springer us mai 1994 (19 risultati)

Buch. Condizione: Neu. Neuware - More often than not, progress in medicine occurs incrementally. The report of an 'important' new observation is typically greeted by a mixture of excitement and skepticism. Yet the true value of the discovery may not be known for several years until it is confirmed (or refuted) by independently conducted studies. In some cases, controversy may continue to shroud a topic due to the discordant results generated by different research groups. Since the last Gynecologic Oncology volume in the Cancer Treatment and Research series, a number of new areas have emerged that shed new light on the pathogenesis, diagnosis, and treatment of gynecologic malignancies. In this volume of the Cancer Treatment and Research series, I have attempted to integrate articles that highlight some of these newest developments with chapters that provide an overview of selected areas of controversy. This volume is not meant to be an abbreviated text of gynecologic oncology but rather a collection of selected works that can provide the reader with a better perspective on the areas of change within the field. The application of molecular biology to cervical cancer has allowed us to understand more completely the roles of human papilloma viruses and cellular oncogenes in the development of cancer of the uterine cervix.

Buch. Condizione: Neu. Neuware - As we approach the end of the present century, the elementary particles of light (photons) are seen to be competing increasingly with the elementary particles of charge (electrons/holes) in the task of transmitting and processing the insatiable amounts of infonnation needed by society. The massive enhancements in electronic signal processing that have taken place since the discovery of the transistor, elegantly demonstrate how we have learned to make use of the strong interactions that exist between assemblages of electrons and holes, disposed in suitably designed geometries, and replicated on an increasingly fine scale. On the other hand, photons interact extremely weakly amongst themselves and all-photonic active circuit elements, where photons control photons, are presently very difficult to realise, particularly in small volumes. Fortunately rapid developments in the design and understanding of semiconductor injection lasers coupled with newly recognized quantum phenomena, that arise when device dimensions become comparable with electronic wavelengths, have clearly demonstrated how efficient and fast the interaction between electrons and photons can be. This latter situation has therefore provided a strong incentive to devise and study monolithic integrated circuits which involve both electrons and photons in their operation. As chapter I notes, it is barely fifteen years ago since the first demonstration of simple optoelectronic integrated circuits were realised using m-V compound semiconductors; these combined either a laser/driver or photodetector/preamplifier combination.

Buch. Condizione: Neu. Neuware - When one deals with cancer, the hepatobiliary malignancies present a chal lenge to the oncologists that can be characterized as a series of unsolved clinical and biological dilemmas. Liver metastases from colorectal and other gastrointestinal malignancies, hepatocellular carcinoma, cholangiocar cinoma, and gall bladder cancer present an array of problems but have two features in common. These are high morbidity and mortality with an overall poor result from treatment. Why is it that hepatobiliary cancer carries with it such a dismal prognosis First of all, these diseases present, for the most part, in an advanced state. To this point in time the oncologist has had no help from early diagnosis or screening. Only the occasional patient followed by ultrasound or a tumor marker has the disease diagnosed in an asymptomatic state. By the time these diseases become symptomatic, curative treatment options have usually disappeared. Evolution has placed the liver in a protected position in order to avoid injury to the soft parenchyma. As with many other internal organs, the nerve supply is extremely limited. These two anatomic features result in a great lack of early warning signs of cancer.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is the culmination of a research program conducted in Colombia during the past several years. The fundamental aim of the program was to develop neuropsychological tests for Spanish speakers, especially elderly individuals and those with limited edu cational attainment. The lack of norms for these populations repre sents a significant practical problem not only in developing countries but also in more developed countries. For example, norms are usually obtained with middle-class Anglo-Saxon English-speaking popula tions, often university students, and such norms do not usually include individuals older than 65 years. Furthermore, very few neuro psychological tests have been developed for Spanish speakers; fre quently, tests are translated into Spanish (often poor translations at that), but the norms used are still those obtained from English speaking populations. This volume summarizes the normative results of this research program. We anticipate that these tests and norms will be particularly useful in the neuropsychological evaluation of Spanish speakers, especially those with limited educational attainment, and the elderly. The United States represents the fifth largest Spanish-speaking coun try in the world (after Mexico, Spain, Argentina, and Colombia), with over 20 million speakers. It is anticipated that by the year 2025 there will be as many Hispanics in the United States as members of all other ethnic minority groups combined. Further, about 10% of the U. S. population are considered functionally illiterate, with Hispanics rep resenting an unusually large segment. 228 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present volume presents six chapters, two of them fairly brief, covering both fundamental and applied electrochemistry. The latter aspect has, of course, historical significance in the subject as well as a major technological profile in recent decades, while intimate connections between these complementary facets of the subject have always been a driving force for its earlier and continu ing development. In the Modern Aspects of Electrochemistry series we have periodically included contributions from the several schools of Russi~n electrochemistry. This approach is continued in the present volume by inclusion of the chapter by Benderskii, Brodskii, Daikhin, and Velichko from the Frumkin Institute, Moscow, on phase transitions among molecules adsorbed in the double-layer interphase at electrodes. This topic has attracted attention for some years through the works of the Russian school and of Gierst and Buess-Herman. Such behavior is also related to the important phenomenon of self-assembly of molecules in films at interfaces. In Chapter 1, these authors give an account of the factors associated with two-dimensional phase transitions and associated orientation effects with polar adsorbates at electrode interfaces. The theoretical interpretation of these effects are also treated in some detail. Chapter 2, by Rusling, deals with electrochemistry and electro catalysis in microemulsions, thus connecting aspects of electrode kinetics, adsorption at electrode interfaces, and colloid chemistry. 364 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In brief summary, the following results were presented in this work: - A linear time approach was developed to find register requirements for any specified CS schedule or filled MRT. - An algorithm was developed for finding register requirements for any kernel that has a dependence graph that is acyclic and has no data reuse on machines with depth independent instruction templates. - We presented an efficient method of estimating register requirements as a function of pipeline depth. - We developed a technique for efficiently finding bounds on register require ments as a function of pipeline depth. - Presented experimental data to verify these new techniques. - discussed some interesting design points for register file size on a number of different architectures. REFERENCES [1] Robert P. Colwell, Robert P. Nix, John J O'Donnell, David B Papworth, and Paul K. Rodman. A VLIW Architecture for a Trace Scheduling Com piler. In Architectural Support for Programming Languages and Operating Systems, pages 180-192, 1982. [2] C. Eisenbeis, W. Jalby, and A. Lichnewsky. Compile-Time Optimization of Memory and Register Usage on the Cray-2. In Proceedings of the Second Workshop on Languages and Compilers, Urbana l/inois, August 1989. [3] C. Eisenbeis, William Jalby, and Alain Lichnewsky. Squeezing More CPU Performance Out of a Cray-2 by Vector Block Scheduling. In Proceedings of Supercomputing '88, pages 237-246, 1988. [4] Michael J. Flynn. Very High-Speed Computing Systems. Proceedings of the IEEE, 54:1901-1909, December 1966. 300 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book is the culmination of a research program conducted in Colombia during the past several years. The fundamental aim of the program was to develop neuropsychological tests for Spanish speakers, especially elderly individuals and those with limited edu cational attainment. The lack of norms for these populations repre sents a significant practical problem not only in developing countries but also in more developed countries. For example, norms are usually obtained with middle-class Anglo-Saxon English-speaking popula tions, often university students, and such norms do not usually include individuals older than 65 years. Furthermore, very few neuro psychological tests have been developed for Spanish speakers; fre quently, tests are translated into Spanish (often poor translations at that), but the norms used are still those obtained from English speaking populations. This volume summarizes the normative results of this research program. We anticipate that these tests and norms will be particularly useful in the neuropsychological evaluation of Spanish speakers, especially those with limited educational attainment, and the elderly. The United States represents the fifth largest Spanish-speaking coun try in the world (after Mexico, Spain, Argentina, and Colombia), with over 20 million speakers. It is anticipated that by the year 2025 there will be as many Hispanics in the United States as members of all other ethnic minority groups combined. Further, about 10% of the U. S. population are considered functionally illiterate, with Hispanics rep resenting an unusually large segment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 228 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In brief summary, the following results were presented in this work: ¿ A linear time approach was developed to find register requirements for any specified CS schedule or filled MRT. ¿ An algorithm was developed for finding register requirements for any kernel that has a dependence graph that is acyclic and has no data reuse on machines with depth independent instruction templates. ¿ We presented an efficient method of estimating register requirements as a function of pipeline depth. ¿ We developed a technique for efficiently finding bounds on register require ments as a function of pipeline depth. ¿ Presented experimental data to verify these new techniques. ¿ discussed some interesting design points for register file size on a number of different architectures. REFERENCES [1] Robert P. Colwell, Robert P. Nix, John J O'Donnell, David B Papworth, and Paul K. Rodman. A VLIW Architecture for a Trace Scheduling Com piler. In Architectural Support for Programming Languages and Operating Systems, pages 180-192, 1982. [2] C. Eisenbeis, W. Jalby, and A. Lichnewsky. Compile-Time Optimization of Memory and Register Usage on the Cray-2. In Proceedings of the Second Workshop on Languages and Compilers, Urbana l/inois, August 1989. [3] C. Eisenbeis, William Jalby, and Alain Lichnewsky. Squeezing More CPU Performance Out of a Cray-2 by Vector Block Scheduling. In Proceedings of Supercomputing '88, pages 237-246, 1988. [4] Michael J. Flynn. Very High-Speed Computing Systems. Proceedings of the IEEE, 54:1901-1909, December 1966.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 300 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nearly half of the known species of mammals alive today (more than 1600) are rodents or 'gnawing mammals' (Nowak and Paradiso, 1983). The diversity of rodents is greater than that of any other order of mammals. Thus, it is not surprising that the fossil record of this order is extensive and fossil material of rodents from the Tertiary is known from all continents except Antarctica and Australia. The purpose of this book is to compile the published knowledge on fossil rodents from North America and present it in a way that is accessible to paleontologists and mammalogists interested in evolutionary studies of ro dents. The literature on fossil rodents is widely scattered between journals on paleontology and mammalogy and in-house publications of museums and universities. Currently, there is no single source that offers ready access to the literature on a specific family of rodents and its fossil history. This work is presented as a reference text that can be useful to specialists in rodents (fossil or recent) as weIl as mammalian paleontologists working on whole faunas. Because the diversity of rodents in the world is essentially limitless, any monograph that included all fossil rodents would similarly be limitless. Hence, this book is limited to the re cord of Tertiary rodents of North America. The several species of South American (caviomorph) rodents that invaded North America near the end of the Tertiary are also not included in this text. 340 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The world is getting warmer. Among scientists concerned with global climate change this is the broad consensus. How fast and by how much, are questions which cannot be answered quantitatively, but the probability of rising temperatures must be faced in a prudent manner - there is enough certainty of change so that we must anticipate and prepare before irreparable damage is done to our world. Even if it isn't going to be as bad as some people think, the actions we propose will benefit the earth and give us a kind of insurance. The root of the change is population growth, and its attendant demand for energy. While the developed world expects to hold future emissions relatively steady, the developing countries, where population growth is most rampant, will expand the use of energy as they aspire to a better quality of life. H greater energy use is inevitable it behooves us to produce that energy in the least objectionable manner, and to produce it where the cost is lowest in dollars, GNP, and environmental change. 236 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The American Institute for Cancer Research (AICR) sponsored its third annual confer ence on nutrition and cancer. The theme was 'Diet and Cancer: Markers, Prevention, and Treatment. ' The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The world is getting warmer. Among scientists concerned with global climate change this is the broad consensus. How fast and by how much, are questions which cannot be answered quantitatively, but the probability of rising temperatures must be faced in a prudent manner - there is enough certainty of change so that we must anticipate and prepare before irreparable damage is done to our world. Even if it isn't going to be as bad as some people think, the actions we propose will benefit the earth and give us a kind of insurance. The root of the change is population growth, and its attendant demand for energy. While the developed world expects to hold future emissions relatively steady, the developing countries, where population growth is most rampant, will expand the use of energy as they aspire to a better quality of life. H greater energy use is inevitable it behooves us to produce that energy in the least objectionable manner, and to produce it where the cost is lowest in dollars, GNP, and environmental change.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume analyzes both the theoretical and experimental aspects of neutron spectroscopy of solids, whereby complex crystals may be analyzed in relation to the theories of symmetry and neutron scattering near a structural or magnetic transition. 396 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The American Institute for Cancer Research (AICR) sponsored its third annual confer ence on nutrition and cancer. The theme was 'Diet and Cancer: Markers, Prevention, and Treatment. ' The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation. 288 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume analyzes both the theoretical and experimental aspects of neutron spectroscopy of solids, whereby complex crystals may be analyzed in relation to the theories of symmetry and neutron scattering near a structural or magnetic transition.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 392 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This timely resource guides novices and experts through the jungle of infrared (IR) technology and applications available today. It explains contempoary technologies with enough detail for engineers or scientists, and with appropriate clarity and conciseness for managers.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 596 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This timely resource guides novices and experts through the jungle of infrared (IR) technology and applications available today. It explains contempoary technologies with enough detail for engineers or scientists, and with appropriate clarity and conciseness for managers. 596 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On February 15-17, 1993, a conference on Large Scale Optimization, hosted by the Center for Applied Optimization, was held at the University of Florida. The con ference was supported by the National Science Foundation, the U. S. Army Research Office, and the University of Florida, with endorsements from SIAM, MPS, ORSA and IMACS. Forty one invited speakers presented papers on mathematical program ming and optimal control topics with an emphasis on algorithm development, real world applications and numerical results. Participants from Canada, Japan, Sweden, The Netherlands, Germany, Belgium, Greece, and Denmark gave the meeting an important international component. At tendees also included representatives from IBM, American Airlines, US Air, United Parcel Serice, AT & T Bell Labs, Thinking Machines, Army High Performance Com puting Research Center, and Argonne National Laboratory. In addition, the NSF sponsored attendance of thirteen graduate students from universities in the United States and abroad. Accurate modeling of scientific problems often leads to the formulation of large scale optimization problems involving thousands of continuous and/or discrete vari ables. Large scale optimization has seen a dramatic increase in activities in the past decade. This has been a natural consequence of new algorithmic developments and of the increased power of computers. For example, decomposition ideas proposed by G. Dantzig and P. Wolfe in the 1960's, are now implement able in distributed process ing systems, and today many optimization codes have been implemented on parallel machines. 476 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The field of solid state ionics is multidisciplinary in nature. Chemists, physicists, electrochimists, and engineers all are involved in the research and development of materials, techniques, and theoretical approaches. This science is one of the great triumphs of the second part of the 20th century. For nearly a century, development of materials for solid-state ionic technology has been restricted. During the last two decades there have been remarkable advances: more materials were discovered, modem technologies were used for characterization and optimization of ionic conduction in solids, trial and error approaches were deserted for defined predictions. During the same period fundamental theories for ion conduction in solids appeared. The large explosion of solid-state ionic material science may be considered to be due to two other influences. The first aspect is related to economy and connected with energy production, storage, and utilization. There are basic problems in industrialized countries from the economical, environmental, political, and technological points of view. The possibility of storing a large amount of utilizable energy in a comparatively small volume would make a number of non-conventional intermittent energy sources of practical convenience and cost. The second aspect is related to huge increase in international relationships between researchers and exchanges of results make considerable progress between scientists; one find many institutes joined in common search programs such as the material science networks organized by EEC in the European countries. 644 pp. Englisch.