springer us jul 2012 (326 risultati)

Taschenbuch. Condizione: Neu. Neuware -Every amateur astronomer - and many non-astronomers - will be familiar with seeing a 'star' that shows thatcharacteristic steady slide across the starry background of the sky. Artificial satellites can be seen any night, and some as bright as the planets. But how many of us can identify which satellites or spent launch vehicle casing we are seeing Artificial Satellites and How to Observe Them describes all the different satellites that can be observed without optical aid, including of course the International Space Station and the many spy satellites operated by different nations. Richard Schmude looks at them in detail and describes how they can be observed by amateurs, how to recognize them, and even how to predict their orbits.Artificial satellites have changed since the beginning of the millenium. Several additional countries have launched them. And amateur astronomers have utilized digital cameras in order to image satellites to a resolution of about three feet. This book describes how to recognize, observe, and image satellites. Examples of recent images and how they were made are given. It also offers up-to-date descriptions of the many satellites that are orbiting the Earth and other celestial bodies. Readers can learn how satellites impact our day-to-day lives. In short, Artificial Satellites and How to Observe Them is a detailed and up-to-date overview of artificial satellites and how to study them in the night sky.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -¿¿ ¿Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus onprotein-protein interaction predictions in bacteria. The authors willdescribe these methods and further highlight its use to predict various biological pathways andcomplexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 72 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Multifractal Financial Markets ¿explores appropriate models for estimating risk and profiting from market swings, allowing readers to develop enhanced portfolio management skills and strategies. Fractals in finance allow us to understand market instability and persistence. When applied to financial markets, these models produce the requisite amount of data necessary for gauging market risk in order to mitigate loss. This brief delves deep into the multifractal market approach to portfolio management through real-world examples and case studies, providing readers with the tools they need to forecast profound shifts in market activity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 148 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -'How to Observe the Sun Safely, 2nd Edition' gives all the basic information and advice the amateur astronomer needs to get started in observing our own ever-fascinating star. Unlike many other astronomical objects, you do not need a large telescope or expensive equipment to observe the Sun. And it is possible to take excellent pictures of the Sun with today's low-cost digital cameras!This title concentrates on providing practical, on-the-spot advice to the amateur astronomer who is interested in observing the Sun, using commercially available equipment. This book surveys what is visible on the Sun, before describing how to record solar features and measure solar activity levels. There is also an account of how to use H-alpha and Calcium-K filters to observe and record prominences and other features of the solar chromosphere, the Sun's inner atmosphere. Because we are just entering a period of high activity on the Sun, following a long, quiet period, many more amateur astronomers will become interested in observing it.The second edition includes an update of Chapter 2 to reflect advances in solar observing equipment since 2002, and a section on building a solar projection box, originally included in the main body of this chapter has been moved to Appendix A. Also Chapter 6 thru 8 have been completely revised to give amateur astronomers advice on how to use film to photograph the Sun, and how to use digital cameras. This new edition also includes more than twice as many illustrations as the first and almost half of them new images.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condizione: Neu. Neuware -This work presents lines of investigation and scientific achievements of the Ukrainian school of optimization theory and adjacent disciplines. These include the development ofapproaches to mathematical theories, methodologies, methods, and application systems for the solution of applied problems in economy, finances, energy saving, agriculture, biology, genetics, environmental protection, hardware and software engineering, information protection, decision making, pattern recognition, self-adapting control of complicated objects, personnel training, etc. The methods developed include sequential analysis of variants, nondifferential optimization, stochastic optimization, discrete optimization, mathematical modeling, econometric modeling, solution of extremum problems on graphs, construction of discrete images and combinatorial recognition, etc. Some of these methods became well known in the world's mathematical community and are now known as classic methods.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Although the history of photomedicine dates back thousands of years, with even preliterate cultures appreciating the healing properties of sunlight, for many workers in the discipline photomedicine is associated with the observation about 100 years ago of Niels Finsen, a Danish physician. Finsen recognized that people with tuberculosis who lived in Norway and who had very little exposure to sunlight often developed facial lesions (lupus vulgaris) which would decrease and sometimes disappear during the summer months. This very observant physician reasoned that artificial light ought to produce the same effect as sunlight and began utilizing the radiation from the newly available carbon arc. At first, he used a glass lens to concentrate the radiation, but since this produced considerable burning, he replaced this with a hollow glass lens filled with water. However, while this reduced the heat burns, it did not actually duplicate the effect of direct sunlight. Finally, using a hollow lens filled with water but equipped with quartz windows, Finsen was able to imitate, even improve upon, the effect of sunlight. As a result, lupus vulgaris was practically eliminated from the Scandinavian countries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 688 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This volume provides an important new synthesis of archaeological work carried out in Australia on the post-contact period. It draws on dozens of case studies from a wide geographical and temporal span to explore the daily life of Australians in settings such as convict stations, goldfields, whalers' camps, farms, pastoral estates and urban neighbourhoods. The different conditions experienced by various groups of people are described in detail, including rich and poor, convicts and their superiors, Aboriginal people, women, children, and migrant groups. The social themes of gender, class, ethnicity, status and identity inform every chapter, demonstrating that these are vital parts of human experience, and cannot be separated from archaeologies of industry, urbanization and culture contact.The book engages with a wide range of contemporary discussions and debates within Australian history and the international discipline of historical archaeology. The colonization of Australia was part of the international expansion of European hegemony in the eighteenth and nineteenth century. The material discussed here is thus fundamentally part of the global processes of colonization and the creation of settler societies, the industrial revolution, the development of mass consumer culture, and the emergence of national identities. Drawing out these themes and integrating them with the analysis of archaeological materials highlights the vital relevance of archaeology in modern society.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 444 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Apollo was known for its engineering triumphs, but its success also came from a disciplined management style. This excellent account of one of the most important personalities in early American human spaceflight history describes for the first time how George E. Mueller, the system manager of the human spaceflight program of the 1960s, applied the SPO methodology and other special considerations such as ¿all-up¿testing, resulting in the success of the Apollo Program. Wernher von Braun and others did not readily accept such testing or Mueller¿s approach to system management, but later acknowledged that without them NASA would not have landed astronauts on the Moon by 1969. While Apollo remained Mueller¿s priority, from his earliest days at the agency, he promoted a robust post-Apollo Program which resulted in Skylab, the Space Shuttle and the International Space Station. As a result of these efforts, Mueller earned the sobriquet: ¿the father of the space shuttle.¿ Following his success at NASA, Mueller returned to industry. Although he did not play a leading role in human spaceflight again, in 2011 the National Air and Space Museum awarded him their lifetime achievement trophy for his contributions.Following the contributions of George E. Mueller, in this unique book Arthur L. Slotkin answers such questions as: exactly how did the methods developed for use in the Air Force ballistic missile programs get modified and used in the Apollo Program How did George E. Mueller, with the help of others, manage the Apollo Program How did NASA centers, coming from federal agencies with cultures of their own, adapt to the new structured approach imposed from Washington George E. Mueller is the ideal central character for this book. He was instrumental in the creation of Apollo extension systems leading to Apollo, the Shuttle, and today¿s ISS and thus was a pivotal figure in early American human spaceflight history.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The aim of this book is to explain the basic concepts and phenomena of quantum mechanics by means of visualisation. Computer-generated illustrations in color are used extensively throughout the text, helping to establish the relation between quantum mechanics¿wave functions, interference, atomic structure, and so forth¿and classical physics¿point mechanics, statistical mechanics, and wave optics. Even more important, by studying the pictures in parallel with the text, readers develop an intuition for such notoriously abstract phenomena as:the tunnel effectexcitation and decay of metastable stateswave-packet motion within a wellsystems of distinguishable and indistinguishable particlesfree wave packets and scattering in 3 dimensionsangular-momentum decompositionstationary bound states in various 3-dimensional potentialshybrid statesKepler motion of wave packets in the Coulomb fieldspin and magnetic resonanceIllustrations from experiments in a variety of fields, including chemistry, and molecular, atomic, nuclear, and particle physics, underline the basic as well as the practical importance of quantum mechanics. In the present, fourth edition all computer graphics are presented in full colour. It also contains additional physics topics such as hybridisation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 496 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This book consists of three parts, rather different in level and purpose: The first part was originally written for quantum chemists. It describes the correspondence, due to Frobenius, between linear representations and charac ters. This is a fundamental result, of constant use in mathematics as well as in quantum chemistry or physics. I have tried to give proofs as elementary as possible, using only the definition of a group and the rudiments of linear algebra. The examples (Chapter 5) have been chosen from those useful to chemists. The second part is a course given in 1966 to second-year students of I'Ecoie Normale. It completes the first on the following points: (a) degrees of representations and integrality properties of characters (Chapter 6); (b) induced representations, theorems of Artin and Brauer, and applications (Chapters 7-11); (c) rationality questions (Chapters 12 and 13). The methods used are those of linear algebra (in a wider sense than in the first part): group algebras, modules, noncommutative tensor products, semisimple algebras. The third part is an introduction to Brauer theory: passage from characteristic 0 to characteristic p (and conversely). I have freely used the language of abelian categories (projective modules, Grothendieck groups), which is well suited to this sort of question. The principal results are: (a) The fact that the decomposition homomorphism is surjective: all irreducible representations in characteristic p can be lifted 'virtually' (i.e., in a suitable Grothendieck group) to characteristic O.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -With the first edition out of print, we decided to arrange for republi cation of Denumerrible Markov Ohains with additional bibliographic material. The new edition contains a section Additional Notes that indicates some of the developments in Markov chain theory over the last ten years. As in the first edition and for the same reasons, we have resisted the temptation to follow the theory in directions that deal with uncountable state spaces or continuous time. A section entitled Additional References complements the Additional Notes. J. W. Pitman pointed out an error in Theorem 9-53 of the first edition, which we have corrected. More detail about the correction appears in the Additional Notes. Aside from this change, we have left intact the text of the first eleven chapters. The second edition contains a twelfth chapter, written by David Griffeath, on Markov random fields. We are grateful to Ted Cox for his help in preparing this material. Notes for the chapter appear in the section Additional Notes. J.G.K., J.L.S., A.W.K.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 500 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Completely revised and up-to-date, this wide-ranging, comprehensive treatise examines the many different aspects of vegetables from an international perspective. The diversity and depth of coverage of vegetables is largely due to the extensive background and experiences of the authors, Vincent Rubatzky and Mas Yamaguchi, as well as considerable input from colleagues and expert reviewers.This logically-organized text, filled with numerous illustrations, photographs, and tables, begins with an easy-to-read introduction to such topics as: the current role of vegetables as a world food crop, the origin and classification of vegetables, vegetables in human nutrition, and plant toxicants and folklore concerning vegetables. Background material on the basic principles for growing crops and production under adverse conditions are also featured in this section. Much of the material covered in the book focuses on the major and minor vegetables, their origin, taxonomy, botany, physiology, production and post harvest handling, and composition and use. In addition, current world production statistics are provided for many vegetable crops as well as listings of important diseases, insects, and other pests for many family groups.New features of this edition include: \*Three new chapters covering mushrooms, aquatic vegetables, and herbs and spices \*several appendix tables listing vegetables according to family, genus, species, nutritive value, and recommended storage conditions for many vegetables The introductory chapter offers an excellent background of the role of vegetables for the beginning and advanced students, both in the U.S. and worldwide. The chapters following provide extension professionals, professors, agricultural agencies, commercial growers, and processing and seed industry personnel with a better understanding of individual vegetable species.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 896 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -¿Whatareimportantprognosticfactors ¿Answerstosuchquestionsprovidethe basisforbetterpreventionandtreatmentofdiseases. Many people contributed to the writing of this book: medical students in Denmark,studentsofepidemiologyattheIEAEEPEsummercourseinFlorence, Italy,andstudentsofpublichealthinLosAngeles. Withouttechnicalassistance v vi Preface fromGitteNielsen,JenadeShelley,NinaHoheandPamMasangkaythebookwould neverhavematerialized. LosAngeles,California JørnOlsen Odense,Denmark KaareChristensen IowaCity,Iowa JeffMurray Stockholm,Sweden AndersEkbom Contents Part I Descriptive Epidemiology 1 Measures of Disease Occurrence . . . . . . . . . . . . . . . . . . . 3 IncidenceandPrevalence . . . . . . . . . . . . . . . . . . . . . . . . 4 Incidence. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 RatesandDynamicPopulations . . . . . . . . . . . . . . . . . . . . . 7 CalculatingObservationTime. . . . . . . . . . . . . . . . . . . . . . 9 Prevalence,Incidence,Duration . . . . . . . . . . . . . . . . . . . . . 10 MortalityandLifeExpectancy . . . . . . . . . . . . . . . . . . . . . 11 LifeExpectancy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 2 Estimates of Associations . . . . . . . . . . . . . . . . . . . . . . . 15 3 Age Standardization. . . . . . . . . . . . . . . . . . . . . . . . . . 19 4 Causes of Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 5 Descriptive Epidemiology in Public Health. . . . . . . . . . . . . . 29 GraphicalModelsofCausalLinks . . . . . . . . . . . . . . . . . . . 33 References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 6 Descriptive Epidemiology in Genetic Epidemiology. . . . . . . . . 37 OccurrenceDatainGeneticEpidemiology . . . . . . . . . . . . . . . 37 ClusteringofTraitsandDiseasesinFamilies . . . . . . . . . . . . . .Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 176 pp. Englisch.

Buch. Condizione: Neu. Neuware -Investment and risk management problems are fundamental problems for financial institutions and involve both speculative and hedging decisions. A structured approach to these problems naturally leads one to the field of applied mathematics in order to translate subjective probability beliefs and attitudes towards risk and reward into actual decisions.In Risk and Portfolio Analysis the authors present sound principles and useful methods for making investment and risk management decisions in the presence of hedgeable and non-hedgeable risks using the simplest possible principles, methods, and models that still capture the essential features of the real-world problems. They use rigorous, yet elementary mathematics, avoiding technically advanced approaches which have no clear methodological purpose and are practically irrelevant. The material progresses systematically and topics such as the pricing and hedging of derivative contracts, investment and hedging principles from portfolio theory, and risk measurement and multivariate models from risk management are covered appropriately. The theory is combined with numerous real-world examples that illustrate how the principles, methods, and models can be combined to approach concrete problems and to draw useful conclusions. Exercises are included at the end of the chapters to help reinforce the text and provide insight.This book will serve advanced undergraduate and graduate students, and practitioners in insurance, finance as well as regulators. Prerequisites include undergraduate level courses in linear algebra, analysis, statistics and probability.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 352 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -From the Introduction: 'We shall base our discussion on a set-theoretical foundation like that used in developing analysis, or algebra, or topology. We may consider our task as that of giving a mathematical analysis of the basic concepts of logic and mathematics themselves. Thus we treat mathematical and logical practice as given empirical data and attempt to develop a purely mathematical theory of logic abstracted from these data.' There are 31 chapters in 5 parts and approximately 320 exercises marked by difficulty and whether or not they are necessary for further work in the book.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 544 pp. Englisch.

Buch. Condizione: Neu. Neuware -Given the widespread use of real-time multitasking systems, there are tremendous optimization opportunities if reconfigurable computing can be effectively incorporated while maintaining performance and other design constraints of typical applications. The focus of this book is to describe the dynamic reconfiguration techniques that can be safely used in real-time systems. This book provides comprehensive approaches by considering synergistic effects of computation, communication as well as storage together to significantly improve overall performance, power, energy and temperature.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book provides anyone needing a primer on random signals and processes with a highly accessible introduction to these topics. It assumes a minimal amount of mathematical background and focuses on concepts, related terms and interesting applications to a variety of fields. All of this is motivated by numerous examples implemented with MATLAB, as well as a variety of exercises at the end of each chapter.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 548 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book features various, ultra low energy, variability resilient SRAM circuit design techniques for wireless sensor network applications. Conventional SRAM design targets area efficiency and high performance at the increased cost of energy consumption, making it unsuitable for computation-intensive sensor node applications. This book, therefore, guides the reader through different techniques at the circuit level for reducing energy consumption and increasing the variability resilience. It includes a detailed review of the most efficient circuit design techniques and trade-offs, introduces new memory architecture techniques, sense amplifier circuits and voltage optimization methods for reducing the impact of variability for the advanced technology nodes.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Buch. Condizione: Neu. Neuware -This book provides readers specializing in ultra-low power supply design for self-powered applications an invaluable reference on reconfigurable switched capacitor power converters. Readers will benefit from a comprehensive introduction to the design of robust power supplies for energy harvesting and self-power applications, focusing on the use of reconfigurable switched capacitor based DC-DC converters, which is ideal for such applications. Coverage includes all aspects of switched capacitor power supply designs, from fundamentals, to reconfigurable power stages, and sophisticated controller designs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 188 pp. Englisch.

Buch. Condizione: Neu. Neuware -Clinical pharmacology plays an important role in today¿s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography ¿ mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 484 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated a meeting by a small group of toxicologists at the University of Turku, in Finland, in 1975 (Jollow et al. , 1977). The growing interest in this field of research led to subsequent symposia at the University of Surrey, in England in 1980 (Snyder et al. , 1982), and the University of Maryland in the U. S. A. in 1985 (Kocsis et al. , 1986). The Fourth International Symposium on Biological Reactive Intermediates was hosted by the Center for Toxicology at the University of Arizona and convened in Tucson, Arizona, January 14-17, 1990. Over 300 people attended. There were 60 platform presentations by invited speakers, and 96 volunteer communications in the form of posters were offered. These meetings have grown from a small group of scientists working in closely related areas to a major international series of symposia which convene every five years to review, and place in context, the latest advances in our understanding of the formation, fate and consequences of biological reactive intermediates. The Organizing Committee: Allan H. Conney, Robert Snyder (Co-chairman), and Charlotte M. Witmer (Rutgers University, Piscataway, NJ), David J. Jollow Co chairman) (Medical University, South Carolina, Charleston, SC), 1. Glenn Sipes (Co chairman) (University of Arizona, Tucson, AZ), James J. Kocsis and George F.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 916 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This volume represents a portion of the Proceedings of the Sixth International Meeting of the Reticuloendothelial Society. There is little question that the University of Freiburg was a most appropriate choice as the site of the meeting since, in essence, the Society was founded here when Aschoff undertook his classical studies on the macrophage and discovered what may well have been the last remaining biological system. In the approximate fifty years which have elapsed since Aschoff introduced the descriptive term Reticuloendothelial System to unify those cells with the common property of phagocytosis, one finds investigative activity at the highest level in all areas of reticuloendothelial involvement. Indeed, the topics covered in the present volume would of necessity require that the common property of phagocytosis which led to the formulation of the reticuloendothelial system be modified. The common basis at the present is clearly no longer phagocytic expression, but the unifying basis of host defense. The totality of reticuloendothelial involvement in host-defense is clearly reflected by the diverse scientific backgrounds and research interests of the participants of the meeting. Remarkable advances in appreciating the involvement of the RES in maintaining the well-being of the host against a variety of endogenous and exogenous factors have been made since volume I of the Advances in Experimental Biology and Medicine on the reticulo endothelial system was published.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 460 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -These Proceedings are the outcome of the First Tarbox Parkinson's Disease Symposium held October 14-16, 1976, at the South Park Inn in Lubbock, Texas. The Symposium was sponsored by the Department of Pharmacology and Therapeutics and the Tarbox Parkinson's Disease In stitute of the Texas Tech University School of Medicine at Lubbock. The Tarbox Parkinson's Disease Institute was established in 1973 with funds appropriated by the State of Texas and is dedicated to re search, patient care, and educational activities related to Parkinson's disease. The Institute is named after Mr. Elmer L. Tarbox, who recently served the Lubbock area as a Representative to the Texas Legislature, and is himself a parkinsonian patient. Mr. and Mrs. Tarbox attended the Symposium as honored guests. The First Tarbox Parkinson's Disease Symposium was devoted to both basic and clinical aspects of Parkinson's disease, with an emphasis on discussion of drug therapy. This discussion focused not only on readily available drugs such as levodopa, but also on new investigational drugs such as bromocriptine. Thanks are especially due to Thelma Saunders and the office staff of the Department of Pharmacology and Therapeutics, Texas Tech Univer sity School of Medicine, for their excellent service in producing camera-ready copy for the Publisher. Thanks are also due to Fathy S. Messiha, Program Chairman, to the other committee members, and to the staff of the Office of Continuing Education and Faculty Development. The Symposium could not have succeeded without their help.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Conference was published by Plenum Press in 1986 as Volume 29 in Advances in Behavioral Biology, under the title 'Alzheimer's and Parkinson's Diseases: Strategies for Research and Development.' We are happy that the comprehensive texts of the oral and poster presentations of the Second Conference could again be published within the framework of this series. Since the First Conference in 1985, rapid progress has been made in both basic and 'therapeutic aspects of these diseases. About 700 scientists from allover the world participated in the Second Conference, and 300 papers were presented in oral and poster sessions. Many people and organizations have helped to organize this multi disciplinary international conference and hence have contributed to the scientific quality of these two volumes. We thank the members of the organizing committee, the organizations that provided financial support, and the contributing scientists for their enthusiastic participation. These two volumes follow the same publishing philosophy as the volume derived from the First Conference. They span a broad spectrum of topics and bridge preclinical and clinical concepts related to these diseases.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 836 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -It is 5 years since the publication of the seminal paper on ¿Design Science in Information Systems Research¿ by Hevner, March, Park, and Ram in MIS Quarterly and the initiation of the Information Technology and Systems department of the Communications of AIS. These events in 2004 are markers in the move of design science to the forefront of information systems research. A suf cient interval has elapsed since then to allow assessment of from where the eld has come and where it should go. Design science research and behavioral science research started as dual tracks when IS was a young eld. By the 1990s, the in ux of behavioral scientists started to dominate the number of design scientists and the eld moved in that direction. By the early 2000s, design people were having dif culty publishing in mainline IS journals and in being tenured in many universities. Yes, an annual Workshop on Information Technology and Systems (WITS) was established in 1991 in conju- tion with the International Conference on Information Systems (ICIS) and grew each year. But that was the extent of design science recognition. Fortunately, a revival is underway. By 2009, when this foreword was written, the fourth DESRIST c- ference has been held and plans are afoot for the 2010 meeting. Design scientists regained respect and recognition in many venues where they previously had little.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The research studies reported in this book were completed between June, 1976 and November, 1979, with a USPHS research grant (MH- 27849) from the Center for Studies of Crime and Delinquency, National Institute of Mental Health. Every phase of the project was an exercise in combining the research methods of psychology with the concerns of law, legal systems, and legal process. Research psychologists will be especially interested in our efforts to apply psychological constructs and research methods to a difficult decision-making problem in law. This report describes in some detail the project's development of experimental measures of psychological condi tions related to legal standards and demonstrates the ways in which research design was influenced by concerns of law and the juvenile justice system. Lawyers, judges, and youth advocate groups have already ex pressed considerable interest in the implications of the project's results for the formation and modification of juvenile law and procedure. In each chapter, I have attempted to describe carefully the ways in which the empirical research results are applicable to these concerns, and I have tried to specify the limits which must be acknowledged in inter preting the results for application in the legal process.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.

Buch. Condizione: Neu. Neuware -Microdroplet technology has recently emerged to provide new and diverse applications via microfluidic functionality, especially in various areas of biology and chemistry. This book, then, gives an overview of the principle components and wide-ranging applications for state-of-the-art of droplet-basedmicrofluidics. Chapter authors are internationally-leading researchers from chemistry, biology, physics and engineering that present various key aspects of micrdroplet technology -- fundamental flow physics, methodology and components for flow control, applications in biology and chemistry, and a discussion of future perspectives. This book acts as a reference for academics, post-graduate students, and researcher wishing to deepen their understand of microfluidics and introduce optimal design and operation of new droplet-based microfluidic devices for more comprehensive analyte assessments.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 256 pp. Englisch.

Buch. Condizione: Neu. Neuware -The revised and extended papers collected in this volume represent the cutting-edge of research at the nexus of electrical engineering and intelligent systems. They were selected from well over 1000 papers submitted to the high-profile international World Congress on Engineering held in London in July 2011. The chapters cover material across the full spectrum of work in the field, including computational intelligence, control engineering, network management, and wireless networks. Readers will also find substantive papers on signal processing, Internet computing, high performance computing, and industrial applications.The Electrical Engineering and Intelligent Systems conference, as part of the 2011 World Congress on Engineering was organized under the auspices of the non-profit International Association of Engineers (IAENG). With more than 30 nations represented on the conference committees alone, the Congress features the best and brightest scientific minds from a multitude of disciplines related to engineering. These peer-reviewed papers demonstrate the huge strides currently being taken in this rapidly developing field and reflect the excitement of those at the frontiers of this research.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 436 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Naturally occurring antinutrients and food toxicants, and those formed during food processing, adversely affect the nutri tional quality and safety of foods. Because of the need to improve food quality and safety by plant breeding, fortification with appropriate nutrients, and processing methods, and because of the growing concern about possible direct relationships between diet and diseases, research is needed to: (1) evaluate the nutritive quality and safety of crops and fortified, supplemented, and processed foods; (2) define conditions that favor or minimize the formation of nutritionally antagonistic and toxic compounds in foods; and (3) define the toxicology, metabolism, and mechanisms of the action of food ingredients and their metabolites. As scientists interested in improving the safety of the food supply, we are challenged to respond to the general need for exploring: (1) possible adverse consequences of antinutrients and food toxicants; and (2) factors which contribute to the formation and inactivation of undesirable compounds in foods. Medical research offers an excellent analogy. Studies on causes and mechanisms of disease processes are nearly always accompanied by parallel studies on preventive measures and cures. Such an approach offers the greatest possible benefits to the public.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 600 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -The Fifth International Symposium on Human Purine and Pyrimidine Metabolism was held in San Diego, California (U. S. A. ) in July and August of 1985. Previous meetings in this series were held in Tel Aviv (Israel), Baden (Austria), Madrid (Spain) and Maastricht (The Netherlands). The proceedings of each of these meetings were published by Plenum. The next meeting will be in Japan. This Symposium differed from those that went before in that it per mitted us to honor Dr. J. E. Seegmiller, Professor of Medicine at the University of California San Diego, for his many contributions to our understanding of purine metabolism in man. This publication is dedicated as a Festschrift to Jay. Dr. Richard W. E. Watts delivered the keynote address outlining in scholarly fashion the history of Dr. Seegmiller's accomplishments in research on purine metabolism and the great number of currently active scientists in this field who have worked with him. This address is published as the first contribution to Volume I. Dr. Dewitt Stetten, Jr. , was scheduled to be the speaker at our banquet. Unfortunate ly, he could not be with us. Dr. Seegmiller has written an appreciation of Dr. Stetten and his contributions to our field, and this has been pub lished following Dr. Watts' paper. The growth of knowledge in purine and pyrimidine metabolism continues to be exponential. The variety of subjects included in these volumes is impressive.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 640 pp. Englisch.