springer us chapman and hall crc jan 2013 (27 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Neurochemistry, having the objective of elucidating biochemical processes subserving nervous activity, emerged as an application of chemistry to the of neurobiological problems as a post-World War II phenomenon. investigation However, only in the last 40 years has the chemical community recognized neurochemistry as a distinct, if hybrid, discipline. During this period great strides have been made. However, recently neurochemistry, along with neu rophysiology, neuropharmacology, neuroanatomy, and the behavioral sci ences, has emerged to form neuroscience, a new community of scientists with its own national society, journals, and meetings. Actually, this recently formed hybrid, neuroscience, is in the process of merging with another well-established discipline, molecular genetics (frequently called molecular biology, and itself a hybrid), which appears to have sufficient hybrid vigor to form yet a new community of scientists, which, for want of a more imaginative term, has been called molecular genetic neuroscience. Clearly, advantages resulting from such mergers or hybridizations accrue not only from the merging discipline (neurochemistry in this case) to the new community (molecular genetic neuroscience), but also in the reverse direction. This Foreword will be concerned primarily with examples of this latter process. 736 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The distinction between molecular immunology and immunobiology is neces sarily arbitrary. The most rapid progress is usually made in the blurred area between the two, when the chemist is aware of the full significance of the biological problems, and the biologist is alert to the contribution that a knowl edge of molecular structure can be made to their solution. The range of scientific disciplines able to contribute to research in immunology, which this approach brings, is reflected in the present volume. Protein chemists worked out the arrangement of the polypeptide chains and the amino acid sequences of antibodies and X-ray crystallographers the three dimensional structure, but more precise definition of the amino acid side chain positions in the combining site is required for an understanding of the subtleties of antibody specificity. That this can be achieved with physical techniques such as nuclear magnetic resonance has been shown by R. A. Dwek, and in his chapter he summarizes these results with a minimum of technical detail. The immune response has been shown to be dependent on complex cellular interactions and further progress will be facilitated by investigation of the molecular basis of these interactions. This necessitates study of the structure and organization of the molecules in the surfaces of lymphocytes and other cells. 272 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the first book that is devoted entirely to a discussion of the effects on drinking behavior of sensory stimulation of the tongue and mouth. As Blass and Hall (J 976) have recently pointed out, there has been an overrejection of the emphasis by Cannon (1932) and Hull (1943) on the peripheral origins (e. g. , dry mouth, empty stomach) of the control of ingestive behavior. Thus most present-day investigators of drinking behavior have been concentrat ing on central mechanisms of control, to the neglect of the periphery. In this volume we have attempted to bring together much of the pertinent 'peripheral' literature through originally written chapters that are concerned with the role of orosensory factors in the mediation of drinking and licking. Postingestive effects of fluids receive little attention. Indeed, two chapters deal with consummatory licking in the absence of intake of fluids. A good understanding of the consequences of orosensory stimulation on licking and drinking behavior requires insight into the functional anatomy of the tongue and mouth, the characteristics of the licking response and the problem of recording of licking behavior. Several chapters deal with these subjects. It has not only been a pleasure but also a privilege to edit this volume. We have learned much from the expert treatment of the different aspects of licking and drinking behavior by the chapters' authors. 440 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Interest in biological rhythms has been traced back more than 2,500]ears to Archilochus, the Greek poet, who in one of his fragments suggests ',(i,(VWO'KE o'olos pv{}J.tos txv{}pW7rOVS ~XH' (recognize what rhythm governs man) (Aschoff, 1974). Reference can also be made to the French student of medicine J. J. Virey who, in his thesis of 1814, used for the first time the expression 'horloge vivante' (living clock) to describe daily rhythms and to D. C. W. Hufeland (1779) who called the 24-hour period the unit of our natural chronology. However, it was not until the 1930s that real progress was made in the analysis of biological rhythms; and Erwin Bunning was encouraged to publish the first, and still not outdated, monograph in the field in 1958. Two years later, in the middle of exciting discoveries, we took a breather at the Cold Spring Harbor Symposium on Biological Clocks. Its survey on rules considered valid at that time, and Pittendrigh's anticipating view on the temporal organization of living systems, made it a milestone on our way from a more formalistic description of biological rhythms to the understanding of their structural and physiological basis. 588 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -HAROLD B. GERARD AND NORMAN MILLER In the fall of 1965, when the school board of the Riverside Unified School District made its momentous decision to desegregate the ele mentary schools in Riverside, both of us were faculty members in the psychology department on the Riverside campus of the University of California. The riots in Watts had occurred the previous August and the shock waves were being felt around the cou~try. Although the black population of Riverside at the time was only 6% or 7%, people were ap prehensive. A story appeared in the local paper, The Rzverside Press Enterprzse, about several Blacks who were watching the burning and looting in Watts on TV. One of them, excited by what he saw, ex claimed, 'Man-let's burn here, too. ' The others in the bar were more level-headed and fortunately dissuaded him from following his impulse. Barely two weeks later, however, someone set fire to one of the build ings of Lowell School, in the eastside ghetto area. Nothing was left of the building but a charred shell. People in Riverside, of all ethnic groups, were generally edgy in the face of a seemingly volatile situation. Agitation by minority parents for improved education for their children seemed to be reinforced by the general unrest. 328 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The primary purpose of this book is to bring to the attention of members of the medical and scientific communities, as well as to other interested persons, a new and expanding area of investigation that features the use of chemicals for the prevention of tumor induction and development. This novel use of chemical compounds has succeeded in producing a remarkable series of discoveries in recent years. Some of these are beginning to be evaluated in the field of clinical oncology in a manner that has potentially enormous public health implications. It is anticipated, therefore, that increasing amounts of time, energy, and financial resources will be devoted to the further development and expansion of this work. The major contribution of this book at the present time is that it summarizes and brings up to date the pioneering efforts of the various scientists who originated this new and exciting field of scientific activity. The thoughts expressed by Louis Pasteur in 1884 may soon be applicable in the fight against cancer: 'When meditating over a disease, I never think of finding a remedy for it, but instead a means of preventing it. ' The emphasis on cancer prevention currently underway is the result, in part, of an increased awareness that the environment-geographical, cultural, and occupational-has a role in development of the disease. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Radiography, the use of penetrating radiation to produce shadow images of the internal structure of materials, has been with us since Roentgen made his discovery of x rays in 1895. However, applications of radiography in the earth sciences and in the related field of soils engineering have, until recent ly, been slow to develop. Bruhl reported optimistically on applications in paleontology as early as 1896 and there have been additional reports through the years. However, very few paleontologists adopted the method and the significant literature is relatively restricted. In soil mechanics, Gerber observed the movement oflead pellets in sand during a plate-bearing test as early as 1929. Gradual ly, radiography was applied to other tests including those on footings, compaction of soils, strain in sand, effects of pile penetration, and displace ments under moving wheel loads. Recently, such work has broadened into much varied and sophisticated research. Applications in geology may be dated to Hamblin's work on rocks re ported in 1962. His demonstration that many fine textural and structural details can be observed in slices of rock led to experimentation by others on unconsolidated sediments and soils. Work is now expanding at an un precedented rate. In some operations, such as the logging of oceanographic cores, it is already a routine process. The advantages of radiography lie in its nondestructive nature and its ability to reveal features that sometimes cannot be seen in any other way. 172 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The third annual International Industrialization Symposium on the SuperCollider, IISSC-held March 13-15, 1991, in Atlanta, Ga.-was an enormous success. The number of attendees, exhibitors, and representatives from foreign countries surpassed the totals of previous years. There were 740 attendees, representing more than 2 dozen universities and colleges, 32 states, 9 national labs, 6 research centers, several government entities at the local, state, and federal level, 182 businesses & industry and 14 countries. More than 100 exhibits, sponsored by 85 organizations, added to the excitement. 'Getting Down to Business' was the theme of this year's Symposium. The fact that the Superconducting SuperCollider (SSC) is indeed underway was the message delivered by the Symposium's keynote speaker, Dr. Roy Schwitters, and expanded upon by the opening plenary speakers. The project is moving from the planning stage to actual construction, to development and procurement of equipment, and to resolution of the technical issues involved in advancing the state-of-the-art in areas such as theory, controls, systems, metallurgy, quality control, management, cryogenics, power systems, detectors, interagency cooperation and funding. Plenary speakers included: Paul Gilbert, Chairman of Parsons Brinckerhoff Quade & Douglas, Inc. 1256 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The stream of our consciousness contains an almost unceasing parade of sensation-like experiences, even in the absence of any external stimulation to produce them. We experience picture-like things, sound-like things, and more; our experiences can resemble any of our sense modalities. These experiences are what we refer to by the phrase 'mental imagery.' The images need not be vivid. People who doubt that they experience visual imagery are often persuaded by a simple exercise: count the windows of the house in which you live. Nearly everyone performs this task by walking around the house in imagination while counting windows, or by walking through the house counting them from the inside. The imaginary windows seem to be set in visual space. There is a temptation to point at them with an index finger while one counts, even though the images may never become vivid enough to seem like an actual visual experience. But if they seem set in visual space, if they can be pointed at, they clearly constitute a sensory-like experience in some meaningful way. 412 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Growth, as we conceive it, is the study of change in an organism not yet mature. Differential growth creates form: external form through growth rates which vary from one part of the body to another and one tissue to another; and internal form through the series of time-entrained events which build up in each cell the special ized complexity of its particular function. We make no distinction, then, between growth and development, and if we have not included accounts of differentiation it is simply because we had to draw a quite arbitrary line somewhere. It is only rather recently that those involved in pediatrics and child health have come to realize that growth is the basic science peculiar to their art. It is a science which uses and incorporates the traditional disciplines of anatomy, physiology, biophysics, biochemistry, and biology. It is indeed apart ofbiology, and the study of human growth is a part of the curriculum of the rejuvenated science of Human Biology. What growth is not is aseries of charts of height and weight. Growth standards are useful and necessary, and their construction is by no means void of intellectualchallenge. Theyare a basic instrument in pediatric epidemiology. But they do not appear in this book, any more than clinical accounts of growth disorders. This appears to be the first large handbook-in three volumes-devoted to Human Growth. Smaller textbooks on the subject began to appear in the late nineteenth century, some written by pediatricians and some by anthropologists. 656 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Enzyme technology continues to maintain a high degree of interest both in the academic and industrial communities. Since the last Enzyme Engineering Conference held in Bad Neuenahr, Federal Republic of Germany, two years ago, an increasing emphasis has been placed on the study and application of immobilized whole cells and organelles. This new emphasis has been reflected in the number of presentations directed to this area. The Fifth International Enzyme Engineering Conference was held in Henniker, New Hampshire, July 29 to August 3, 1979. The organizers of this conference are especially grateful for the generous support received from a number of industrial organizations. The conference was attended by 183 participants representing over 22 countries making this truly an international conference. During this conference, emphasis was placed on a wide variety of areas including: enzyme production, energy transduction, co factor modification, biomass conversion, immobilized enzymes, cells and organelles, and enzymatic synthesis of chemicals and pharma ceuticals. This volume contains most of the presentations and posters presented at the Fifth Conference. The names of the session co chairmen, workshop chairmen, committee members and sponsoring organizations are included as an appreciation of their efforts in making this a successful conference. The preparation of this volume was carried out by the editors including editing and proofing of the individual manuscripts and the final copy of this volume. The editors are indebted to Ms. S. 504 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Information systems science is advancing in various directions with rapid strides. Many diversified ideas and methodologies have been revised and extended. Numerous new techniques and approaches have been con ceived and developed. Some recent advances are covered in this series. The fourth volume of this series provides in-depth discussions of some newly developed theories and techniques concerning computer language-level augmentation, time-sharing systems, text editing systems, grammars and automata, and error correcting codes in computer arithmetic. In Chapter 1, V. K. Smirnov presents an authoritative review of the augmentation of machine language level. He discusses the effects of ex tension of computer functions upon machine language and the influence of development of software systems upon the augmentation of computer language level. Some specific ways of augmenting the machine language level are examined. The problem of information organization, storage, search, and retrieval in a computer is studied. The introduction of higher-level languages has stimulated widespread applications of computers. Formal language theory has been recognized as a topic offundamental importance in the study of information systems science. In Chapter 2, M. A. Harrison examines the phrase-structure grammars, the right linear grammars, the context-free grammars, the LR(k) grammars, and the context-sensitive grammars. The author discusses the relations between mathematical models of computers and a family of formal lan guages. The language theory may stimulate new ideas for the augmentation of machine language level. 348 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Section VIII: Research Procedures and Data Analysis.- 1 Techniques for Cytogenetic Analysis.- 2 Mutation Testing Systems.- 3 Cell, Tissue, and Organ Culture as Teratologic Tools.- 4 Whole Embryo Explants and Transplants.- 5 Survey of in Vitro Systems: Their Potential Use in Teratogenicity Screening.- 6 The Structure and Uses of Genetically Homogeneous Lines of Animals.- 7 Multigeneration Reproduction Studies.- 8 The Design of Subprimate Animal Studies.- 9 Feasibility and Design of Subhuman Primate Studies.- 10 Uterine Vascular Interruption and Combined Radiation and Surgical Procedures.- 11 Analytical Techniques for the Study of Teratogenic Mechanisms.- 12 Immunological Aspects of Development.- 13 Behavioral Teratology.- 14 Methods and Concepts of Biometrics Applied to Teratology.- of the Complete Handbook (Volumes 1¿4). 472 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aging is one of the most serious and costly health problems in the Western world. A disproportionate amount of the available health care capability is devoted to the health care of the aged and the cost of this care is soaring. Viewed in wide perspective, aging presents two problems for the researcher's consideration. First is that of providing the most efficacious therapeutic regi mens and the best possible care for those already in their latter years. The second is to determine the cause or causes for senes cence and all its attendant problems in order to decrease the im pact of senescence on general health and well being. This volume is aimed at examining possible relationships be tween biological time structure and aging and ways by which these interrelationships might be examined in terms of both the causes of senescence and the management of health problems of the elderly. The purpose of the volume is to stir the interests of chronobiolo gists in gerontology and those of gerontologists and geriatricians in chronobiology. 356 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This has been a year of substantial change for The Year in Endocrinology. The first change, though perhaps only a semantic one, nevertheless represents a landmark. Although last year's volume was designated as the first of an annual series, that seemed to me at the time merely a hope-a realistic hope, perhaps, but a hope, nevertheless. With the publication of this year's volume, however, this can accurately be said to be an annual series, one that we trust will fulfill a need and will therefore continue for years to come. Among other changes from last year's volume are some that were originally intended and others that were unintended. In the former category is the substitution of a chapter on water metabolism and vaso pressin, excellently prepared by Dr. Gary L. Robertson, for the chapter on paraendocrine syndromes that appeared last year. Chapters on these two topics will continue to appear on alternate years. Obviously, the non recurring chapter on a topic of special interest has also changed, and this year's comprises a comprehensive review of autoimmune endocrine dis ease by Drs. Jay Silverberg and Robert Volpe. The unexpected change results from the inability of Dr. Louis Avioli to continue as a member of the Editorial Board. Most fortunately, however, we have persuaded Dr. Charles R. Kleeman to join the Board and to be responsible for the chapter on the parathyroid gland and mineral metabolism. Dr. Kleeman has been assisted on the preparation of this chapter by his daughter, Dr. 420 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The subject of this book is neuroendocrinology, that branch of biological science devoted to the interactions between the two major integrative organ systems of animals-the endocrine and nervous systems. Although this science today reflects a fusion of endocrinology and neurobiology, this synthetic ap proach is relatively recent. At the beginning of the 20th century, when the British physiologists, Bayliss and Starling, first proposed endocrinology to be an independent field of inquiry, they went to great lengths to establish the autonomy of chemical secretions in general and their independence from nervous control in particular (Bayliss, W. M. , and Starling, E. H. , 1902, The mechanism of pancreatic secretion,]. Physiol. 28:325). They argued with Pav lov, who said that there was a strong influence of the nervous system on the gastrointestinal phenomena the endocrinologists were studying. For several decades, the English physiologists prevailed, at least in the West; and Pavlov's critique was not taken to heart by the practitioners of the newly emerging discipline of endocrinology. Through the work of Harris, the Scharrers, Sawyer, Everett, and others, there has been something of a scientific detente in the latter half of this century; the hybrid field of neuroendocrinology is now regarded as one of the corner stones of modern neural science and is of fundamental importance in basic and clinical endocrinology. 588 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Those who are familiar with the two volumes of The Year in Endocrinology may, at first glance, fail to recognize their relationship to the present volume, Contemporary Endocrinology. The name is different and the cover design different, but nonetheless the admonition against judging a book by its cover is very well taken in this instance. In fact, Contemporary Endocrinology is not only the direct linear descendant of The Year in Endocrinology, it is a purposeful clone thereof-the topics are unchanged, the talented group of authors is unchanged, and most importantly, both the objective of the work and the manner in which that objective is approached are unchanged. The objective is, of course, to assist the reader in maintaining currency with respect to important developments, both basic and clinical, in the major areas of endocrinology. We are all much too familiar, unfortunately, with the difficulty of maintaining currency these days. Our approach to dealing with the informational inflation that we are suffering is similar to that used by economists in dealing with monetary inflation, that is, to increase interest. This we have attempted to do by providing for the reader an easy-to-read group of essays in which advances in individual areas of endocrinology are re viewed broadly, synthesized, and placed into perspective by a group of authors who are authorities in their individual fields. They serve, not as guest artists, but as members of a stable Editorial Board that provides continuity by contributing to successive volumes. 420 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is concerned with metabolic reactions occurring in the nervous system. Some time ago, it was thought that since most of the intermediary metabolism that can be observed in the brain is not specific to this organ, there is little justification in studying neural metabolism as such. Later it was realized that for an understanding of neural functions, the understanding of metabolism in the brain and its alterations is essential. All aspects of the metabolism of a substrate in brain, or all metabolic reactions of the nervous system, could not be included in this volume; some will be dealt with in other volumes (such as the ones covering metabolic turn over, alterations of metabolism, or pathology). Review of the aspects covered here clearly shows that the study of metabolic reactions in the nervous system is a very active field, producing important results. As in so many areas of research, as we learn more, new aspects become known, new questions emerge, and we see that in solving some problems we open areas with many additional problems to solve. But the accomplishments to date are impressive and indicate further important advances in the future. Brain metabolism is more active, more plastic, and more comprehensive than previously estimated. It is an essential part of brain function, and with its alteration, brain function will be altered. This shows the importance of more knowledge in this area. It is hoped that this volume will be of assistance in such further studies. 728 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as well as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that by presenting information concerning these apparently heterogeneous topics under the unifying umbrella of the RES attention will be focused on the similarities as well as interactions among the cell types constitut ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloendothe lial Societies. 788 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Rapid advances in knowledge have led to an increasing interest in neuro biology over the last several years. These advances have been made possible, at least in part, by the use of increasingly sophisticated methodology. Furthermore, research in the most rapidly advancing areas is essentially multidisciplinary and is characterized by contributions from many investi gators employing a variety of techniques. While a grasp of fundamental neurobiological concepts is an obvious prerequisite for those who wish to follow or participate in this field, critical awareness and evaluation of neurobiological research also requires an understanding of sophisticated methodologies. The objective of Methods in Neurobiology is the development of such critical abilities. The reader is exposed to the basic concepts, principles, and instrumentation of key methodologies, and the application of each meth odology is placed in the special context of neurobiological research. The reader will gain familiarity with the terminology and procedures of each method and the ability to evaluate results in light of the particular features of neurobiological preparations and applications. 616 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These proceedings report the lectures and seminars presented at the NATO Advanced Study Institute on 'Optical Properties of Ions in Solids,' held at Erice, Italy, June 6-21, 1974. The Institute was the first activity of the International School of Atomic and Molecular Spectroscopy of the 'Ettore Majorana' Centre for Scientific Culture. The Institute consisted of a series of lectures on optical properties of ions in solids that, starting at a fundamental level, finally reached the current level of research. The sequence of lectures and the organization of the material taught were in keeping with a didactical presentation. In essence the Institute had the two-fold purpose of organizing what was known on the subject, and updating the knowledge in the field. Fif'teen series of lectures for a total of 44 hours were given. Five one-hour seminars and five twenty-minute seminars were presented. A total of 57 participants came from 40 laboratories in the following countries: Belgium, Canada, France, Germany, Ireland, Israel, Italy, Netherlands; Polatid, Romania, Switzerland, the United Ki~gdom, and the United States. The secretaries of the Institute were: D. Pacheco for the scientific aspects and A. La Francesca for the administrative aspects of the meeting. These proceedings report the lectures, the one-hour seminars (abstracts only) and the twenty-minute- seminars (titles only). The proceedings report also the contributions sent by Prof. K. Rebane and Dr. L. A. Rebane who, unfortunately, were not able to come. 512 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The content of Volume 8 of the Handbook of Neurochemistry is a perfect example and sample of what occupies neurochemists in the late 1980s. What occupies them are questions, concepts, and technology that either did not start with the nervous system, or rapidly moved out of its exclusivity (see, for in stance, chapters on neurotensin, beta-lipotropin, behavioral and neurochemical effects of ACTH, cholecystokinin, etc.). Thus, the neurochemist is more and more seen as a biochemist occupied by questions, concepts, and technology that are not unique to the nervous system, even though the ultimate substrate of these questions, as well as the ultimate functions so studied and occasionally explained, are of the nervous system. Look at the case of the hypothalamic hypophysiotropic peptides, also called hypothalamic releasing factors, or hypothalamic releasing hormones. These are all small-to-medium-size polypeptides originally characterized in ex tracts of the hypothalamus on the basis of bioassays directed at studying their effects on one or another of the secretions of the adenohypophysis. We know now that TRFs (See Chapter 8), the thyrotropin and prolactin releasing factor, somatostatin, the hypothalamic inhibitor of the secretion of growth hormone, as well as LRF, the hypothalamic decapeptide stimulating the secretion of pituitary gonadotropins, are to be found in parts of the brain other than the hypothalamus, where their function is obviously not hypophysiotropic. Such is also the case for CRF-the corticotropin and beta-endorphin releasing factor. 704 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -THE PHYSICAL BASIS FOR HETEROGENEOUS CATALYSIS is the proceedings of the ninth Battelle Colloquium in the Materials Sciences, held in Gstaad, Switzerland, September 2-6, 1974. It took as its theme the application of modern theoretical and experimental surface physics to heterogeneous catalysis. Progress in the field by classical chemical methods seemed to have slowed down, at a time when the need for better catalysts was particularly great. The Organizing Committee thought it might be possible to accelerate progress by the application of the powerful techniques evolved in recent years for studying atomically clean surfaces. However, the translation of ideas derived from clean single crystal surfaces with well characterized chemisorbed layers to real catalysts with high ratios of surface to mass on which reactions were taking place and requiring transport of mass and energy is a giant step, raising many questions and requiring thorough discussion by surface physicists on the one hand and catalytic chemists on the other. The 1974 Battelle Colloquium provided a forum for this exchange. As its usual custom, the Colloquium started the first day of introduc tory lectures by three distinguished scientists who have contributed impor tantly over many years to this field. 628 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The covalent attachment to deoxyribonucleic acid in vivo of a large number of different types of chemical compounds (both normal cellular constituents such as proteins and amino acids, and also exogenous compounds such as drugs, carcinogens, etc. ) have been shown to exert profound effects upon cells. Four research activi ties, formerly considered to be totally independent, relate to this problem of nucleic acid adducts--(1) normal covalent attachment of DNA to membranes, protein linkers in chromosomes, etc. ; (2) the roles of radiation and chemical enhancement of DNA adduct formation in cell killing and mutagenesis. (A related field is the use of known cross-linking reactions to gain information on structural associations in macromolecular complexes. ); (3) the relevance of DNA adducts to chemical and radiation carcinogenesis; (4) the rele vance of DNA adducts to the cross-linking theory of cellular aging. (1) There are numerous examples of normal linkages between DNA and protein, e. g. , DNA-membrane attachment sites, protein linkers in chromosomes, amino acids covalently linked to DNA as a function of growth conditions, and gene regulation by non-covalently bound proteins. A summary of data on natural adducts to DNA thus serves to introduce the subject of the radiation and chemical enhancement of DNA adduct formation. (2) In the past, radiation biology has been concerned mainly with trying to understand the radiation chemistry of purified DNA, and the biological effects and repair of these radiation-induced alterations when produced in cellular DNA. 576 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In August 1978 a group of 80 physicists from 51 laboratories of 15 countries met in Erice to attend the 16th Course of the International School of Subnuclear Physics. The countries represented at the School were: Austria, Denmark, Federal Republic of Germany, Finland, France, Israel, Italy, the Netherlands, Sweden, Switzerland, South Africa, Turkey, the United Kingdom, The United States of America, and Yugoslavia. The School was sponsored by the Italian Ministry of Public Education (MPI) , the Italian Ministry of Scientific and Technological Research (MRSI) , the North Atlantic Treaty Organization (NATO), the Sicilian Regional Government, and the Weizmann Institute of Science. As usual, the Course was devoted to a review of the most out standing problems and results in Subnuclear Physics, with particular emphasis on the new aspects; there were mainly two: supersymmetry and electroweak interactions. In his famous lecture at Erice in 1967, Sid Coleman reviewed 'All possible symmetries of the S matrix. ' All but one, namely that which tells you: if you have a fermion you must have a boson. This is super symmetry , and this produces the superspace, i. e. an entity which has not only the Einstein-'bosonic' coordinates, but also 'fermionic' coordinates. From superspace we get supergravity; and this means that one day we should be able to detect not only the graviton (with spin 2) but also the gravitino (spin 3/2). If we add 'flavour', 'colour', and 'family' as other intrinsic degrees of freedom, we get extended supergravity. 816 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the proceedings of a NATO Advanced Study Institute devoted to the study of dynamical correlation functions of the form (I) J~e-lwt 6ft T- is an equilibrium average. In equation (1) it is useful to regard the product AB as the product of two operators in cases in which A and B refer to different spatial points in a condensed matter sys tem and/or in which A and B behave dynamically in a quasiharmonic way. In the second case, one has a two quasiparticle correlation function and CAB;AB(w) gives information about quasiparticle inter actions. Condensed matter physics has increasingly turned its attention to correlation functions of this type during the last 15 years, partly because the two point and/or one-particle correlation functions have by now been very thoroughly studied in many cases. The study of four point and/or two quasiparticle correlations has proceeded somewhat independently in several diverse fields of condensed matter physics and it was one purpose of the institute to bring experts from these different fields together to describe the current state of their art to each other and to advanced students. 680 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I do not think of myself as primarily interested in method, but in the substance of psychology. Nevertheless, our discipline has such difficulties in coming to grips with its substance that I have found myself getting involved in fww to do it persistently and since the beginning of my career. That career has been divided between diagnosis and research, the balance between them swinging gradually from the former to the latter. To the astonishment of many of my students and colleagues, I have never become a psychotherapist nor a psychoanalyst, though I have looked closely over the shoulders of many friends at their work, have attended continuous case seminars, and have participated in research on psychotherapy and psychoanalysis enough to feel that I have a pretty good grasp of what that kind of endeavor is like. So I have been writing about method, diagnostic and investigative, for over 25 years, and was happy to accept the suggestion of Seymour Weingar ten, of Plenum Press, that I publish a collection of these papers. What has ended up as two volumes was originally conceived as one, for I feel that there is more similarity of method in assessment, prediction, and research than appears on the surface. The General Introduction and Chapter 1 of Volume 1 state the point of view of the entire work. 364 pp. Englisch.