springer us springer us okt 2006 (59 risultati)

Buch. Condizione: Neu. Neuware -Di erential evolution is one of the most recent global optimizers. Discovered in 1995 it rapidly proved its practical e ciency. This book gives you a chance to learn all about di erential evolution. On reading it you will be able to pro tably apply this reliable method to problems in your eld. Asforme,mypassionforintelligentsystemsandoptimizationbeganasfar back as during my studies at Moscow State Technical University of Bauman, the best engineering school in Russia. At that time, I was gathering material for my future thesis. Being interested in my work, the Mining School of Paris proposed that I write a dissertation in France. I hesitated some time over a choice, but my natural curiosity and taste for novelty nally prevailed. At ¿ present, Docteur ` es science en informatique de l¿EcoledesMinesdeParis,I am concentrating on the development of my own enterprise. If optimization is my vocation, my hobbies are mathematics and music. Although mathematics disciplines the mind, music is lled with emotions. While playing my favorite composition, I decided to write this book. The purpose of the book is to give, in a condensed but overview form, a description of di erential evolution. In addition, this book makes accessible to a wide audience the fruits of my long research in optimization. Namely, I laid the foundation of the universal concept of search strategies design, suitable not only for di erential evolution but for many other algorithms. Also, I introduced a principle of energetic selection, an e cient method of hybridization, and advanced paralleling techniques.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 208 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Praise for George Francis's A Topological Picturebook:Bravo to Springer for reissuing this unique and beautiful book! It not only reminds the older generation of the pleasures of doing mathematics by hand, but also shows the new generation what ``hands on'' really means. John Stillwell, University of San FranciscoThe Topological Picturebook has taught a whole generation of mathematicians to draw, to see, and to think. Tony Robbin, artist and author of Shadows of Reality: The Fourth Dimension in Relativity, Cubism, and Modern ThoughtThe classic reference for how to present topological information visually, full of amazing hand-drawn pictures of complicated surfaces. John Sullivan, Technische Universitat BerlinA Topological Picturebook lets students see topology as the original discoverers conceived it: concrete and visual, free of the formalism that burdens conventional textbooks. Jeffrey Weeks, author of The Shape of SpaceA Topological Picturebook is a visual feast for anyone concerned with mathematical images. Francis provides exquisite examples to build one's 'visualization muscles'. At the same time, he explains the underlying principles and design techniques for readers to create their own lucid drawings. George W. Hart, Stony Brook UniversityIn this collection of narrative gems and intriguing hand-drawn pictures, George Francis demonstrates the chicken-and-egg relationship, in mathematics, of image and text. Since the book was first published, the case for pictures in mathematics has been won, and now it is time to reflect on their meaning. A Topological Picturebook remains indispensable. Marjorie Senechal, Smith College and co-editor of the Mathematical IntelligencerSpringer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 216 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Lie groups has been an increasing area of focus and rich research since the middle of the 20th century. Procesi's masterful approach to Lie groups through invariants and representations gives the reader a comprehensive treatment of the classical groups along with an extensive introduction to a wide range of topics associated with Lie groups: symmetric functions, theory of algebraic forms, Lie algebras, tensor algebra and symmetry, semisimple Lie algebras, algebraic groups, group representations, invariants, Hilbert theory, and binary forms with fields ranging from pure algebra to functional analysis.Key to this unique exposition is the large amount of background material presented so the book is accessible to a reader with relatively modest mathematical background. Historical information, examples, exercises are all woven into the text.Lie Groups: An Approach through Invariants and Representations will engage a broad audience, including advanced undergraduates, graduates, mathematicians in a variety of areas from pure algebra to functional analysis and mathematical physics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 628 pp. Englisch.

Buch. Condizione: Neu. Neuware - Principles of Mathematics in Operations Research is a comprehensive survey of the mathematical concepts and principles of industrial mathematics. Its purpose is to provide students and professionals with an understanding of the fundamental mathematical principles used in Industrial Mathematics/OR in modeling problems and application solutions.All the concepts presented in each chapter have undergone the learning scrutiny of the author and his students. The conceptual relationships within the chapter material have been developed in the classroom experience working with the students' level of understanding. The illustrative material throughout the book (i.e., worked-out problems and examples of the mathematical principles) was refined for student comprehension as the manuscript developed through its iterations, and the chapter exercises are refined from the previous year's exercises. In sum, the author has carefully developed a pedagogically strong survey textbook of OR and Industrial Mathematics.

Buch. Condizione: Neu. Neuware -In the Presence of English: Media and European Youth is the realization of a project first conceived in 1991 in Hamburg, Germany where Uwe Hasebrink, Ewart Skinner, and Margie Berns, with their respective specializations in media studies, international communication, and world Englishes, met and discovered intersecting interests. In that meeting they sketched out plans for a questionnaire survey to be distributed in Hamburg schools that would investigate secondary school pupils access to and use of media, their access to and use of English, and their attitudes concerning these and related topics. A year later several hundred young people in selected schools completed the questionnaire. The findings from this initial investigation appeared in a book chapter by Hasebrink, Berns, and Skinner (1997) and were reported on at conferences in North America and Europe. Eventually Kees de Bot (The Netherlands) was inspired to join Berns and Hasebrink (Ewart Skinner had moved on to other projects). Eventually we decided to extend and refine the project by building upon its interdisciplinary and international potential. From this point on the study gained increasing momentum and scope and individual team members contributed variously to what became a major undertaking. The size and complexity of the project made it not only time intensive, but time extensive as well. With limited sources of financial support, progress was slow, at times arduous, and the gap between data collection and finished manuscript was greater than anticipated. Distribution of labor among us kept the task manageable.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 184 pp. Englisch.

Buch. Condizione: Neu. Neuware -As organizations today are linking their systems across enterprise-wide networks and VPNs as well as increasing their exposure to customers, competitors, browsers and hackers on the Internet, it becomes increasingly imperative for Web professionals to be trained in techniques for effectively protecting their sites from internal and external threats. Each connection magnifies the vulnerability to attack. With the increased connectivity to the Internet and the wide availability of automated cracking tools, organizations can no longer simply rely on operating system security to protect their valuable corporate data. Furthermore, the exploding use of Web technologies for corporate intranets and Internet sites has escalated security risks to corporate data and information systems.Practical Internet Security reveals how the Internet is paving the way for secure communications within organizations and on the public Internet. This book provides the fundamental knowledge needed to analyze risks to a system and to implement a security policy that protects information assets from potential intrusion, damage, or theft. It provides dozens of real-life scenarios and examples, as well as hands-on instruction in securing Web communications and sites. You will learn the common vulnerabilities of Web sites; as well as, how to carry out secure communications across unsecured networks. All system administrators and IT security managers will find this book an essential practical resource.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 560 pp. Englisch.

Buch. Condizione: Neu. Neuware -Electron magnetic resonance in the time domain has been greatly facilitated by the introduction of novel resonance structures and better computational tools, such as the increasingly widespread use of density-matrix formalism. This second v- ume in our series, devoted both to instrumentation and computation, addresses - plications and advances in the analysis of spin relaxation time measurements. Chapters 1 deals with the important problem of measuring spin relaxation times over a broad temporal range. The author, Dr. Sushil Misra, has worked on a wide variety of solutions to problems in this area, with respect to both experimental and theoretical aspects, and Chapter 1 summarizes much of his recent work, which was enhanced by a fruitful collaboration with the late Professor Jacques Pescia. Chapter 2 presents solutions to the problem of measuring short spin relaxation times. Again, in collaboration and tribute to the late Jacques Pescia's laboratory, part of the chapter represents a translation of the amplitude modulation technique section from a doctoral thesis by Robert Lopez in 1993 to The Paul Sabatier U- versity. Experimental data that appeared in the original thesis are placed at the end of subsections that correspond to the described technique. Chapter 3 takes up the problem of multi-frequency ENDOR and ESEEM, and illustrates how small stepwise increments of spectrometer operating parameters can enable one to better determine spin-Hamiltonian parameters via a graphical analysis.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 236 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -In recent years, cytology has played an increasingly important role in the diagnosis of disease, particularly those of neoplastic origin. It is not unusual for cytologic specimens to be the only diagnostic samples available from patients with cancer. Many ancillary tests traditionally performed on histologic material are now being performed on cytologic specimens. One such technique, immunocytochemistry (ICC), has already proved to be important in diagnostic tumor pathology.This atlas examines the value of ICC as well as its limitations in contemporary cytology. Methods have been refined and high-quality reagents are now available. As a result, technical problems no longer present a major concern in this field. This volume will briefly address the technical aspects of ICC by providing practical advice for the users and analytical aspects of ICC, including correct selection of markers for specific differential diagnoses and incorporation of results in final cytologic interpretation; illustrate the utilization of ICC in the resolution of some common diagnostic problems in fine needle aspiration and body cavity fluid cytology. ICC of undifferentiated malignant neoplasms, carcinomas of unknown origin, and most importantly its utilization in specific differential diagnoses that are based on cytomorpholoy and patient¿s clinical history is also discussed. This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Buch. Condizione: Neu. Neuware -It is still hard to believe that manipulation of a single protein on the cell surface or an interaction of two or more proteins, which at times is collectively referred to as a ¿pathway,¿ could have such a profound effect on our immune system. At present, a number of such proteins or pathways have been identi ed. These observations could only be interpreted in a way that, although tens of thousand of proteins are required for a perfectly healthy immune system, many of these pathways may work in either interconnected or linear fashion. Therefore, the combined understanding of each pathway, their interactions with other pathways, and the functional c- sequence, is a cornerstone for our interpretation of pathological basis of diseases and future treatments. It is important to stay abreast on the pace of progress, which I refer to as periodic summary of incremental and breakthrough discoveries in each pathway by the experts and the leader in the eld. The CD137 Pathway: Immunology and Diseases represents such an effort and this is the rst attempt to summarize our understanding of the CD137 pathway. The following chapters cover the majority of active areas of research in this pathway and also provide an essential resource to both the nonexperts and experts in the eld.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 148 pp. Englisch.

Buch. Condizione: Neu. Neuware -Learning Languages, Learning Life Skills offers an autobiographical reflexive approach to foreign language education. The orientation of the book is practical, containing rich descriptions of language learning situations including authentic language use and student stories.Teaching, including planning, methods, classroom work and evaluation, and case studies of 'good' language learning and how dialogue based on reminiscing can be used to promote students¿ well-being in the language classroom are described in detail. Many practical examples of how to develop autobiographical reflexive approach, based on the phenomenological philosophy, and methodology, are presented. Learning Languages, Learning Life Skills significantly enhances the communicative approach and going beyond it into a new paradigm, whereby foreign language teaching and learning are seen as foreign language education.The book offers unique ways of developing vocational language teaching as an integrated holistic approach combining language contents with vocationally relevant topics and the interactive, dialogical processes of working in language classes. Presented in a 'common sense' way and accessible to non-native English readers, Learning Languages, Learning Life Skills will be of interest to teachers as well as researchers in the areas of applied and educational linguistics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -Essays in Malting and Brewing is an original and comprehensive examination of brewing from the perspective of a real brewer. Brewing texts generally use a sequential barley-beer-bottle organization that takes the reader systematically through the various stages of beer-making in a logical and informative way. This approach adequately communicates the essential operation. However, brewers think about all of the stages in the process that might affect a single property, such as beer color. Alternatively brewers might ponder the influence of such affective agents as modification or oxygen throughout the process.Essays in Malting and Brewing departs from the traditional sequential approach to pursue brewing in the manner a brew master approaches the process. It is structured to look down the length of the process for causes and effects. Each essay discusses a problem, a beer component, or a flavor, by following how this one item arises and how it changes along the way. This is a crucial feature to bear this in mind when reading the book because this organization brings together information and ideas that are not usually presented side-by-side. The essay format allows the reader to understand how the raw materials of brewing and the way they are handled impact on process performance and product quality.This new approach to an enduring subject is essential for the informed reader interested in the malting and brewing process.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 192 pp. Englisch.

Buch. Condizione: Neu. Neuware -Customer-Oriented Optimization in Public Transportation develops models, results and algorithms for optimizing public transportation from a customer-oriented point of view. The methods used are based on graph-theoretic approaches and integer programming. The specific topics are all motivated by real-world examples which occurred in practical projects. An appendix summarizes some of the basics of optimization needed to interpret the material in the book.In detail, the topics the book covers in its three parts are as follows:1. Stop location. Does it make sense to open new stations along existing bus or railway lines If yes, in which locations The problem is modeled as a continuous covering problem. To solve it the author develops a finite dominating set and shows that efficient methods are possible if the special structure of the covering matrix is used.2. Delay management. Should a train wait for delayed feeder trains or should it depart in time The author builds up two different integer programming models and a model based on project planning methods. Properties and solution methods are developed.3. Tariff planning. Part 3 deals with the design of zone tariff systems, in which the fare is determined by the number of zones used by the passengers. The author presents a model for this problem and approaches based on clustering theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 284 pp. Englisch.

Buch. Condizione: Neu. Neuware -xv Global Supply Chain: General Strategies and Framework There are five chapters on the general strategies and framework. In 'On the Globalization of Operations and Supply Chain Strategies - A Conceptual Framework and its Applications,' Panos Kouvelis and Julie Niederhoff de scribe the forces that shape globalization and a framework to develop strate gies. The authors illustrate how the framework can be used with the case of Acrilan, an acrylic fiber manufacturer. As the emerging economies begin to mature, and the supply and demand points in a supply chain begin to shift, companies need to re-optimize the de sign of their global supply chain, so as to make the best use of their global resources. This is the subject of 'Globalization and Emerging Markets: The Challenge of Continuous Global Network Optimization,' by Peter Koudal and Douglas A. Engel. Many emerging economies have lower direct labor costs, and are so attrac tive offshoring locations. But there could be many hidden costs. The decision to offshore has to be based on a sound comprehensive analysis of the total landed costs, the tradeoffs of associated risks, and the business strategies of the company. David Pyke provides us with the approach to tackle this deci sion, and share with us his personal experience in helping companies to make such decisions, in his chapter titled 'Shanghai or Charlotte The Decision to Outsource to China and Other Low Cost Countries.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 488 pp. Englisch.

Buch. Condizione: Neu. Neuware -April 2006 Introduction Bioinformatics is at a crossroads. We work in a field that is changing every day, increasingly moving from specific solutions created by single researchers working alone or in small groups to larger, often geographically dispersed programs enabled by collaborative computing and open software. This book represents an important development, giving the reader an opportunity to discover how the use of open and reusable Java code can solve large bioinformatics problems in a software engineered and robust way. I work with one of the authors of this book every day, on the National Cancer Institute's cancer Biomedical Informatics Grid (caBIG¿) project, and I can attest that they are well suited to share with their readers both their experience in the development and use of bioinformatics software, as well as their interest in solid software engineering and interoperability. Background and history In its short history, bioinformatics has become an increasingly important part of how scientists involved in biological research go about their work. This has lead to an explosion of interest in the subject, and a similar explosion in tools and data resources for researchers to learn and use in their work. Historically, tools for bioinformatics have been idiosyncratic and are custom-developed by the end-users (or those close to them) in an iterative fashion until the specific immediate problem is solved. This has led to a balkanization of informatics systems, sometimes yielding multiple, incompatible systems at a single institution for a single application.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch.

Buch. Condizione: Neu. Neuware -Forested landscapes have provided many important testing grounds for the devel- ment and application of landscape ecological principles and methods in North America. This central role of forests in landscape ecology emerged for several reasons. Forest cover is prominent in many regions of North America, from the temperate deciduous forests of the east to the coniferous forests of the north and west. Changes in forest spatial patterns are readily apparent to the human eye¿natural disturbances and timber harvests alter the arrangement of forest age classes across the landscape and this, in turn, influences many species and ecosystem processes; land-use changes have produced profound fluctuations in forest cover over several centuries; increasing re- dential development in rural areas is often concentrated within forests; and public lands include many forested landscapes. Management actions, such as varying the amount, size, and location of harvests, also represent landscape-scale ¿experiments¿ that provide valuable opportunities for study. Finally, forest patterns are readily detectable from remote imagery, and are thus amenable to study at broad scales. For these reasons, forests have provided motivation and many opportunities for studying the complex relationships between patterns and processes in many areas. The importance of landscape-level considerations in the management and c- servation of forested landscapes has become increasingly important, and a variety of stakeholders are involved.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch.

Buch. Condizione: Neu. Neuware -Design of Systems on a Chip: Design&Test is the second of two volumes addressing the design challenges associated with new generations of the semiconductor technology. The various chapters are the compilations of tutorials presented at workshops in the recent years by prominent authors from all over the world. Technology, productivity and quality are the main aspects under consideration to establish the major requirements for the design and test of upcoming systems on a chip. In particular this second book include contributions on three different, but complementary axes: core design, computer-aided design tools and test methods. A collection of chapters deal with the heterogeneity aspect of core designs, showing the diversity of parts that may share the same substrate in a state-of-the-art system on a chip. The second part of the book discusses CAD in three different levels of design abstraction, from system level to physical design. The third part deals with test methods. The topic is addressed from different viewpoints: in terms of chip complexity, test is discussed from the core and system prospective; in terms of signal heterogeneity, the digital, mixed-signal and microsystem prospective are considered.Fault-tolerance in integrated circuits is not an exclusive concern regarding space designers or highly-reliable application engineers. Rather, designers of next generation products must cope with reduced margin noises due to technological advances. The continuous evolution of the fabrication technology process of semiconductor components, in terms of transistor geometry shrinking, power supply, speed, and logic density, has significantly reduced the reliability of very deep submicron integrated circuits, in face of the various internal and external sources of noise. The very popular Field Programmable Gate Arrays, customizable by SRAM cells, are a consequence of the integrated circuit evolution with millions of memory cells to implement the logic, embedded memories, routing, and more recently with embedded microprocessors cores. These re-programmable systems-on-chip platforms must be fault-tolerant to cope with present days requirements. This book discusses fault-tolerance techniques for SRAM-based Field Programmable Gate Arrays (FPGAs). It starts by showing the model of the problem and the upset effects in the programmable architecture. In the sequence, it shows the main fault tolerance techniques used nowadays to protect integrated circuits against errors. A large set of methods for designing fault tolerance systems in SRAM-based FPGAs is described. Some presented techniques are based on developing a new fault-tolerant architecture with new robustness FPGA elements. Other techniques are based on protecting the high-level hardware description before the synthesis in the FPGA. The reader has the flexibility of choosing the most suitable fault-tolerance technique for its project and to compare a set of fault toleranttechniques for programmable logic applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 244 pp. Englisch.

Buch. Condizione: Neu. Neuware -One of our greatest current challenges is the preservation and remediation of ecosystem integrity. This requires monitoring and assessment over large geographic areas, repeatedly over time, and cannot be practically fulfilled by field measurements alone. Remotely sensed imagery plays a crucial role by its ability to monitor large spatially continuous areas. This technology increasingly provides extensive spatial-temporal data; however, the challenge is to extract meaningful environmental information from such extensive data. This book presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA).Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 152 pp. Englisch.

Buch. Condizione: Neu. Neuware - Adaptive Techniques for Mixed Signal Sytem on Chipdiscusses the concept of adaptation in the context of analog and mixed signal design along with different adaptive architectures used to control any system parameter. The first part of the book gives an overview of the different elements that are normally used in adaptive designs including tunable elements as well as voltage, current, and time references with an emphasis on the circuit design of specific blocks such as voltage-controlled transconductors, offset comparators, and a novel technique for accurate implementation of on chip resistors. While the first part of the book addresses adaptive techniques at the circuit and block levels, the second part discusses adaptive equalization architectures employed to minimize the impact of ISI (Intersymbol Interference) on the quality of received data in high-speed wire line transceivers. It presents the implementation of a 125Mbps transceiver operating over a variable length of Category 5 (CAT-5) Ethernet cable as an example of adaptive equalizers.

Buch. Condizione: Neu. Neuware - A large number of information systems use many different individual schemas to represent data. Semantically linking these schemas is a necessary precondition to establish interoperability between agents and services. Consequently, ontology alignment and mapping for data integration has becomecentral to building a world-wide semantic web.Ontology Alignment: Bridging the Semantic Gap introduces novel methods and approaches for semantic integration. In addition to developing new methods for ontology alignment, the author provides extensive explanations of up-to-date case studies. The topic of this book, coupled with the application-focused methodology, will appeal to professionals from a number of different domains.Designed for practitioners and researchers in industry, Ontology Alignment: Bridging the Semantic Web Gap is also suitable for advanced-level students in computer science and electrical engineering.

Buch. Condizione: Neu. Neuware - In the last decade, ontologies have received much attention within computer science and related disciplines, most often as the semantic web. Ontology Learning and Population from Text: Algorithms, Evaluation and Applications discusses ontologies for the semantic web, as well as knowledge management, information retrieval, text clustering and classification, as well as natural language processing.Ontology Learning and Population from Text: Algorithms, Evaluation and Applications is structured for research scientists and practitioners in industry. This book is also suitable for graduate-level students in computer science.

Taschenbuch. Condizione: Neu. Neuware - This is a book about the frontiers of computer science that have re cently been opened by work in quantum mechanics, but it is also a book about the use of recently developed automatic programming technolo gies to explore those frontiers. The automatic programming technologies themselves issue from another interdisciplinary frontier of computer sci ence - one born of the intersection of computer science with evolution ary biology. So this is a book about two frontiers of computer science, one being used primarily for the sake of exploring the other. The selection of topics in this book was made with the intention of showing how genetic programming can be usefully applied to certain problems in quantum computing. To this end, it provides a basic intro duction to quantum computing for non-physicists and it also provides a basic introduction to genetic programming for non-computer-scientists. These treatments should be comprehensible to scientifically literate read ers who have, at minimum, a passing familiarity with undergradua- level computer science (e.g. programming concepts) and mathematics (e.g. simple linear algebra). No background in physics is assumed.

Buch. Condizione: Neu. Neuware -Even if the ¿weapons of mass destruction¿ (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic eld attracts, and merits, our intense attention. These considerations underlie the signi cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 716 pp. Englisch.

Buch. Condizione: Neu. Neuware -REGULATING AGRICULTURAL BIOTECHNOLOGY: ECONOMICS AND POLICY Chapter 1 REGULATING AGRICULTURAL BIOTECHNOLOGY: INTRODUCTION AND OVERVIEW Richard E. Just,\* David Zilberman/ and Julian M. Alston \* University of Maryland, \* University of California, Berkeley, University of California, Davis Abstract: This chapter introduces the topic of this book, drawing upon the content of its chapters. An overview is provided on the economics of technological regulation as applied to agricultural crop biotechnologies. Key elements of agricultural biotechnology regulation in the United States are summarized. Key words: agricultural biotechnologies, causes and consequences of technological regula tion, overview and synthesis 1. INTRODUCTION Agricultural biotechnologies apply modern knowledge in molecular and cell biology to produce new varieties and similar genetic materials. The use of genetically modified (GM) crop varieties has grown dramatically since they were introduced in 1995, and large portions of the land allocated to corn, soybeans, and cotton are grown with these varieties. The evidence from the United States, Canada, China, India, Brazil, and Argentina suggests that these applications of biotechnology in agriculture increase yield, reduce the use of pesticides, and save production costs.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 744 pp. Englisch.

Buch. Condizione: Neu. Neuware -The discovery of leptin by Friedman and his colleagues in 1994 was a seminal discovery in the study of metabolism, providing a new tool to study energy expenditure and appetite regulation. Early studies actively investigated many aspects of metabolism, obesity, and diabetes but it was soon evident that leptin was much more than a metabolic hormone. Today leptin, with almost 11,000 reports in the world's literature, is recognized to be important in many areas of physiology with strong suggestions for involvement in clinical conditions as well. Leptin, of course, remains of great interest in obesity and diabetes but other, previously unimagined, areas are now in the realm of leptin physiology. Perhaps leptin and its involvement in many areas of reproductive physiology may be of greatest interest outside of obesity, but other physiological arenas are becoming increasingly involved in the broader understanding of leptin and its pleiotropic functions. These areas include cardiovascular disease, bone physiology, immune regulation, and even cancer and genetics. Clinical trials have suggested other areas of leptin pharmaceutical potential beyond the original promise of obesity management. These topics and others, for the first time, have been collected in one volume as the first comprehensive review of leptin and its many actions. This area will continue to increase and is now compounded by new endocrine factors that have been elucidated in the wake of leptin's explosion onto the physiological scene.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 388 pp. Englisch.

Buch. Condizione: Neu. Neuware -Food Safety: A Practical and Case Study Approach, the first volume of the ISEKI-Food book series, discusses how food quality and safety are connected and how they play a significant role in the quality of our daily lives. Topics include methods of food preservation, food packaging, benefits and risks of microorganisms and process safety.The ISEKI-Food book series is a collection where various aspects of food safety and environmental issues are introduced and reviewed by scientists specializing in the field. In all of the books special emphasis is placed on including case studies applicable to each specific topic. The books are intended for graduate students and senior level undergraduate students as well as professionals and researchers interested in food safety and environmental issues applicable to food safety.'ISEKI-Food' is an acronym for 'Integrating Safety and Environmental Knowledge Into Food Studies'. Participants in the ISEKI-Food network, coordinated by Professor Cristina Silva at The Catholic University of Portugal, come from 29 countries in Europe and most of the institutes and universities involved with Food Science education at the university level in Europe are represented. Some international companies and non teaching institutions have also participated in the network. The main objectives of ISEKI-Food are to improve the harmonization of studies in food science and engineering in Europe and to develop and adapt food science curricula emphasizing the inclusion of safety and environmental topics.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 332 pp. Englisch.

Buch. Condizione: Neu. Neuware -This special issue of Advances in Experimental Medicine and Biology includes much of the research presented at the recent Second International Tissue Engineering Conference. Held in Crete, Greece, as part of the Aegean Conference Series, the Second International Tissue Engineering Conference was organized by Dr. Kiki Hellman of the Hellman Group, Dr. John Jansen of the Nijmegen University Medical Center, and Dr. Antonios Mikos of Rice University. The conference brought over 150 researchers from around the world to the Knossos Royal Village Conference Center in Crete from May 22 to 27, 2005. Following along the lines of the conference program, this volume is divided into seven sections, focusing on stem cells, signals, scaffolds, applied technologies, animal models, regulatory issues, as well as specific tissue engineering strategies. Both original research papers and review papers are presented. The chapters reflect a diverse group of authors, including both clinicians and academicians. Furthermore, the issue contains - pers from Asia, Australia, Europe, and North America, demonstrating the international component of the conference. The intended audience for this issue includes researchers, advanced students, and - dustrial investigators. This issue should be a useful reference for tissue engineering courses as well as for researchers developing engineered tissues for clinical applications.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 488 pp. Englisch.

Buch. Condizione: Neu. Neuware - Latency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion 'tricks' blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine.

Buch. Condizione: Neu. Neuware - As the world proceeds quickly into the Information Age, it encounters both successes and challenges, and it is well recognized that Intelligent Information Processing provides the key to the Information Age and to mastering many of these challenges. Intelligent Information Processing supports the most advanced productive tools that are said to be able to change human life and the world itself. However, the path is never a straight one and every new technology brings with it a spate of new research problems to be tackled by researchers. As such, the demand for Information Processing research is ever-increasing.This bookpresents the proceedings of the 4th IFIP International Conference on Intelligent Information Processing.This conference provides a forum for engineers and scientists in academia, university and industry to present their latest research findings in all aspects of Intelligent Information Processing.

Taschenbuch. Condizione: Neu. Neuware -The Air Spora is an illustrated guide to trapping, identifying and quantifying airborne biological particles such as fungus and plant spores and pollen. This book will be of use to anyone interested in aerobiology or studying applied aspects such as dispersal and effect of allergens, or human, animal and plant pathogens. Including a comprehensive review of what is in the air and detailing the historical development of theories leading to modern aerobiology, the book explains the fundamental processes behind airborne dispersal and techniques used to sample, identify and quantify biological particles. Methods are explained in a step-by-step guide for the use of standard air sampling devices. Although formats applicable to modern molecular and immunological techniques are described, the emphasis of the book is on simple visual identification of particles in air samples using traditional microscopy. Consequently a chapter on setting-up and using a light microscope is included, although experienced researchers can skip to chapters showing photographs of examples of the Air Spora and nine colour plates of paintings of airborne particles at a magnification of x1000.'I recommend this book to those actively running or thinking of running a pollen and spore trapping program. It will also be of value to doctors, allergists, and those teaching the basics of palynology, wishing to include a lecture or two on air spora.'David M. Jarzen, Florida Museum of Natural HistoryIn: The Newsletter of the American Association Of Stratigraphic Palynologists, 2007(40:2)Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 176 pp. Englisch.

Buch. Condizione: Neu. Neuware -Changes within the interdisciplinary field of intellectual and developmental disabilities are evolving at a rapid pace. Clinicians, academics, administrators, and a variety of mental health providers alike need easy-to-access, reliable information that enables them to stay abreast of the numerous advances in research, assessment, treatment, and service delivery within a real-world sociopolitical framework. To that end, the Handbook of Intellectual and Developmental Disabilities is an essential resource for any professional who works with this vulnerable population.This volume examines in detail the numerous advances in the field, summarizing major domains and emerging subspecialties into one eminently useful reference. Its contributors comprise a panel of the leading scientist-clinicians, who offer much-needed insight and guidance into ongoing improvements in theory and practice as well as intervention and prevention. For example, the handbook: Opens with chapters that offer a comprehensive review of current definitions, classifications, etiology, and findings on the most prevalent conditions, including cerebral palsy, pediatric brain injury, genetic syndromes, and autism spectrum disorder Provides a survey of psychological and educational service delivery systems available to people with intellectual disabilities ¿ for example, several chapters focus on explaining how agencies work, the politics of service delivery, residential versus day treatment, and program evaluation Offers a wide range of assessment and diagnostic tools and tactics, including cognitive and adaptive behavior assessments, assessing for psychopathology, developmental screening, family assessment, and forensic applications Reviews the latest evidence-based prevention and intervention strategies, from social skills training to self-harm reduction to pharmacotherapy Concludes with insightful chapters on the ethical issues socialacceptance and advocacyThe Handbook of Intellectual and Developmental Disabilities makes clear the far-reaching impact these disorders have on individuals, their families, and society in general. For clinicians, researchers, and advanced-level graduate students, this volume is a must-have resource and reference.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 748 pp. Englisch.