Springer us springer us mrz 2012 (287 risultati)

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With a jolt you pull your car to the side of the road, and read the job sign that can't be over one day old: New Home of ABC Inc.; General Contractor, XYZ Construction Co. You think out loud, 'I knew the property had been sold,' and your eyes roam over the real estate sign with the angled 'sold' sticker pro claiming to all that the agent has been successful. 'Thought the job would have come out on the bid list by now,' you mutter as you move back onto the road and head for your office. Later in the day you get the agent on the phone: 'Jim, how did XYZ get the ABC job I saw nothing on the builders' exchange about it.' 'John, XYZ has been negotiating with ABC for the past six weeks. They did one fine job of selling on old McDuff. Understand they just called on him out of the blue asking for a chance. They put the whole package together, plans and all.' 'Didn't that tightwad McDuff get another price, Jim ' 'Sure did; two, as a matter of fact. He asked me to get two other contractors capable of doing design-build projects. He liked XYZ better. I don't know the prices, but I really feel those boys impressed McDuff by going to him. Were you planning to bid the job ' 'Thinking about it,' you answer, trying to sound very casual. 200 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The wish for a child runs deep, as does the desire for parenthood. It is a wish that is essential to the continuance of the human species. It derives its motive power from many interrelated sources: psychobiological, sociological, historical. Yet it is a power that is changing hands. A short decade ago, Louise Brown was born. Prior to this event, human beings had begun biological life deep inside a female body. Louise Brown's birth signaled the beginning of a new era: The door to a new biotechnological world was opened, a world of artificial insemination, in vitro fertilization, surrogacy, embryo transplants, amniocentesis, gender preselection-procedures imagined but never before realized, leading perhaps to the injection of new genetic material into frozen embryos. Indeed, what had been, since Eve, an exclusively female power and prerogative has now been invaded by 20th-century biotechnology. The womb has been replaced, and sperm and egg can now be joined without love and romance. Change brings with it new questions: A complex inquiry has been generated by issues that are psychological, ethical, moral, biological, sociological, and legal. Simultaneously, and not incidentally or accidentally, gender psychology is in transi tion. As we enter an androgynous zone, cultural heroes shift, new couples emerge. Gender roles are redefined, and renegotiated, not without struggle and apprehen sion. We are approaching a new frontier-hopeful, self-conscious, and anxious. The possibilities are endless, as are the problems. 332 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Society has historically not taken a benign view of genetic disease. The laws permitting sterilization of the mentally re tarded~ and those proscribing consanguineous marriages are but two examples. Indeed as far back as the 5th-10th centuries, B.C.E., consanguineous unions were outlawed (Leviticus XVIII, 6). Case law has traditionally tended toward the conservative. It is reactive rather than directive, exerting its influence only after an individual or group has sustained injury and brought suit. In contrast, state legislatures have not been inhibited in enacting statutes. Many of their products can be characterized as hasty, unnecessary, ill-conceived, and based on the heart rather than the head. Moreover the lack of expert consultation sought has also been remarkable. One state legislature, for example, has advocated immunization for sickle cell anemia! Many others have enacted laws for the screening of inborn errors of metabolism, e.g., phenylketon uria, but have poorly defined the lines of responsibility to secure compliance. A spate of specific disease-related bills has emerged in the u.S. Congress, each seeking recognition and appropriations. Sickle cell anemia, hemophilia, Cooley's anemia and Tay-Sachs disease have been among the front-runners for support. Finally, in 1975, Congress has begun to examine an omnibus bill concerning all forms of genetic disease. The bill, termed the National Genetic Diseases Act is, however, still far from being enacted. 548 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Barry' is a seventeen-year-old single white male. He has blond hair and blue eyes, weighs 150 pounds, and is five feet eleven inches tall. He was arrested in California at age sixteen for assault and robbery. Because he was underage he was initially segregated in a one-man cell while in county jail. Then, upon admission to a state prison recep tion and classification facility, he was housed in a special dormitory for young, inexperienced inmates who would be at risk within the general population. Upon completion of his screening Barry's counselor recommended that he be sent to a penal institution reserved for the younger, more violence-prone, and hard core inmates. Barry said that he felt he would have 'prob lems' at the recommended facility, but his counselor replied, 'You won't have any problems.' Once he arrived, Barry was double-celled with a nineteen-year-old inmate who beat and anally raped him during his first night in the admission unit. Barry's cellmate continued to assault him sexually during the two weeks they were housed together. 276 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I am pleased to introduce this volume on Myoblast Transfer Therapy on behalf of the Muscular Dystrophy Association and all of its Advisory Committees. The international conference which led to this volume brought together leading basic scientists and clinical investigators for the purpose of coordinating the development of this new field in the fight against muscular dystrophy. The Muscular Dystrophy Association is the nation's most rapidly growing voluntary health agency in terms of its programs of patient care, research, and professional and public education. Success is attributable to its National Chairman, Jerry Lewis, to its effective corporate membership, and to the many physicians and scientists who give their time freely to advise on policies, to review grant applications, and to participate in meetings such as this. I should like to acknowledge a large number of other individuals to whom we are indebted: the broad segment of the American public which continually and generously supports our spectrum of services. The Muscular Dystrophy Association, next year, should raise in excess of $115,000,000. These contributions are derived from more than 10 million American families. These families are not only pledging their money but expressing their hopes that we will find answers to the tragic problem of neuromuscular disease. We are confident that the fruits of this meeting will move the frontier of research forward toward that goal. 332 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past several decades, much research effort has gone into the elucidation of the role of neuroendocrine systems as secretory and metabolic regulators of cells of a variety of organs and structures, including the testes, ovaries, adrenals, thyroid, pituitary gland, and mammary glands. However, the role of cells comprising such organs and structures in the modulation of neuroendocrine processes has received considerably less is generally less well appreciated. attention and Nonetheless, it is important that we understand the actions on neuroendocrine systems of substances that reach the brain by way of the vasculature, including hormones, cytokines, toxins, amino acids, drugs, and similar agents. In order to analyze the present state of knowledge on this topic, experimental scientists and clinicians, whose shared interests include actions of circulating agents on the brain, met at a satellite symposium of the XXXI International Congress of Physiological Sciences. This symposium, entitled Circulating Regulatory Factors and Neuroendocrine Function, was held in Smolenice Castle, Czechoslovakia, June 26-July 1, 1989, and reviews delivered at this symposium as invited presentations are published in this volume. Presentations given as free communications have been published separately and are available in Endocrinologia Experimentalis 24: 1-273, 1990. 508 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The development of an effective method of drilling oil and gas wells to depths of 3-5 km and more is a complex problem of great practical interest. 'Deep Hole Drilling With Explosives' is a distinctive and very interesting work of the engineer A. P. Ostrovskii, who more than twenty years ago, by his original suggestions, made a start in investigating the field of so-called non-bit processes of shattering rocks when drilling holes, a.nd, with his co-workers, developed a fundamentally new explosive method of drilling deep holes. This book discusses the new trend in worldwide a.pplication of explosives in technology and the national economy; it presents considerable experimental material on the effect of explosions in solid media, material that is not only interesting to specialists in mining but also to physicists. Many phenomena discussed by the author and cited in the book still await explanation, but the fact that these phenomena have been already subjected to experimental study undoubtedly adds to our knowledge of one of the most meagerly investigated areas of the science of explosions-concerning the shattering effect of explo sions on solid media. July 29, 1960 Professor M. A. Sadovskii Corresponding Member of the Academy of Sciences of the USSR 1 INTRODUCTION Together with the perfection of turbine drilling and the introduction of electrical drills in the USSR, new methods have been developed for shattering rock and drilling deep oil and gas wells without the use of a bit. 140 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is directed primarily to advanced graduate and medical students, postdoctoral trainees, and established investigators having basic research interests in neoplasia. Its content is based in part on the lecture outlines and selected histopathology laboratory components of an advanced course entitled The Pathobiology of Experimental Animal and Human Neoplasia, developed by me for the Experimental Pathology Curriculum of the Department of Pathology at the Medical College of Virginia. In this regard, an effort has been made to integrate pathology with carcinogenesis, genetics, biochemistry, and cellular and molecular biology in order to present a comprehensive and current view of the neoplastic process. For focus, emphasis is mainly being placed on the neoplastic cells themselves, and not on associated host-mediated responses. It ishoped that this book will accomplish its purpose of providing students and researchers who already possess strong but diverse basic science backgrounds with unifying concepts in tumor pathobiology, so as to stimulate new research aimed at furthering our understanding of neoplastic disease. I wish to express my appreciation and heartfelt thanks to the authors, whose individual ranges of expertise and research experience clearly bring to their respective chapters unique perspectives that easily transcend any redundancy that may be present. In addition, I am grateful to Drs. George Vennart, Saul Kay, and Fred Meier, and to Ms. Connie Wilkerson of the Department of Pathology at MCV, for their helpful comments and their review of some of the material. 608 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -My ideas for this book have been evolving over the last several years as I have been working in the animal modeling area and have seen it change rather dramatically. There have been tremendous advances, both in methodology and in conceptualization, yet the literature is scattered in journals encompassing many disciplines. In particular, there have been only very limited attempts to write about the philosophical, conceptual, and controversial issues in this field; to pull together diverse findings; and to provide some general perspective on its future. As will probably be apparent, I am a clinical psychiatrist who also has a fundamental interest in animal behavior, especially primate social behavior. I entered the field from a clinical research standpoint to devel op some animal models of depression after being stimulated to do so by Dr. William Bunney, then at the National Institute of Mental Health and now at the University of California-Irvine. The field has grown rapidly since then and there is considerable research activity. Indeed, the re search activity has grown more rapidly than our conceptualization of what animal models are and are not. Animal preparations are now available for studying specific aspects of certain types of psychopathology. Thoughtful workers in the animal modeling field no longer talk about comprehensive models but rather about more limited experimental preparations in animals for studying certain specific aspects of human psychopathology. 216 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -After thousands of clinical trials, the efficacy of psychotropic drugs in the treatment of psychiatric disorders has become well established. However, the very success of these drugs has meant that many patients with chronic illnesses will receive them for a significant part of their lifetime. Side effects and other adverse reactions are an unfortunate but unavoidable component of successful pharmacotherapy. In deed, the main emphasis in new drug development is often on the search for compounds that have fewer side effects, although no one has as yet found an effective drug without them. Therefore, it is important for clinicians to be aware of side effect reaction profiles, because they are often a major determining factor in the choice of therapy. After more than three decades of major breakthroughs in the development of psychotropic drugs, reactions to these medications are still frequently reported in the current liter ature, and information about well-known reactions is con stantly refined. This book is an attempt to systematically collect and organize this large body of data and present it in an easy-to-use form. All chapters follow the same reaction oriented logic, and each important reaction is discussed using the same consistent subdivisions. The more clinically impor tant reactions appear in the body of each chapter; the more unusual or rarely reported reactions are briefly characterized in the miscellaneous section at the end of each chapter. 188 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -IS THE TOPIC ANALOG TESTING AND DIAGNOSIS TIMELY Yes, indeed it is. Testing and Diagnosis is an important topic and fulfills a vital need for the electronic industry. The testing and diagnosis of digital electronic circuits has been successfuIly developed to the point that it can be automated. Unfortu nately, its development for analog electronic circuits is still in its Stone Age. The engineer's intuition is still the most powerful tool used in the industry! There are two reasons for this. One is that there has been no pressing need from the industry. Analog circuits are usuaIly small in size. Sometimes, the engineer's experience and intuition are sufficient to fulfill the need. The other reason is that there are no breakthrough results from academic re search to provide the industry with critical ideas to develop tools. This is not because of a lack of effort. Both academic and industrial research groups have made major efforts to look into this problem. Unfortunately, the prob lem for analog circuits is fundamentally different from and much more diffi cult than its counterpart for digital circuits. These efforts have led to some important findings, but are still not at the point of being practicaIly useful. However, these situations are now changing. The current trend for the design of VLSI chips is to use analog/digital hybrid circuits, instead of digital circuits from the past. Therefore, even Ix x Preface though the analog circuit may be small, the total circuit under testing is large. 304 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Only a small part of the numerous photochemical reactions in organic compounds result in reversible structural changes. The latter are accom panied by a change in physical properties, in particular, of electronic spectra. It is tempting to try to use this photochromic effect in various systems for controlling and regulating light fluxes and for data recording. Eventually an independent trend emerged in photochemistry - the study of the photochromism of organic compounds to establish relationships between structure and photochemical behavior, the theoretical analysis of these relationships to predict structures with pre-set photochromic parameters, and, finally, the identification of suitable areas for the application of photochromism. This monograph summarizes the results of recent studies carried out by a number of research institutions in the USSR and the GDR. Devoted to an important aspect of applied photochemistry, this monograph contains a detailed exposition of the chemical photochromes referred to briefly in the earlier editions of 'Introduction to the Photochemistry of Organic Compounds' (Khimiya Press, Moscow, 1976) and 'Photochemical Proces ses in Layers' (Khimiya Press, Moscow, 1978). 284 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Physical and spectroscopic methods have been used jointly for characterization of polymers for at least four decades. Yet, new techniques permit increasingly refined determination of polymer chemistry and morphol ogy_ The correlation of this knowledge with physical properties of polymers is helpful to planned synthesis of new products. The most prominent spectroscopic techniques through the forties and fifties were infrared and ultraviolet spectroscopy. Nuclear magnetic resonance, electron spin resonance and MOssbauer spectroscopy started making sig nificant contributions to polymer chemistry in the early sixties. Still more recently fluorescence spectroscopy and laser Raman spectroscopy have become readily appli cable to polymers and are contributing significantly to the understanding of the relationship between polymer structure and properties. Determination of the distribution of monomer se quences by molecular size has become possible through combined gel permeation chromatography and spectroscopic analysis. Fragments of polymers from chemical break down or from pyrolysis are further fractionated and structurally analyzed. The relationship between the chemistry of polymers and performance can be determined from changes in chemical structure and orientation after curing, degradation, or physical or thermal manipulation of the polymers. 292 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This set of lectures is the outgrowth of a new course in the Department of Materials Science at Stanford University. It was taught collectively by the authors of the various sections and represents an attempt to increase the awareness of students in the materials area of computer simulation techniques and potentialities. The topics often ranged far afield from the materials area; however, the total package served the intended purpose of being an initiation into the world of computer simulation and, as such, made a useful first iteration to the intended purpose. The second iteration, which is in process, deals exclusively with the materials area. The course was designed to teach students a new way to wrestle with 'systems' problems in the materials science work area that require the synthesis and interactions of several disciplines of knowledge. This course was a response to the realization that effective handling of real problems, which are essentially systems problems, is one of the most important at tributes of a graduate materials scientist. About a third of the course was devoted to the student's selected problem, in the materials area, which he simulated using the digital computer. 236 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Virus diseases continue to represent serious health problems in most parts of the world. In spite of the fact that diseases such as polio myelitis and measles have been controlled in the industrialized countries by vaccination, vaccines now in use in tropical countries have proved not to be optimal. Further research is needed to develop new vaccines that will be effective in all countries. To do so we need to understand better the immune response to different viruses so that we may be able to maxi mize the protective response of new vaccines and minimize their potential immunopathologic effect. An exciting new discovery which is now being further developed is the possibility of being able to use some viruses (e.g. vaccinia, adenoviruses, etc.), as carriers for other antigens. This may open up the way for the production of vaccines that will be inexpensive and that will confer long lasting immunity after only one injection. This meeting has also served to review our present knowledge of virus diseases which are still of great importance such as hepatitis, dengue and influenza. 320 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is based on an international symposium held during September 9-12, 1986 in Bocca di Magra, Italy. The intent of the organizers was to bring together expert practitioners of fluorescence spectroscopy, particularly as applied to biological systems, to assess recent developments in the field and discuss future directions. At the same time the meeting was intended to honor the singular and outstanding scientific career of Gregorio Weber on the occasion of his seventieth birthday. Gregorio Weber is truly the pioneer in the application of fluores cence methods to biochemistry and biophysics. A complete list of his scientific contributions to fluorescence and to protein biochemistry is beyond the scope of this preface. Suffice it to say that since his initial landmark articles on fluorescence, published in the late 1940's and early 1950's, Gregorio Weber has continued to make seminal contribu tions to both the theory and practice of fluorescence and, contrary to many who might be tempted to rest on their laurels, he shows no signs of slackening his pace. In addition to his more obvious tangible contributions to the scientific field, Gregorio Weber has made equally valuable contributions of another type. Specifically, he has had the most profound impact, both profeSSionally and personally, on generations of young scientists. 476 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1989, the American Institute of Steel Construction published the ninth edition of the Manual of Steel Construction which contains the 'Specification for Structural Steel Buildings-Allowable Stress Design (ASD) and Plastic De sign.' This current specification is completely revised in format and partly in content compared to the last one, which was published in 1978. In addition to the new specification, the ninth edition of the Manual contains completely new and revised design aids. The second edition of this book is geared to the efficient use of the afore mentioned manual. To that effect, all of the formulas, tables, and explanatory material are specifically referenced to the appropriate parts of the AISCM. Ta bles and figures from the Manual, as well as some material from the Standard Specifications for Highway Bridges, published by the American Association of State Highway and Transportation Officials (AASHTO), and from the Design of Welded Structures, published by the James F. Lincoln Arc Welding Foun dation, have been reproduced here with the permission of these organizations for the convenience of the reader. The revisions which led to the second edition of this book were performed by the first two authors, who are both experienced educators and practitioners. 536 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It was our privilege, some twenty years ago, to assemble a group of Canadian and American investigators to examine the status of research in the then newly burgeoning field of psychological stress (Appley & Trumbull, 1967). As noted, in Chapter 1 of the present volume, there has been rapid development of the area since then. The conference on which the current volume is based was designed to do three things: 1. to further update the field, 2. to bring European and other perspectives to the subject, and 3. to focus on the status of theory of stress. We believe the reader will agree that all three objectives were accom plished, though in so vast and active a field, one can never be totally satisfied. The authors included in this volume are among the leading inves tigators in the field. They represent active research centers and programs in Austria, East and West Germany, Great Britain, Israel, Sweden, and the United States. Their chapters make contributions to stress theory and methodology, inform us meaningfully of the perspectives of the various research programs they represent, and provide, collectively, a description of the dynamics of the stress process as currently emerging. 364 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the proceedings of the Sixth Symposium on Empirical Foundations of Information and Software Sciences (EFISS), which was held in Atlanta, Georgia, on October 19-21, 1988. The purpose of the symposia is to explore subjects and methods of scientific inquiry which are of common interest to information and software sciences, and to identify directions of research that would benefit from the mutual interaction of these two disciplines. The main theme of the sixth symposium was modeling in information and software engineering, with emphasis on methods and tools of modeling. The symposium covered topics such as models of individual and organizational users of information systems, methods of selecting appropriate types of models for a given type of users and a given type of tasks, deriving models from records of system usage, modeling system evolution, constructing user and task models for adaptive systems, and models of system architectures. This symposium was sponsored by the School of Information and Computer Science of the Georgia Institute of Technology and by the U.S. Army Institute for Research in Management Information, Communications, and Computer Sciences (AIRMICS). 17le Editors vii CONTENTS 1 I. KEYNOTE ADDRESS . . 500 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the most effective methods of increasing the wear resistance, hardness, surface strength and high-temperature oxidation resistance of metals and alloys is the diffusion satu ration of the surfaces by metals and nonmetals. For communicating and discussing the results of the numerous researches carried out in this field in the Department of PJ:tysicotechnical Problems of Materials Science, Academy of Sciences of the UkrSSR, a permanent Scientific Seminar was set up in 1961, which enjoys an ever-increasing popularity among specialists in this field. The present collection contains papers read at the Third Session of this Seminar, held on September 25-28, 1963. The compilers of the collection and the authors of the papers hope that its publication in the U. S. A. will enable American specialists to become acquainted with the main lines along which corresponding work is being conducted in the USSR. This should contribute to an ex change of scientific experience in this interesting field which is of such great practical impor tance. G. V. Samsonov PREFACE This collection is comprised of papers relating to the diffusion saturation of metals and to coatings of refractory compounds. The papers discuss current problems in the theory and practice of the production of diffusion coatings on metallic materials. A means of classifying the methods of diffusion saturation is proposed, and a new method is described for calculating the diffusion parameters in a heterogeneous medium. 100 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Attachment to host cells or tissues is often the first step in the establishment of bacterial infections. A complex array of recognition, attachment, and virulence factors is involved in this process, which recent research has greatly illuminated. This comprehensive and authoritative volume discusses the specific cell and tissue-specific affinities of pathogenic microorganisms, including bioinorganic surfaces such as teeth, and is an essential reference for researchers and students of host-pathogen interactions. 596 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been acknowledged that the physiological effects of dietary fiber are an exceedingly complex matter which requires a multidisciplinary research effort. The increased scientific involvement of the medical community, nutritionists, chemists and physicists is not only warranted but it has become mandatory. This is because we are entering a more advanced research phase in which the observed . in vivo effects should not be only recorded, but they should be systematically correlated with the physicochemical and analytical properties of the individual dietary fibers. The Division of Agricultural and Food Chemistry of the American Chemical Society has recognized this for some time, and has asked us to organize another International Symposium, similar to one in 1982, which would address the latest developments in this field. We decided to ask a cross section of leading experts from industrial and academic research institutions to assess the state of the art in dietary fiber, namely in the areas of the physiological effects, physicochemical attributes, and in existing and proposed analytical methods. We also felt that chemistry and physical chemistry should playa greater role in fiber research to complement and better explain the existing . in vivo data. There is a large volume of animal and human physiological and nutritional data available. Unfortunately, the generated information is frequently confusing. One reason is that this research is not conducted with well characterized compounds, but rather with loosely defined complex mixtures or entities. 340 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the proceedings of the International Conference on Prostaglandins and Lipid Metabolism in Radiation Injury held in Rockville, Maryland, on October 2-3, 1986. Over 200 persons from eight countries attended the program, which consisted of 24 oral presentations and 38 poster presentations. Forty-two of those presentations have been included in this volume. The conference was sponsored by the Armed Forces Radiobiology Research Institute, located in Bethesda, Maryland. The effects of radiation on lipid synthesis and membrane damage are aptly summarized in the first five chapters. These chapters describe the effects of radiation on lipid peroxidation of model membranes, and the role of lipid composition in mammalian cell death and in bacterial radio- and thermosensitivity. In bacteria, lipid peroxidation is not essential for radiation-induced cell death. One of the key points of the conference was the paradoxical nature of the radiobiology of eicosanoids. On the one hand, eicosanoids are mediators of damage; on the other, they are radioprotective agents. It is clear from the literature and from the data presented at the conference that both of these properties may also be observed as a consequence of radiotherapy. Some studies indicate that nonsteroidal anti-inflammatory drugs may minimize or prevent certain radiation induced damage, but other studies show no positive effect. 436 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Poisons are topics of multidisciplinary concern. The clinician and the pathologist are sensitive to instances of human poisoning. The laboratory researcher, whether pharmacologist, physiologist, or biochemist, is oriented toward molecular modes of poison action. Both clinician and researcher are eager to learn of poisons that can be used as therapeutic agents or methodological tools. This volume is an attempt to underscore the multidisciplinary charac ter of neuropoisons. Six poisons of animal origin which are receiving considerable clinical and research attention are discussed. Each poison is presented first as a clinical entity, then as a topic of investigative research, and finally as an agent useful to the study of nerve function. Because no single volume on neuropoisons can be exhaustive, an attempt at balance is offered as compensation. Two snake venoms, two marine poisons, and two bacterial toxins are presented in detail. In the sequel to this volume, attention will be focused on representative neuro poisons of plant origin. 380 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In every generation the achievements in science have served mankind. The progress accomplished by one generation stimulates the next generation to even greater achievements, which may take the form of increasing, crystallizing, or detailing existing theo ries. Other forms, generally resulting from persistence and enlight ened fortune, open new areas of investigation previously unimagined and have an impact that may be felt for many years. An example of this latter form of achievement was the prepara tion and elucidation of the structures of dicyclopentadienyliron (ferrocene, reported in 1951) dibenzenechromium iodide, triphenyl chromium tristetrahydrofuranate, and numerous olefin-metal ~-com plexes which provided an introduction to new types of chemical bonds the sigma carbon-transition metal bond and the metal ~-complex bond. Initial progress in the field of organotransition-metal chemis try followed the lines of interest generated separately by organic and inorganic chemistry. However, it is becoming increasingly clear that organotransit10n-metal chemistry is not only bridging these two fields, but also crosslinking many other fields of science. 416 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The goal of this monograph is to summarize the different quantum mechanical methods developed in the last 20 years to treat the electronic structure of polymers. Owing to the nature of the problem, these methods consist of a mixture of quantum-chemical and solid-state physical tech niques. The theory described in Part I treats, besides the Hartree-Fock problem, the electron correlation, and it has also been developed for disordered polymeric systems. Though for obvious reasons the book could not include all the existing calculations, each new method des cribed is illustrated by a few applications, with a discussion of the numerical results obtained. Far more details see the Introduction to Part I. The second part contains the theoretical calculation of different properties of polymers based on the methods systematically introduced in the first part. The properties calculated include the electronic and vibrational spectra of polymers, and the computation of their transport, magnetic, and mechanical properties. In cases where reliable ex perimental data are available, the theoretical results are compared with them. 432 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Advanced Study Institute on Field Theoretical Methods in Particle Physics was held at the Universitat Kaiserslautern in Kaiserslautern, Germany, from August 13 to August 24, 1979. Twenty invited lectures and seminar-speakers and 100 other participants attended this Institute. The contributions of most of the lecturers and seminar-speakers are contained in this volume. The revival of field theory in elementary particle physics that started about ten years ago has influenced all branches of elementary particle physics from fundamental research to pure phenomenology. The selection of field theoretical methods in part icle physics appropriate for the Institute is therefore the first task for the organizers. We decided to have constructive problems of gauge field theories and solvable models as two major areas to be covered during the Institute. If one considers the concepts and terminology currently used by pure field theorists, one notices that many of them were introduced and discussed first by pheno menologists in comparing quite elementary models directly with experimental data. For this reason, it seemed worthwhile to re serve considerable time to phenomenological field theory. The Institute was sponsored by the North Atlantic Treaty Organization whose funds made the Institute possible. It was co sponsored by the Bundes-Ministerium fur Forschung und Technologie in Bonn and the Landes-Ministerium fUr Kultus in Mainz. The City of Kaiserslautern made the Theodor Zink Museum avail able for a reception. Thanks are due in particular to its director, Dr. Dunkel. 612 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The primary purposes of this volume are: 1. To provide mental health practitioners with a current overview of our knowledge about normal parental development during pregnancy and its relation to fetal development, with particular emphasis on the impact of acute and chronic stress on these developmental processes. 2. To provide an understanding of the general state of the field of pregnancy and childbirth care both in conventional health systems and in alternative options. 3. To provide an understanding of models of consultation and liaison that are adapt ed to the special conditions of pregnancy and childbirth care, as contrasted to the more traditional modes that characterize these activities in medical and surgical hospitals. If there prove to be secondary gains as a result of pursuing these goals, so much the better. The most desirable of these would be a heightening of awareness of the mental health needs of 'pregnant families' and of the risks they incur in transition from non parenthood to parenthood, and a more effective level of primary and secondary prevention of childhood mental disorders. These latter goals are more global and perhaps even a bit grandiose. Their attainment could only be documented through a series of carefully designed research projects aimed at measuring long-range developmental outcome in children and families who have experienced appropriate and early intervention during the pregnancy period. 300 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the time since this book was written, the application of NMR in the study of polymers has continued to develop rapidly. The main trends of the work have remained as before, namely, the study of the structure of polymers, molecular motion in them, and chemical conversions of high-molecular-weight substances. How ever, as a result of the refinement of experimental techniques and development of the theory, new progress has been achieved, par ticularly in the NMR spectroscopy of polymer solutions. We therefore decided that it was worthwhile to provide an ad ditionallist of literature, covering papers published in 1965, 1966, and the beginning of 1967. By using the bibliographic directory appended to the list, the reader can readily find references to the latest literature for all sections of the book. I. Ya. Slonim A. N. Lyubimov v Preface to the Russian Edition The aim of this book is mainly to answer the questions which inevitably arise for a chemist who wishes to use NMR in his work on polymers. 380 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The basis of all immunoassays is the interaction of antibodies with antigens. The most widely used immunoassay technique is radioimmunoassay (RIA) which was first developed by Yalow and Berson in 1959. The principle of RIA is elegantly simple. It utilizes a competitve binding reaction between analytes and a radio-labeled analog of the analytes (the tracer) for anti-analyte antibodies. In addition to its exquisite specificity, extraordinary sensitivity, good accuracy and precision, ease and rapidity of assay and simplicity of assay development, the applicability of RIA to a wide variety of substances has made it one of the most powerful and versatile analytical methods of the 20th century and beyond. Millions of RIA's are being performed annually on clinical, biological and environmental samples in licensed laboratories. In order to expand the use of RIA beyond the confines of these laboratories to areas like physician's offices, patients' homes, economically less developed countries, agricultural fields, large scale and continuing screening tests for infectious diseases, it has become necessary to develop non-isotopic labels. Indeed the last fifteen years have seen the development of a great number of ingenious non-isotopic labels in immunoassay so that a whole new industry capitalizing on the potential market for non isotopic immunoassays has appeared. It is the purpose of this volume to present in depth, state-of-the-art reviews on techniques used in non-isotopic immunoassays. Topics covered include: (1) Enzyme-labeled immunoassay; (2) Luminescene immunoassay; (3) Immunoassay at liquid-solid interface; (4) Membrane immunoassay and (5) 'Particle'-mediated immunoassay. 508 pp. Englisch. …