally assessing retinal ganglion cells (RGCs), vital for better understanding various ocular diseases and for developing novel therapies. The book features exhaustive and detailed protocols for the study of RGCs at both the in vitro and in vivo level, including the culture of rodent and human cells, and immunohistochemical, morphological, and functional assessments of various in vivo models of RGC death. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 208 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volumes presents current methods used in the research of schizophrenia. Chapters guide readers through molecular techniques, in vivo approaches, cell cultures and heterologous expression systems, and even research methods involving human studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Schizophrenia: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. 168 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume discusses the latest online plant genomics and cytogenetic resources used by plant evolutionary biologists and plant breeders. The chapters in this book are organized into two parts. Part One looks at plant genomic databases, and covers topics such as plant phenomics and genomics research data repositories, InpactorDB, PlanTEenrichment, and PEATmoss, among others. Part Two looks at cytogenetics and chromosome-related databases, and covers resources such as the Plant DNA C-values database, the Delphineae Chromosome Database (DCDB), B-chrom, a Database on B-chromosomes, and the Plant Ribosomal DNA Database. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective databases and offers explicit directions on how to access and get the most of these resources.Cutting-edge and comprehensive, Plant Genomic and Cytogenetic Databases is a valuable instrument for any plant science researcher who is interested in learning more about the wealth of information that is available through the use of these databases. 264 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This detailed volume provides a comprehensive set of experimental protocols and useful strategies to examine the repair of damaged bases via the Base Excision Repair (BER) pathway in vitro and in cells. Beginning with multiple molecular and cellular techniques to examine the excision of damaged bases from double-stranded DNA or DNA wrapped in a nucleosome, the book continues with sections covering procedures to detect and quantify the damaged bases, protein DNA crosslinks, and double-strand breaks, experimental procedures to identify DNA repair protein interactome by conventional tandem affinity purification followed by mass spectroscopy analysis, as well as the analysis of genome-wide binding of DNA repair proteins and copy number variations of the DNA damage response gene in tumors. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 276 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; functional and target engagement assays in cellular settings for broad characterization; and a discussion on phenotypic assays where chemogenomic sets may be applied. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides methods on the role of TLRs in immune responses and on the various approaches targeting different TLRs in cancer, autoimmunity and in vaccine development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Toll-Like Receptors: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. 300 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume details protocols for computer-assisted design and experimental characterization of RNA nanostructures. Chapters guide readers through RNA nanotechnology, design and characterization of RNA nanostructures, assessment of immunology of nanomaterials, biosensing and drug delivery, various biomedical applications, and delivery approaches for therapeutic RNA nanoparticles.¿Written in the format of the highly successful¿Methods in Molecular Biology¿series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.¿ Authoritative and cutting-edge,¿RNA Nanostructures: Design, Characterization, and Applications¿aims¿to address essential topics and concerns in the growing field of RNA nanotechnology. 348 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition volume expands on the previous edition with new discussions on the latest techniques used to study molecular chaperones and the stress response. The chapters in this book cover such as analysis of the initiation and regulation of the stress response; the role of heat shock protein 90 (Hsp90) in gene expression through chromosome-immunoprecipitation; features of chaperone function and biology; the emerging role of the extracellular HSPs; and the use of chaperones as biomarkers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 344 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides basic and state-of-the-art methods for fundamental seed research and practical application. Chapters detail recent seed dormancy studies, basic methods for germination and longevity, seed imaging, sugar, chromatin analyses, QTL analysis, and GWAS protocols for diploid and complex hexaploid species. Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge,Seed Dormancy: Methods and Protocols aims to ensure successful results in the further study of this vital field. 208 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph is written based on the author's extensive research over the last decade on the assessment and control of cracking of early-age concrete. The technique of crack control of modern concrete at early age is further developed through experimental and theoretical research, such as mitigating the drop of IRH, controlling the hydration process, decreasing the shrinkage, and increasing the tensile strength. It indicates the innovative findings and establishes prediction models on early-age internal relative humidity, autogenous shrinkage, tensile creep of modern concrete considering water-to-cement ratio, curing temperature., etc; reveals the variation law and mechanism of early-age cracking resistance of modern concrete with different kinds of fibers, supplementary cementitious materials, chemical admixtures, and internal curing agents under circumferential or uniaxial restrained condition. It is designed as a reference work for professionals or practitioners and a textbookfor undergraduates or postgraduates. 439 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This detailed volume explores experimental laboratory procedures for a wide range of steroid bioconversions. After an overview on the current trends and perspectives, the book continues with sections covering microbial screening and synthetic biology applied to microorganisms able to catabolize sterols, methods on strain characterization, including omics and biochemical analyses, methods of fermentation and biocatalysis for steroids production, as well as a chapter on the medical use of glucocorticoids in cancer patients. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 372 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This third edition expands on the previous editions with updated and new chapters on protein chromatography. Chapters detail protein stability and storage, avoiding proteolysis, protein quantitation methods, generation and purification of recombinant proteins, recombinant antibody production, and the tagging of proteins. Written in the format of the highly successfulMethods in Molecular Biologyseries, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.Authoritative and cutting-edge,Protein Chromatography: Methods and Protocols, Third Edition aims to provide commonly used methods and new approaches to help both new researchers and experts expand their knowledge. 508 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume looks at the latest methods used to study imaging techniques, metabolic tracing, and deep muscle phenotyping. The chapters in this book cover topics such as imaging skeletal muscle mass using MRI, dual-energy x-ray absorptiometry, CT, and ultrasound; measures of neuromuscular function such as power/strength/force; microscopy and immunohistochemistry; and ex vivo fibre function and isolation. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and thorough, Neuromuscular Assessments of Form and Function is a valuable resource for researchers interested in multiple methods used to study skeletal muscle neurophysiology. 318 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume covers the latest advancements in the study of lipid signaling. The chapters in this book cover topics such as neuronal cells such as retinal ganglion cells, microglial cells to muscle, and epithelial cells; extraction for signaling studies, including clinical studies in humans; and discussions on different cells, tissues, and diseases like Alzheimer's disease, musculoskeletal diseases, eye diseases, and metabolic diseases. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and comprehensive, Lipid Signaling: Methods and Protocols is a valuable resource for researchers looking to expand their knowledge of this important and developing field. 280 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume looks at the latest methodological developments used in the field to investigate the synaptic organization of the brain from different viewpoints including structural, structural/functional, molecular, and computational methods. The chapters in this book are organized into five parts and cover topics such as preparation of brain tissue and techniques; connectivity; synaptic vesicles; phenomenological modeling; and dendritic spines. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.Authoritative and thorough, New Aspects in Analyzing the Synaptic Organization of the Brain is a valuable resource that will help students, post-docs, and even expert researchers learn more about the discipline of cellular and synaptic neuroscience. 452 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition details new and updated protocols for experimental approaches that are currently used to study the formation of flowers. Chapters guide readers on genetic methods, phenotypic analyses, genome-wide experiments, modeling, and system-wide approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Flower Development: Methods and Protocols, Second Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. 604 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes the basic concepts and recent advances in new discoveries and technologies related to microbial omics and their role in environmental research and human health. The term 'omics' refers to a blend of high-throughput analysis and traditional methods including genomics, transcriptomics, proteomics, lipidomics and metabolomics for a variety of applications in the field of life sciences, biomedical sciences, environmental sciences, and related industries. The book aims to fill the existing gap in terms of a comprehensive approach that incorporates recent advances in this dynamic field and provides an answer to why this field requires an interdisciplinary research approach.The focus of this book is on the applications of genomics, epigenomics, metagenomics, integrative omics, machine learning and microbiome research in environmental health, disease, wastewater epidemiology, antibiotic resistance, drug discovery, cancer, production of secondary metabolites of microbial origin, oxidative stress alleviating mechanisms, etc. The overall construction of this book emphasizes three major perspectives, namely, elaborate knowledge from fundamentals to recent advances in technologies about omics in general and its application in microbiology, environment, and health in particular; illustrative figures capable of easy visualization of complex pathways; and serving as a platform for highly demanded bioinformatics strategies including relevant codes, programming scripts, machine learning and use of artificial intelligence strategies needed to streamline the research outcomes. With global contributions from authors from internationally renowned organizations who excel in relevant research, this book will benefit bibliophiles and prospective audiences from the research fraternity, academia, professionals, and experts in the field of life sciences, biomedical as well as industries related to the development of drug design and novel advances in biotechnological applications. 415 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume brings together theoretical, experiential, and creative perspectives on the phenomenon of urban foraging. In a rapidly urbanising world, foraging is (re)raining popularity as a way to connect with nature and cope with uncertainty. Authors from various disciplines and geographies make sense of what this means for humanity.Urban foraging represents a multifaceted movement that provides people with avenues for sustenance, socialising, and spirituality. Motivations and implications of urban foraging vary across the socioeconomic spectrum, as do barriers and enablers. Urban foraging can help people adapt to change, and build resilience to shocks, but its spontaneous and unregulated nature makes it attractive to many. Recognising and promoting sustainable urban foraging therefore is a delicate balancing act. This collection discusses the philosophical and practical considerations towards this aim.The book is of interest to researchers, practitioners, entrepreneurs, and creatives, inviting readers to envisage scenarios that are desirable and achievable. It is of special interest to those working in urban and landscape planning, social-ecological systems, non-government organisations, municipal and development corporations, and the environment. 426 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides protocols and techniques to study metastatic dormant cells. Chapters focus on in vitro systems to model metastatic dormancy in vitro, detection of disseminated tumor cells in vivo, perturbation of key molecules involved in metastatic dormancy, and clinical features of delayed metastatic relapses of specific tumor types.Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge,Cancer Cell Dormancy: Methods and Protocolsaims to ensure successful results in the further study of this vital field. 236 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Language, as a system we use to communicate, represents the brain¿s biologically perfected machinery for converting thoughts (ideas, concepts, and reflections of both the outside world and our inner feelings) into words and sentences. Crucially, this process occurs in real time. How hundreds of billions of neurons within the dark of the skull control language and speech remains, in some respects, a mystery. To track such neural dynamics in time, we need to exploit physiological tools capable of following temporal patterns of neural activity on a fine-grain time scale. In parallel, it is necessary to begin to provide a real interdisciplinary academic background for scholars wishing to embark on this field of study. Unlike many similar efforts, this book has been conceived as a hands-on tool offering the reader the possibility to progressively acquire principles, techniques, and methods necessary to pursue interdisciplinary research in a fascinating field intersecting linguistic andneuroscience. It focuses on neurophysiological methods and applications useful to track the high speed and rapid temporal dynamics of neural activity involved in language and speech. The chapters in this book are organized into four parts. Part One discusses neural principles and tools for an effective approach to the field of investigation. Part Two looks at the issues and perspectives concerned with the use of a range of neurophysiological technologies to investigate the neural computations of language and speech processes. Part Three focuses on an in-depth exploration of the neural processes associated with the main types of linguistic information, ranging from phonemes and prosody to syntax, pragmatics, and figurative language. Lastly, Part Five explores the phenomena that goes beyond the segments of basic linguistic units. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory 820 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Language, as a system we use to communicate, represents the brain¿s biologically perfected machinery for converting thoughts (ideas, concepts, and reflections of both the outside world and our inner feelings) into words and sentences. Crucially, this process occurs in real time. How hundreds of billions of neurons within the dark of the skull control language and speech remains, in some respects, a mystery. To track such neural dynamics in time, we need to exploit physiological tools capable of following temporal patterns of neural activity on a fine-grain time scale. In parallel, it is necessary to begin to provide a real interdisciplinary academic background for scholars wishing to embark on this field of study. Unlike many similar efforts, this book has been conceived as a hands-on tool offering the reader the possibility to progressively acquire principles, techniques, and methods necessary to pursue interdisciplinary research in a fascinating field intersecting linguistic andneuroscience. It focuses on neurophysiological methods and applications useful to track the high speed and rapid temporal dynamics of neural activity involved in language and speech. The chapters in this book are organized into four parts. Part One discusses neural principles and tools for an effective approach to the field of investigation. Part Two looks at the issues and perspectives concerned with the use of a range of neurophysiological technologies to investigate the neural computations of language and speech processes. Part Three focuses on an in-depth exploration of the neural processes associated with the main types of linguistic information, ranging from phonemes and prosody to syntax, pragmatics, and figurative language. Lastly, Part Five explores the phenomena that goes beyond the segments of basic linguistic units. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratoryLibri GmbH, Europaallee 1, 36244 Bad Hersfeld 820 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This handbook covers both principal and applications aspects of hydroponics. This reference book shows the state-of-the-art in this area, while offering a clear view of supplying plants with nutrients other than soil. Chapters about hydroponics provides the reader with an understanding of the properties of the various soilless media and how these properties affect plant performance in relation to basic agricultural operations, such as fertilization and irrigation. Chapters explore the drawbacks and advantages of using hydroponics as a soilless crop production system and provide a wider view of science, technology, and economic impact of hydroponics.This book is a valuable resource to agriculturists, horticulturalists, greenhouse and nursery managers, and professionals involved with the production of plants. The handbook provides chapters about technology and applications of hydroponics. It contains an overview of the relevance of aquaponics in the fulfillment of the SDGs. 404 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This handbook covers both principal and applications aspects of hydroponics. This reference book shows the state-of-the-art in this area, while offering a clear view of supplying plants with nutrients other than soil. Chapters about hydroponics provides the reader with an understanding of the properties of the various soilless media and how these properties affect plant performance in relation to basic agricultural operations, such as fertilization and irrigation. Chapters explore the drawbacks and advantages of using hydroponics as a soilless crop production system and provide a wider view of science, technology, and economic impact of hydroponics.This book is a valuable resource to agriculturists, horticulturalists, greenhouse and nursery managers, and professionals involved with the production of plants. The handbook provides chapters about technology and applications of hydroponics. It contains an overview of the relevance of aquaponics in the fulfillment of the SDGs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 404 pp. Englisch.