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Taschenbuch. Condizione: Neu. Neuware - Volume 8 of Advances in Nutritional Research deals with several topics of prime current interest in nutritional research, including the role of nutrition in hypertension, in the infections associated with protein-energy malnu trition, and in pathological conditions associated with the generation of oxygen radicals in the tissues, as well as with topics of ongoing interest. Recent research indicates that reduction of obesity, of alcohol intake, and of sodium intake by salt-sensitive individuals, are the most effective non pharmacological means of reducing high blood pressure. A new approach to therapy for infections caused by protein-energy malnutrition, based on restoration of immunocompetence by administration of thyroid and anti glucocorticoid hormones, is presented. Current research into the role of nutrition in modulating tissue damage caused by oxygen radicals generated in various pathologies is reviewed. Two chapters deal with perinatal nutrition, one with the transfer of nutrients across the placenta and the other with the energy requirements of term and preterm infants. Another dicusses methods of assessing the nutritional status of hospitalized patients. vii Contents Chapter 1. The Transfer of Nutrients across the Perfused Human Placenta . . Joseph Dands 1. Introduction. 1 2. Comments on Comparative Placentology . . . . . . . . . . .- . . 1 . 3. The Perfusion Technique . . . . . . . . . . . . . . . . . . . . 3 . . . . 4. Review of Transfer Experiments . 3 4.1. Transfer of Glutamic Acid . 3 4.2. Transfer of Riboflavin . . . . . . . . . . . . . . . -. . . 6 . . . 5. Potentials and Umltations . . . . . . . . . . . . . . . . . . . 9 . . . .References . . . . . . . . . . . . . . . . . . . . . . . . . . 10 . . . . . .

Taschenbuch. Condizione: Neu. Neuware - Advances in Solar Energy is back on schedule. Volume III contains a number of interesting reviews of the different fields in solar energy conversion. We appreciate the many encouraging comments received after the second volume appeared and have incorporated some of the suggested changes. Even though most of the reviews are invited through our editors, we are always open to suggestion about subjects of importance that are ready for a com prehensive and critical review and have not been recently covered, or about potential authors. I would like to take this opportunity to thank Professor John A. Duffie for his invaluable help in starting the Advances in Solar Energy series. Although he has recently taken full responsibility as editor-in-chief for the Solar Energy Journal, his continued assistance as a member of the Board of Editors is greatly appreciated. The diligent work of the many active editors is gratefully acknowledged and constitutes the basis for a valuable review periodical with outstanding contributions. The typesetting was done by Sandra Pruitt in the Delaware office, using the TEX-program with laser print-out. Her organization and patience in coordinating with the authors, and her technical skill and diligence in preparing the submitted copy permitted the timely and high-quality assembly of this production. We wish to commend her for efforts well beyond the call of duty. The accommodating help from Plenum Press and its production staff deserves our grateful acknowledgement.

Taschenbuch. Condizione: Neu. Neuware - This book has been written as part of a new series of scientific text-books being published by Plenum Publishing Company Limited. The scope of the series is to review a chosen topic in each volume, and in addition, to present abstracts of the most important references cited in the text. Thus allowing the reader to supplement the information contained within this book without have to refer to many additional publications. This volume is devoted to the subject of Radiation Detectors, known as Photodetectors, and particular emphasis has been placed on devices operating in the infrared region of the electromagnetic spectrum. Although some detectors which are sensitive at ultraviolet and visible wavelengths, are also described. The existence of the infrared region of the spectrum has been known for almost two hundred years but the development of detectors specifically for these wavelengths was limited for a long time due to technology limitations and difficulties in understanding and explaining the phenomena involved. Significant advances were made during World War II, when the potential military applications of being able 'to see in the dar~' were demonstrated, and this progress has been maintained during the last forty years when many major advances have been achieved, such that the use of photodetectors for both civil and military applications is now relatively common and can be inexpensive.

Taschenbuch. Condizione: Neu. Neuware - Wireless personal communications, or wireless as it is now being called, has arrived. The hype is starting to fade, and the hard work of deploying new systems and services for personal communications is underway. In the United States, the FCC propelled the wireless era from infancy to mainstream with a $7.7 billion auction of 60 MHz of radio spectrum in the 180011900 MHz band. With the largest single sale of public property in the history of mankind mostly complete, the resources of the entire world are being called upon to develop inexpensive, rapidly deployable wireless systems and sub scriber units for an industry that is adding subscribers at greater than 50% annual rate. This growth is commonplace for wireless service companies throughout the world, and in the U.S., where as many as 7 licensed wireless service providers may be competing for cellularfPCS customers within the next couple of years, differentiators in cost, qual ity, service, and coverage will become critical to customer acceptance and use. Many of these issues are discussed in the papers included in this book.

Taschenbuch. Condizione: Neu. Neuware - Very large scale integration (VLSI) technologies are now maturing with a current emphasis toward submicron structures and sophisticated applications combining digital as well as analog circuits on a single chip. Abundant examples are found on today's advanced systems for telecom munications, robotics, automotive electronics, image processing, intelli gent sensors, etc . Exciting new applications are being unveiled in the field of neural computing where the massive use of analog/digital VLSI technologies will have a significant impact. To match such a fast technological trend towards single chip ana logi digital VLSI systems, researchers worldwide have long realized the vital need of producing advanced computer aided tools for designing both digital and analog circuits and systems for silicon integration. Ar chitecture and circuit compilation, device sizing and the layout genera tion are but a few familiar tasks on the world of digital integrated circuit design which can be efficiently accomplished by matured computer aided tools. In contrast, the art of tools for designing and producing analog or even analogi digital integrated circuits is quite primitive and still lack ing the industrial penetration and acceptance already achieved by digital counterparts. In fact, analog design is commonly perceived to be one of the most knowledge-intensive design tasks and analog circuits are still designed, largely by hand, by expert intimately familiar with nuances of the target application and integrated circuit fabrication process. The techniques needed to build good analog circuits seem to exist solely as expertise invested in individual designers.

Taschenbuch. Condizione: Neu. Neuware - Cytological screening for the identification of intraepithelial neoplasia of the cervix as a precursor lesion for cervical cancer has been well established as an effective means for decreasing the incidence of invasive carcinoma. Despite these screening efforts, carcinoma of the cervix remains one of the more common malignancies in women and it is the leading cause of cancer death in many countries in the western hemisphere. It is estimated that in 1986 there will still be 14,000 new cases of invasive cancer, with 6,800 deaths in the United States alone. Unfortunately, many of these patients present with advanced disease, posing difficult management problems for the clinician responsible for their care. The treatment of early stage invasive carcinoma of the cervix (lesions confined to the cervix and vagina) remains either radical surgery, radical radiation therapy or a combination thereof This approach is extraordinarily effective in the vast majority of patients. However, there remains a subset of patients with early stage disease that are at high risk for recurrence. Dr Kjorstad (Chapter 2) has identified adenocarcinomas and adenosqua mous carcinomas as having a particularly poor prognosis. In addition, patients with more than three positive lymph nodes or with involvement of lymph nodes outside of the pelvis have a very poor prognosis. He has iden tified the CEA as a potentially predictive marker for these patients with poor prognosis, especially in patients with adenocarcinomas.

Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdividions such as lung cancer, genitouri nary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diag nosis or management of a particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good in-depth reviews of cancer topics, and published sym posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by di viding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Taschenbuch. Condizione: Neu. Neuware - After the great success of the fIrst issue of the series, the International Yearbook of Nephrology 1989, we were encouraged to proceed in our editorial venture to update nephrologists yearly, on all rapidly-changing areas of nephrology. Thus we have chosen new topics and appointed experts in the fIeld, asking them to give an objective review of the topic, up-dating the readers on the world-wide literature and providing them with a complete, accurate and up-to-date list of important, recent references. We have decided to maintain the successful format of the International Yearbook of Nephrology 1989. Thus each annual issue will be devided into sections; each section will have a different primary focus every year, depending upon what area is of greatest interest at the time. In other words, the Yearbook will remain different from the numerous books which appear every year covering all aspects of nephrology. In the Yearbooks you will fInd topics usually anavailable in nephrology textbooks. In this issue we have improved the printing quality of the book, with a more uniform format throughout the volume, despite the use of camera-ready manuscripts for direct photo-offset reproduction (a procedure mandatory for a rapid publication).

Taschenbuch. Condizione: Neu. Neuware - For a period of some fifteen years following completion of my internship training in clinical psychology (1950-1951) at the Washington University School of Medicine and my concurrent successful navigation through that school's neuroanatomy course, clinical work in neuropsychology for me and the psychologists of my generation consisted almost exclusively of trying to help our physician colleagues differentiate patients with neurologic from those with psychiatric disorders. In time, experience led all of us from the several disciplines involved in this enterprise to the conclusion that the crude diag nostic techniques available to us circa 1945-1965 had garnered us little valid information upon which to base such complex, differential diagnostic decisions. It now is gratifying to look back and review the remarkable progress that has occurred in the field of clinical neuropsychology in the four decades since I was a graduate student. In the late 1940s such pioneers as Ward Halstead, Alexander Luria, George Yacorzynski, Hans-Lukas Teuber, and Arthur Benton already were involved in clinical studies that, by the late 1960s, would markedly have improved the quality of clinical practice. However, the only psychological tests that the clinical psychologist of my immediate post-Second World War generation had as aids for the diagnosis of neurologically based conditions involving cognitive deficit were such old standbys as the Wechsler Bellevue, Rorschach, Draw A Person, Bender Gestalt, and Graham Kendall Memory for Designs Test.

Taschenbuch. Condizione: Neu. Neuware - The last volume dealing with lung cancer in this series in Cancer Treatment and Research was published in 1986 and entitled Lung Cancer: Basic and Clinical Aspects. The present book continues the outline of the previous volume by presenting up-to-date information on lung cancer in critical reviews of new important basic and clinical concepts of lung cancer. The present volume has broadened the scope by also including chapters dealing with issues such as epidemiology, prophylaxis, and histopathology of lung cancer. The content of the book thus reflects the increasing awareness of a global disease that is more and more in focus, not only scientifically but also politically. The latter fact results increasingly in changes in health legisla tion, with prevention measures influencing everyday life. The great interest in the disease is natural, considering that more than one patient dies from lung cancer every minute globally. The first chapter is from the Cancer Unit, WHO, Geneva, and describes in detail the epidemiologic features of lung cancer, which is the second most frequent cancer in the world with 660,500 new cases annually; it will soon surpass stomach cancer as the leader. Thirty-one percent of the cases occur in developing countries, where the increase is especially dramatic.

Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology text books are generally out of the date. Single papers in specialized journals are informative but seldom comprehensive; these are often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in depth reviews of cancer topics, and published symposium lectures are often the best overviewes available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. it is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genito urinary cancer, pediatric oncology, etc. Second, by asking eminent authori ties in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each optic and tumor type is covered in a volume appear ing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Taschenbuch. Condizione: Neu. Neuware - The theme of this 14th International Symposium on Blood Transfusion is closely related to the work and scientific contributions of the Dutch cryobiology pioneer Dr. Herman W. Krijnen of the Dutch Red Cross Central Laboratory. Dr. Krijnen was known and respected in the national and interna tional blood transfusion community as an extremely competent scientist and a beloved and admired colleague. Dr. Krijnen was intentionally honoured with the invitation to open this symposium on cryopreservation and low temperature biology in blood transfusion and be the guest of honour at this event. Unfortunately, Dr. Krijnen suddenly died on the first of June 1989. In honour and mem ory of Dr. Krijnen this symposium will therefore be dedicated to him. Since the lOth International Symposium on Blood Transfusion in 1985 highlighted the theme of 'Future developments in blood banking', major changes have occurred in the blood banking world. Most of these changes were forced upon the Blood Banks by the fear of spreading AIDS through contaminated donations. This not only led to the wide spread testing of blood, but also to a more appropriate counselling of the community and the blood donors in specific. Additionally, virus inacti vation techniques were introduced for those components derived from multiple donations and intended for a regular transfusion in haemophi lia patients and others.

Taschenbuch. Condizione: Neu. Neuware - The scientists and engineers of today are relentless in their continuing study and analysis of the world about us from the microcosm to the macrocosm. A central purpose of this study is to gain sufficient scientific information and insight to enable the development of both representative and useful models of the superabundance of physical processes that surround us. The engineers need these models and the associated insight in order to build the information processing systems and control systems that comprise these new and emerging technologies. Much of the early modeling work that has been done on these systems has been based on the linear time-invariant system theory and its extensive use of Fourier transform theory for both continuous and discrete systems and signals. However many of the signals arising in nature and real systems are neither stationary nor linear but tend to be concentrated in both time and frequency. Hence a new methodology is needed to take these factors properly into account.

Taschenbuch. Condizione: Neu. Neuware - Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the keys to success in the IC industry is getting a new product to market in a timely fashion and being able to produce that product with sufficient yield to be profitable. There are two ways to increase yield: by improving the control of the manufacturing process and by designing the process and the circuits in such a way as to minimize the effect of the inherent variations of the process on performance. The latter is typically referred to as 'design for manufacture' or 'statistical design'. As device sizes continue to shrink, the effects of the inherent fluctuations in the IC fabrication process will have an even more obvious effect on circuit performance. And design for manufacture will increase in importance. We have been working in the area of statistically based computer aided design for more than 13 years. During the last decade we have been working with each other, and individually with our students, to develop methods and CAD tools that can be used to improve yield during the design and manufacturing phases of IC realization. This effort has resulted in a large number of publications that have appeared in a variety of journals and conference proceedings. Thus our motivation in writing this book is to put, in one place, a description of our approach to IC yield enhancement. While the work that is contained in this book has appeared in the open literature, we have attempted to use a consistent notation throughout this book. 308 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Systems Prospects is a record of the papers presented at the first con ference organised by the United Kingdom Systems Society (UKSS), held at Thwaite Hall, Hull University (UK), on the dates 12th-15th July, 1988. The UKSS originally came together in 1978 as the Barford Group (the first meetings were held in the town of Barford), comprising academics from the four institutions that incorporated departments which primarily were con cerned with developing the theory and practice of so-called systems scienc- namely Aston University, City University, Lancaster University and the Open University. The meetings of the Barford Group were deemed to be successful, so much so that a decision was made to widen its horizons to incorporate more generally those of the United Kingdom systems community (a diffuse number of academics and practitioners) - hence the title UKSS. The society, ten years later, is extant and has achieved new levels of success in the last few years in terms of rising membership and international reputation. The membership is now drawn from a wide variety of academic and commercial and industrial organisations, and from most reaches of the nation. There is also an international contingent in the membership. It is right that there should be such diversity since the UKSS is founded on the notion of equality (of creed, sex, race, class and so on --- ). This community is 'glued' together by the Society's own publication, Systemist, as well as through workshops and now this conference. 396 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -of those problems in law which we inherit and/or retrieve in order to reconstruct and interpret in the light of legal semiotics, however defined. In addition to three main areas of underlying metaphysical assumptions there are also three main areas of possible editorial focus and these should be mentioned. The three areas of focus are: 1) the state-of-the-art of legal semiotics; 2) the dynamic, intense and exceptionally interactive quality of conference participation, and 3) the content of the papers presented which is the material of this volume. My choice of this triad of focal possibilities is to exclude the last since the papers speak for themselves and need but a brief reportorial caption. I also eliminate the second possible focus as the main focus since the discussion was not taped for editing into this volume and must remain for all those who participated a quality of scholarly meetings to be remembered, savored and hoped for. My main focus is on the 'state-of-the-art' of legal semiotics. II At the conclusion of the First Round Table on Law and Semiotics (1987) it was noted that there were no working paradigms, in Kuhn's sense, that thus far emerged but rather that several problematic areas were disclosed which warrant attention. Therefore the first concern of Legal Semiotics should be to address the surface, i. e. 384 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the second half of the twentieth century, a number of researchers have conceptualized modern society as a social system composed of differenti ated yet interrelated institutional spheres. Commonly identified institu tional spheres are the family, religion, the economy, the polity or state, medicine or health care, religion, law, and education. The institutional perspective has sometimes been linked to a structural-functional frame work; it has often been asserted that institutions must be understood as parts of a larger whole operating at the societal level. Equally important have been recent institutional theory and research focusing on the more microscopic dynamics of intrainstitutional change. The concern here has been processes governing the institutionalization of rules and practices and the formation and decline of particular social structures. Although valid and useful, neither of these perspectives has yielded a systematic comparative assessment of societal institutions. The aim of this edited volume is to meet this critical need. It brings together recent theo retical and empirical research on societal institutions in a time of rapid change. The chapters focus on how these institutions adapt to societal change and what the outcomes of these changes are. 296 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is concerned with the nature of new manufacturing technologies, such as CAD/CAM and robotics, as well as ap propriate methodologies for evaluating whether such technologies are financially and organizationally viable in particular contexts. The chapters included here were commissioned as papers for presen tation at The Wharton Conference on Productivity, Technology, and Organizational Innovation, which took place in Philadelphia on December 8 and 9 of 1983. The conference was sponsored by The University of Pennsylvania's Center for the Study of Organizational Innovation. There has been a surge of interest in the area of manufacturing over the past ten years as managers have come to realize that the operations function is critical to remaining competitive. New status has been given to factory and operations managers. New programs revitalizing manufacturing and distribution have been introduced in organizations. Corporate strategy is now explicitly considering operations and manufacturing functions. And the curricula of leading business schools are reflecting the rapidly advancing research on technology management and manufacturing operations. In spite of these important signs of progress, we are clearly just at the beginning of understanding the issues involved here. The present volume provides a state-of-the-art review of the realities of technology management and manufacturing strategy. As described in the Editor's Introduction, we address four topics: The Nature of New Manufacturing Technology, Innovation and Manufacturing Strategy, Productivity Management, and Technology Management and Organ ization. These issues are clearly very important themes for U.S. 348 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Brown Boveri Symposia are by now part of a firm!ly established tradition. This is the ninth event in a series which was initiated shortly after Corporate Research was created as a separate entity within our Company; the Symposia are held every other year. The themes to date have been: 1969 Flow Research on Blading 1971 Real-Time Control of Electric Power Systems 1973 High-Temperature Materials in Gas Turbines 1975 Nonemissive Electrooptic Displays 1977 Current Interruption in High-Voltage Networks 1979 Surges in High-Voltage Networks 1981 Semiconductor Devices for Power Conditionling 1983 Corrosion in Power Generating Equipment 1985 Computer Systems for Process Control Why have we chosen these topics At the outset we established certain selection criteria; we felt that a subject for a symposium should fulfill the following three requirements: It should characterize a part of a thoroughly scientific discipline; in other words it should describe an area of scholarly study and research. r - It should be of current interest in the sense that important results have recently been obtained and considerable research effort is presently underway in the international scientific community. - It should bear some relation to the scientific and technological activity of our Company. Let us look at the requirement 'current interest': Some of the topics on the list above have been the subject of research for several decades, some even from the - v vi FOREWORD ginning of the century. 376 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume reports the proceedings of a NATO Advanced Workshop held at Cameron House Hotel, Loch Lomond, Scotland, from May 2 - 5, 1994. The major impetus for this workshop was the realisation, over the past 7 years, that the Epstein-Barr virus is associated with a proportion of cases of Hodgkin's disease and is likely to play an aetiological role. There were four main aims of the workshop: first, to discuss the recent findings in relation to Epstein Barr virus and the aetiology of Hodgkin's disease; second, to relate these data to the epidemiology of Hodgkin's disease; third, to discuss other potential aetiological factors and finally, to discuss future directions for research into Hodgkin's disease. Leading experts in the field have contributed chapters to this volume. There is some overlap among chapters, particularly regarding Epstein-Barr virus, thereby allowing different groups to express views on similar topics. Perhaps, however, the most surprising feature of the workshop was the lack of controversy regarding the role of Epstein-Barr virus in Hodgkin's disease, an association that was treated with great scepticism at the beginning of the decade. The first three chapters, by Alexander, Taylor et al., and Levine el al., discuss the epidemiology of Hodgkin's disease with particular attention to clustering and genetic susceptibility. These chapters represent the first attempt to bring together epidemiological and molecular studies in Hodgkin's disease. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The value of studies of monotypic populations is constantly argued in bacterial ecology. The controversy itself is evidenceofthe strong awareness that bacterial activities in natural sites are not determined by the bacteria alone. At the same time, the best evidence that bacteria are influenced by environmental factors is the contrast between their behavior in laboratory cultures and their relatively subdued influence when in the presence of com petitors, predators, and fluctuating-often stressful-environmental conditions. Monotypic populations are admittedly reductionist, but are not therefore irrelevant to bacterial ecology. Quite the contrary. Without pure culture studies, our understanding of important and applicable bacterial activities-N fixation, for example-would still be z limited to what we could discern from a comparison of events in steamed vis-a-vis un heated soil. As was evident throughout the previous volume in this treatise, practically any method of studying natural bacterial communities upsets them while permitting only limited assessment of the respective qualities and quantitative contributions to total com munity activity of each type of bacterium present. Total activity itself is difficult to assess and is not dependably accomplished by any single method. This third volume comprises information regarding the properties of bacteria as they have been learned largely from pure culture studies. Its purpose is twofold: to provide readers with fundamental information regarding the cellular organization, physiological capabilities, and genetic systems of bacteria; and to connect known bacterial properties with environmental influences on them and with their influences on natural processes. 408 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The past twenty five years - roughly the period from 1960 to 1985 - have been by all measures among the most exciting and challenging times of our science. The increasing sensitivity of chemical instrumentation, the introduction of the routine use of computers for data reduction and of microprocessors for instrumental control, the wide-spread utilization of lasers, and the disappearance of traditional disciplinary boundaries between scientific fields are but a few of the examples one could cite to support the introductory contention. Almost all of these developments have had their impact on the development of Mossbauer Effect Spectroscopy into a technique par excellence for the elucidation of problems in all areas of chemistry and its associated sister sciences. Indeed, because this spectroscopy is based on fundamental phenomena in nuclear physics, is described in terms of the theory of the solid state and structural chemistry, is useful in the understanding of chemical reactivity and biological phenomena, and can serve to supplement information developed by many other experimental techniques, it has provided an unparalleled opportunity for the exchange of ideas among practitioners of a very wide variety of subfields of the physical and biological sciences. The present collection of contributions is the direct result of such an interaction. 396 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1969 the North Atlantic Treaty Organization established the Committee on the Challenges of Modern Society. Air Pollution was from the start one of the priority problems under study within the framework of the pilot studies undertaken by this Committee. The organization of a yearly symposium dealing with air pollution modeling and its application is one of the main activities within the pilot study in relation to air pollution. After being organized for five years by the United States and for five years by the Federal Republic of Germany, Belgium, represented by the Prime Minister's Office for science Policy, became responsible in 1980 for the organization of this symposium. This volume contains the papers presented at the 14th Inter national Technical Meeting on Air Pollution Modeling and its Appli cation held in Copenhagen, Denmark, from 27th to 30th September 1983. This meeting was jointly organized by the Prime Minister's Office for Science Policy, Belgium, and the National Agency of Environmental Protection, Air Pollution Laboratory, Ris~ National Laboratory, Denmark. The conference was attended by 103 partici pants and 43 papers have been presented. The members of the se lection committee of the 14th I.T.M. were A. Berger (Chairman, Belgium), W. Klug (Federal Republic of Germany), K. Demerjian (United States of America), L. Santomauro (Italy), R. Van Dop (The Netherlands), R.E. Turner (Canada), C. De Wispelaere (Coordinator, Belgium). 836 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Every year, the Federation of European Biochemical Societies sponsors a series of Advanced Courses designed to acquaint postgraduate students and young postdoctoral fellows with theoretical and practical aspects of topics of current interest in biochemistry, particularly within areas in which significant advances are being made. This volume contains the Proceedings of FEBS Advanced Course No. 88-02 held in Bari, Italy on the topic 'Organelles of Eukaryotic Cells: Molecular Structure and Interactions. ' It was a deliberate decision of the organizers not to restrict FEBS Advanced Course 88-02 to a discussion of a single organelle or a single aspect but to cover a broad area. One of the objectives of the course was to compare different organelles in order to allow the participants to discern recurrent themes which would illustrate that a basic unity exists in spite of the diversity. A second objective of the course was to acquaint the participants with the latest experimental approaches being used by in vestigators to study different organelles; this would illustrate that methodologies developed for studying the biogenesis of the structure-function relationships in one organelle can often be applied fruitfully to investi gate such aspects in other organelles. A third objective was to impress upon the participants that a study of the interaction between different organelles is intrinsic to understanding their physiological functions. This volume is divided into five sections. Part I is entitled 'Structure and Organization of Intracellular Organelles. 284 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past two decades, virus taxonomy has advanced to the point where most viruses can be classified as belonging to families, genera, or groups of related viruses. Virus classification is primarily based on chem ical and physical similarities, such as the size and shape of the virion, the nature of the genomic nucleic acid, the number and function of com ponent proteins, the presence of lipids and of additional structural fea tures, such as envelopes, and serological interrelationships. The families, genera, or groups of viruses that have been defined on the basis of such criteria by the International Committee on Taxonomy of Viruses (ICTV) will be described in some detail in this catalogue and illustrated by elec tron micrographs. In my present attempt to list most if not all well es tablished and studied viruses in alphabetical order, I have largely confined myself to identifying them only in such taxonomic terms, generally without quoting specific data reported for individual viruses. If the latter data do not at times agree closely with those given for the taxon or group, it is difficult to decide to what extent this is attributable to misclassi fication due to insufficient data and errors in the analytical procedures and descriptions, or to what extent this is an expression of Nature's free dom of choice and abhorrence of restrictive classifications. 280 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Computers have been applied to problems in chemistry and the chemical sciences since the dawn of the computer age; however, it is only in the past ten or fifteen years that we have seen the emergence of computational chemistry as a field of research in its own right. Its practitioners, computational chemists, are neither chemists who dabble in computing nor programmers who have an interest in chemistry, but computa tional scientists whose aim is to solve a wide range of chemical problems using modern computing machines. This book gives a broad overview of the methods and techniques employed by the computational chemist and of the wide range of problems to which he is applying them. It is divided into three parts. The first part records the basics of chemistry and of computational science that are essential to an understanding of the methods of computational chemistry. These methods are described in the second part of the book. In the third part, a survey is given of some areas in which the techniques of computational chemistry are being applied. As a result of the limited space available in a single volume, the areas covered are necessarily selective. Nevertheless, a sufficiently wide range of applications are described to provide the reader with a balanced overview of the many problems being attacked by computational studies in chemistry. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Second Edinburgh International Workshop was held in September, 1984 and took as its topic the coordinated regulation of gene expression. The intention of this series of workshops is to promote exchange of ideas and data between scientists and clinicians whose interests span molecular and cell biology, development and differentiation, oncology, and genetic and developmental pathologies. It is hoped that such interdisciplinary discussions may give rise to fruitful insights. The meetings are structured to give ample time for discussion after each formal presentation and culminate in a session of general discussion which is reported at the end of the volume of proceedings. We are very grateful to the participants, all of whom participated in the discussion and whose contributions were essential to the success of the meeting. Novel ideas were often put forward and explored thoroughly from different angles. We normally expect to achieve quite rapid publication of the proceedings of the meeting and are grateful to authors who produced typescripts of their contributions expeditiously, but, as may sometimes be the case with multi-author works, some contributors had difficulty in meeting schedules for submitting manuscripts or corrections of the text of the discussion, and in one case we have been unable to publish any record of the contribution. Our committment to the publication of the discussion, allowing participants to make corrections to the transcript of the session, such as insertion of references and clarification of oral contributions, has also imposed some delay. 404 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The foreword to the 'book of a meeting' is often an excuse for a paen of praise, a homily, or even an apologia - and sometimes a combination of all three. While certain traditions have been dispensed with in this volume the standard pattern for the foreword has its advantages, so here at least tradition will be adhered to - though in reverse order from that stated above. It The apologia can be dismissed briefly, for the editors have explained in their General Introduction that this is not the book of a meeting. All that remains to be added here is a description of the modus operandi. Being aware that speaking and writing are different activities requiring diffe rent presentation, each participant was asked to prepare a script for publication resembling what he would speak about only in outline. It may be that as a result the essays lack detail and are thin under some of the classical headings of scientific writing. So the reader, in turn, is asked to accept this and give his attention instead to the concepts and ideas contained therein. It may even come about that this kind of presentation will in the end result in something less ephemeral than the standard conference proceedings book. Criticism of conference proceedings and the type of meetings that give rise to these little-loved tomes is not a new phenomenom. 192 pp. Englisch.