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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the keys to success in the IC industry is getting a new product to market in a timely fashion and being able to produce that product with sufficient yield to be profitable. There are two ways to increase yield: by improving…the control of the manufacturing process and by designing the process and the circuits in such a way as to minimize the effect of the inherent variations of the process on performance. The latter is typically referred to as 'design for manufacture' or 'statistical design'. As device sizes continue to shrink, the effects of the inherent fluctuations in the IC fabrication process will have an even more obvious effect on circuit performance. And design for manufacture will increase in importance. We have been working in the area of statistically based computer aided design for more than 13 years. During the last decade we have been working with each other, and individually with our students, to develop methods and CAD tools that can be used to improve yield during the design and manufacturing phases of IC realization. This effort has resulted in a large number of publications that have appeared in a variety of journals and conference proceedings. Thus our motivation in writing this book is to put, in one place, a description of our approach to IC yield enhancement. While the work that is contained in this book has appeared in the open literature, we have attempted to use a consistent notation throughout this book. 308 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The value of studies of monotypic populations is constantly argued in bacterial ecology. The controversy itself is evidenceofthe strong awareness that bacterial activities in natural sites are not determined by the bacteria alone.…At the same time, the best evidence that bacteria are influenced by environmental factors is the contrast between their behavior in laboratory cultures and their relatively subdued influence when in the presence of com petitors, predators, and fluctuating-often stressful-environmental conditions. Monotypic populations are admittedly reductionist, but are not therefore irrelevant to bacterial ecology. Quite the contrary. Without pure culture studies, our understanding of important and applicable bacterial activities-N fixation, for example-would still be z limited to what we could discern from a comparison of events in steamed vis-a-vis un heated soil. As was evident throughout the previous volume in this treatise, practically any method of studying natural bacterial communities upsets them while permitting only limited assessment of the respective qualities and quantitative contributions to total com munity activity of each type of bacterium present. Total activity itself is difficult to assess and is not dependably accomplished by any single method. This third volume comprises information regarding the properties of bacteria as they have been learned largely from pure culture studies. Its purpose is twofold: to provide readers with fundamental information regarding the cellular organization, physiological capabilities, and genetic systems of bacteria; and to connect known bacterial properties with environmental influences on them and with their influences on natural processes. 408 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1969 the North Atlantic Treaty Organization established the Committee on the Challenges of Modern Society. Air Pollution was from the start one of the priority problems under study within the framework of the pilot studies under…taken by this Committee. The organization of a yearly symposium dealing with air pollution modeling and its application is one of the main activities within the pilot study in relation to air pollution. After being organized for five years by the United States and for five years by the Federal Republic of Germany, Belgium, represented by the Prime Minister's Office for science Policy, became responsible in 1980 for the organization of this symposium. This volume contains the papers presented at the 14th Inter national Technical Meeting on Air Pollution Modeling and its Appli cation held in Copenhagen, Denmark, from 27th to 30th September 1983. This meeting was jointly organized by the Prime Minister's Office for Science Policy, Belgium, and the National Agency of Environmental Protection, Air Pollution Laboratory, Ris~ National Laboratory, Denmark. The conference was attended by 103 partici pants and 43 papers have been presented. The members of the se lection committee of the 14th I.T.M. were A. Berger (Chairman, Belgium), W. Klug (Federal Republic of Germany), K. Demerjian (United States of America), L. Santomauro (Italy), R. Van Dop (The Netherlands), R.E. Turner (Canada), C. De Wispelaere (Coordinator, Belgium). 836 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Every year, the Federation of European Biochemical Societies sponsors a series of Advanced Courses designed to acquaint postgraduate students and young postdoctoral fellows with theoretical and practical aspects of topics of curren…t interest in biochemistry, particularly within areas in which significant advances are being made. This volume contains the Proceedings of FEBS Advanced Course No. 88-02 held in Bari, Italy on the topic 'Organelles of Eukaryotic Cells: Molecular Structure and Interactions. ' It was a deliberate decision of the organizers not to restrict FEBS Advanced Course 88-02 to a discussion of a single organelle or a single aspect but to cover a broad area. One of the objectives of the course was to compare different organelles in order to allow the participants to discern recurrent themes which would illustrate that a basic unity exists in spite of the diversity. A second objective of the course was to acquaint the participants with the latest experimental approaches being used by in vestigators to study different organelles; this would illustrate that methodologies developed for studying the biogenesis of the structure-function relationships in one organelle can often be applied fruitfully to investi gate such aspects in other organelles. A third objective was to impress upon the participants that a study of the interaction between different organelles is intrinsic to understanding their physiological functions. This volume is divided into five sections. Part I is entitled 'Structure and Organization of Intracellular Organelles. 284 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Computers have been applied to problems in chemistry and the chemical sciences since the dawn of the computer age; however, it is only in the past ten or fifteen years that we have seen the emergence of computational chemistry as a… field of research in its own right. Its practitioners, computational chemists, are neither chemists who dabble in computing nor programmers who have an interest in chemistry, but computa tional scientists whose aim is to solve a wide range of chemical problems using modern computing machines. This book gives a broad overview of the methods and techniques employed by the computational chemist and of the wide range of problems to which he is applying them. It is divided into three parts. The first part records the basics of chemistry and of computational science that are essential to an understanding of the methods of computational chemistry. These methods are described in the second part of the book. In the third part, a survey is given of some areas in which the techniques of computational chemistry are being applied. As a result of the limited space available in a single volume, the areas covered are necessarily selective. Nevertheless, a sufficiently wide range of applications are described to provide the reader with a balanced overview of the many problems being attacked by computational studies in chemistry. 248 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The foreword to the 'book of a meeting' is often an excuse for a paen of praise, a homily, or even an apologia - and sometimes a combination of all three. While certain traditions have been dispensed with in this volume the standar…d pattern for the foreword has its advantages, so here at least tradition will be adhered to - though in reverse order from that stated above. It The apologia can be dismissed briefly, for the editors have explained in their General Introduction that this is not the book of a meeting. All that remains to be added here is a description of the modus operandi. Being aware that speaking and writing are different activities requiring diffe rent presentation, each participant was asked to prepare a script for publication resembling what he would speak about only in outline. It may be that as a result the essays lack detail and are thin under some of the classical headings of scientific writing. So the reader, in turn, is asked to accept this and give his attention instead to the concepts and ideas contained therein. It may even come about that this kind of presentation will in the end result in something less ephemeral than the standard conference proceedings book. Criticism of conference proceedings and the type of meetings that give rise to these little-loved tomes is not a new phenomenom. 192 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although many pursue understanding of the relationship between protein structure and function for the thrill of pure science, the pay-off in a much broader sense is the ability to manipulate the Earth's chemistry and biology to imp…rove the quality of life for mankind. Immediately goals of this area of research include identification of the life-supporting functions of proteins, and the fundamental forces that facilitate these functions. Upon reaching these goals, we shall have the understanding to direct and the tools required to implement changes that will dramatically improve the quality of life. For example, under standing the chemical mechanism of diseases will facilitate development of new therapeutic drugs. Likewise, understanding of chemical mechanisms of plant growth will be used with biotechnology to improve food production under adverse climatic conditions. The challenge to understand details of protein structure/function relationships is enormous and requires an international effort for success. To direct the chemistry and biology of our environment in a positive sense will require efforts from bright, imaginative scientists located throughout the world. Although the emergence of FAX, e-mail, and the World Wide Web has revolutionized international communication, there remains a need for scientists located in distant parts of the world to occasionally meet face to face. 312 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -IISSC '89 was a tremendous success. A total of 635 people attended this educational forum which was dedicated to further the understanding of the design, construction and operation of the Superconducting Supercollider (SSC). A tota…l of 110 presentations and addresses were given. The topics discussed covered .all aspects of the SSC including: Magnet Technology Cryogenics Conventional Facilities Technical Systems Detectors Related Accelerator Technology Superconducting Wire/Cable ApproXimately 38% of the presentations addressed superconducting magnet technology, 16% were devoted to detector technology, 10% addressed superconducting wire/ cable, and the balance was equally split between the remaining topics. A special award was presented to Professor M. Tigner for his meritorious contribution to the Superconducting Supercollider (SSC). The award was presented on behalf of the IISSC Board of Directors. Keynote speakers included: Gerald 'Bachy, CERN Joe Barton, Representative from Texas, 6th Disctrict Ed Bingler, Exec. Director, Texas National Research Laboratory Commission James Decker, Deputy Director, Office of Energy Research, (DOE) Helen Edwards, Fermi National Accelerator Laboratory M. G. D. Gilchriese, SSC Central Design Group Robert Hunter, Director, Office of Energy Research, (DOE) Leon Lederman, Director, Fermi National Accelerator Laboratory Roy Schwitters, Director, SSC Laboratory Alvin Trivelpiece, Director, Oak Ridge National Laboratory Gus Voss, DESY Highlights of the symposium included two panel sessions. The first panel discussed the growing role of industry in accelerator technology. The second panel addressed the congressional perspective on SSe. Industrial Panel Congressional Panel J. R. Faulkner, Varian-Continental Joe Barton (R), Texas, 6th Dist. 844 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Here is the first graduate-level textbook to offer an introduction to the field of laser spectroscopy. Chapters cover a broad range of topics in detail, emphasizing the theoretical and experimental aspects of the field. This much-n…eeded text will allow students to explore current research and gain an understanding of the analytical and industrial applications of laser spectroscopy. 244 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Chemical reactions which can, on demand, be switched on and off are valuable for industrial applications. In order to make the best use ofthese reactions, it is essential to have them readily available for a research chemist. The c…hemical literature, in general, has not yet identified or grouped such reactions. However, their existence is relatively abundant. This book is meant as a survey ofthose reactions which have potential utility in industrially useful processes. These reactions are grouped under the title ofchemical release reactions which can be triggered by heat, light, electric current, etc., to release a specific compound from, or change in the physical or chemical properties of, a unimolecular reactant. The book is divided into chapters covering ways to trigger the release of certain chemicals. Each chapter is further divided into sections, each beginning with a brief introduction ofanalogies ofthe discussed reactions and of how they were used in reported industrial processes. This survey is not meant to be absolute or exhaustive but rather to be directive, to be as complete as possible, and to provide food for further thought. 300 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -When Pascal James Imperato, MD, assumed the edi - Exclusion by the New York State Departm~nt of Health of qualified laboratories from HIV testmg torship of the New York State Journal of Medicine in 198~, the acquired immunodeficien…cy syndro. me (AIDS) epI - Protection of health care workers - Responsibilities of physicians and other health care demic in the United States was already SIX years old. Dur ing the time of his editorship, two thematic issues of the workers Journal have been devoted to AIDS. In addition, a large - Public education number of original communications have been regularly - AIDS confidentiality published on the subje~t. This volume rings together The Symposium on AIDS in Washington, DC, had important articles published on AIDS m the Journal been so successful that the MSSNY, under the auspices of during 1987 and 1988. . . the task force and the Division of Governmental Affairs, In the early years of the epidemic the Medical Society of held two informational symposia for state senators and the State of New York (MSSNY) was aware that it had a assemblymen and their staffs in Albany, New York. Thes. e responsibility to both the professi ~ an~ the public to add were presented in February 1988 and. March. 1989. ,!,hIS its efforts to those already mobIlized m the attempt to effort has convinced the MSSNY that It has given legisla understand and control this tragic disease. Early on, the tors a better understanding of the overall AIDS problem. 168 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The National Center for Intermedia Transport Research (NCITR) was established at UCLA in 1982 by EPA as one of six Centers of Excellence for the study of environmental pollution problems. One of the functions undertaken by the NCIT…R has been to hold periodic workshops and to provide a forum for the discussion of current topiCS in the environmental pollution arena. To this end, two other workshops have previously been held. The first, held in November 1982, was chaired by H. R. Pruppacher, R. G. Semonin and W. G. N. Slinn on Precipitation Scavenging, Dry DepOSition and Resuspension. The second, held in January 1986, was chaired by Y. Cohen on Pollution Transport and Accumulation in a Multimedia Environment. The present workshop, chaired by D. T. Allen, Y. Cohen and I. R. Kaplan, was held on August 24-26, 1988 in Santa Monica, California. The title of the workshop was Intermedia Pollutant Transport: Modeling and Field Measurements. Approximately one hundred individuals participated and twenty five papers were given, mostly by invitation. The workshop was divided into the following four broad topiCS: 1) Transport of Pollutants from the Atmosphere, 2) Transport of Pollutants from Soils and Groundwaters, 3) Transport of Pollutants from Lakes and Oceans, and 4) Multimedia Transport of Pollutants. The last afternoon was reserved for a Panel Discussion. 312 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Oilseeds and legumes provide a significant proportion of the protein and energy requirements of the world population. This important new book provides comprehensive details of the main oil seed and legume crops focusing particularl…y on the nutritional aspects of these crops which are, or have the potential to be, more widely exploited in developing countries where are or have the potential to be, more widely exploited in developing countries where protein and energy malnutrition continue to escalate. The predicted rapid rise of populations in many world regions which are increasingly vulnerable to food shortages means that a full knowledge of the nutritional significance of available crops is vital in helping to prevent potential calamities. Food and Feed from Legumes and Oil Seeds has been written by a team of international contributors, each with direct experience of these important crops and their nutritional merits, and the editors are both international experts in the crops covered. This book will become of great value to nutritionists, food and feed scientists and technologists, agricultural scientists and all those involved with overseas developments and food aid organizations. 444 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Why Efforts to Expand the Meaning of 'Teratogen' Are Unacceptable Disagreement about nomenclature in teratology is not new. Dissent even about the very fabric of the discipline-what congenital malformations consist of-has often bee…n voiced. Time, instead of resolving such diffi culties, has sometimes worsened them. For example, in the past it was agreed that congenital malforma tions are abnormalities of structure present at birth, but differences of opinion concerning where the line between normal and abnormal was to be drawn prevailed. It was obvious that, in order to discover the causes of congenital malformations and cast strategies for their prevention, it would be necessary to have knowledge of the baseline of their frequency, and that this required uniformity of definition of terms. Since malfor mations of primary social concern are those having grave outcomes (and are, paradoxically, also the commonest ones), it is logical that such condi tions were the first consideration of investigators and were the defects whose frequency was considered to comprise the required baseline. 344 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Immunology has developed quite impressively over the past decade and perhaps very few fields in medicine or biology have grown so explosively. Completely new fields have been elucidated in depth. We recall only the definition of th…e nature and function of RLA antigens at the molecular level. the chemical and functional identification of several cytokines. and the correlation to particular immunological functions of specific epitopes present on cellular mem branes. The extensive application of immunological techniques and concepts to the neurological sciences has led to the development of neuroimmunology. a disci pline in its infancy until few years ago. In these last years. neuroimmunology has developed researches in various fields. RLA antigens were studied at the cellular level in brain samples and in CSF cells in several diseases. Cytokines. such as interleukin 1 and 2. gamma- and alpha-interferons. and tumor necrosis factor alpha. were studied at the immunohistological level and with quantitative methods in serum and CSF. With these data. new relevant insights were obtained on the molecular mechanisms underlying CNS immunological diseases. Moreover. neuroimmunological researches were carried on through the development of new and more 'specific' technologies for the study of natural and experimental diseases. the most important of which seem to be. at present. the techniques of cell cultures for cell lines specific to the CNS (oligodendrocytes. astroglia. microglia. meningeal cells. brain capillary cells and tumor cells). 180 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume comprises the proceedings of a NATO Advanced Study Institute held in Geilo, Norway, between 4 - 14 April 1989. This Institute was the tenth in a series held at Geilo on the subject of phase transitions. It was the first… to be concerned with the growing area of soft condensed matter, which is neither ordinary solids nor ordinary liquids, but somewhere in between. The Institute brought together many lecturers, students and active researchers in the field from a wide range of NATO and some non-NATO countries, with financial support principally from the NATO Scientific Affairs Division but also from Institutt for energiteknikk, the Nor wegian Research Council for Science and the Humanities (NAVF), The Nordic Institute for Theoretical Atomic Physics (NORDITA), the Norwegian Physical Society and VISTA, a reserach cooperation between the Norwegian Academy of Science and Letters and Den norske stats oljeselskap a.s (STATOIL). The organizing committee would like to thank all these contributors for their help in promoting an exciting and rewarding meeting, and in doing so are confident that they echo the appreciation also of all the participants. 50ft condensed matter is characterized by weak interactions between polyatomic constituents, by important thermal fluctuations effects, by mechanical softness and by a rich range of behaviours. The main emphasis at this Institute was on the fundamental collective physics, but prepar ation techniques and industrial applications were also considered. 404 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -I am very happy to have this opportunity to present the work of Boris Mirkin, a distinguished Russian scholar in the areas of data analysis and decision making methodologies. The monograph is devoted entirely to clustering, a disci…pline dispersed through many theoretical and application areas, from mathematical statistics and combina torial optimization to biology, sociology and organizational structures. It compiles an immense amount of research done to date, including many original Russian de velopments never presented to the international community before (for instance, cluster-by-cluster versions of the K-Means method in Chapter 4 or uniform par titioning in Chapter 5). The author's approach, approximation clustering, allows him both to systematize a great part of the discipline and to develop many in novative methods in the framework of optimization problems. The optimization methods considered are proved to be meaningful in the contexts of data analysis and clustering. The material presented in this book is quite interesting and stimulating in paradigms, clustering and optimization. On the other hand, it has a substantial application appeal. The book will be useful both to specialists and students in the fields of data analysis and clustering as well as in biology, psychology, economics, marketing research, artificial intelligence, and other scientific disciplines. Panos Pardalos, Series Editor. 448 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We present here the transcripts of lectures and talks which were delivered at the NATO ADVANCED STUDY INSTITUTE 'Electronic Structure of Complex Systems' held at the State University of Ghent, Belgium during the period July 12-23,…1982. The aim of these lectures was to highlight some of the current progress in our understanding of the electronic structure of com plex systems. A massive leap forward is obtained in bandstructure calculations with the advent of linear methods. The bandtheory also profitted tremendously from the recent developments in the density functional theories for the properties of the interacting electron gas in the presence of an external field of ions. The means of per forming fast bandstructure calculations and the confidence in the underlying potential functions have led in the past five years or so to a wealth of investigations into the electronic properties of elemental solids and compounds. The study of the trends of the electronic structure through families of materials provided invalu able insights for the prediction of new materials. The detailed study of the electronic structure of specific solids was not neglected and our present knowledge of d- and f-metals and metal hydrides was reviewed. For those systems we also investi gated the accuracy of the one electron potentials in fine detail and we complemented this with the study of small clusters of atoms where our calculations are amenable to comparison with the frontiers of quantum chemistry calculations. 816 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The International Workshops on 'The Use of Supercomputers in Theoretical Science' have become a tradition at the Univer sity of Antwerp, Belgium. The first one took place in 1984. This volume combines the proceedings of the second…work shop (December 12, 1985), of the third (June 16, 1987) and of the fourth (June 9, 1988). The principal aim of the International Workshops is to present the state-of-the-art in scientific high speed computa tion. Indeed, during the past ten years computational science has become a third methodology with merits equal to the theo retical and experimental sciences. Regretfully, access to supercomputers remains limited for academic researchers. None theless, supercomputers have become a major tool for scientists in a wide variety of scientific fields, and they lead to a realistic solution of problems that could not be solved a decade ago. It is a pleasure to thank the Belgian National Science Foundation (NFWO-FNRS) for the sponsoring of all the workshops. These workshops are organized in the framework of the Third Cy cle 'Vectorization, Parallel Processing and Supercomputers', which is also funded by the NFWO-FNRS. The other sponsor I want to thank is the University of Antwerp, where the workshops took place. The University of Antwerp (UIA), together with the NFWO-FNRS, are also the main sponsors of the ALPHA-project, which gives the scientists of Belgium the opportunity to obtain an easy supercomputer connection. 296 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The contemplation of truth and beauty is the proper object for which we were created, which calls forth the most intense desires of the soul, and of which it never tires -Hazlitt In his Nobel lecture Purcell commented that when he…saw snow in New England after the discovery of NMR, it appeared like 'heaps of protons quietly precessing in earth's magnetic field. ' If he were to make the comment in the context of how NMR is being used today, he could have conjured up an image of hydrogen, carbon, and nitrogen nuclei in proteins of an earthbound 8rganism subtly orchestrating a quiet symphony of frequencies, from 150 Hz to 2 kHz, carrying clues to the three-dimensional structure of the macromolecules. The manner in which the basic discoveries of Bloch and Purcell have led to the emergence of NMR, several decades later, as a major technique of biological and medical physics (and chemistry) is a striking example of the power of basic research. It is also a fascinating saga whereby whenever it was felt that the field had reached a plateau, new directions, new technologies, and sometimes serendipity produced new developments that revolutionized the technique and enhanced its capability. As Richard Ernst points out 'NMR is intellectually attractive, . . . the practical importance of NMR is enormous, and can justify much of the playful activities of an addicted spectroscopist' (Nobel lecture). 396 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Masters Theses in the Pure and Applied Sciences was first conceived, published, and disseminated by the Center for Information and Numerical Data Analysis and Synthesis (CINDAS)\* at Purdue University in 1957, starting its coverage… of theses with the academic year 1955. Beginning with Volume 13, the printing and dis semination phases of the activity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all concerned if the printing and distribution of the volumes were handled by an international publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Corporation of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 39 (thesis year 1994) a total of 13,953 thesis titles from 21 Canadian and 159 United States universities. We are sure that this broader base for these titles reported will greatly enhance the value of this impor tant annual reference work. While Volume 39 reports theses submitted in 1994, on occasion, certain uni versities do report theses submitted in previous years but not reported at the time. 436 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Evolutionary Biology,ofwhichthisisthetwenty-thirdvolume,continues toofferitsreadersawiderangeoforiginalarticles,reviews,andcom mentariesonevolution,inthebroadestsenseofthatterm. Thetopicsof thereviewsrangefromanthropology,molecular…evolution,andpaleo biologytoprinciplesofsystematics. Inrecentvolumes,abroadspectrumofarticleshaveappearedon suchsubjectsasbiochemicalsystematics,comparativemorphologyand embryology,evolutionaryecology,biogeography,andpaleobiology. We havealsoattemptedtoprovideaforumforconflictingideas. Articlessuch asthese,oftentoolongforstandardjournals,arethematerialfor Evo lutionary Biology. Theeditorscontinuetosolicitmanuscriptsonaninternationalscale inanefforttoseethateveryoneofthemanyfacetsofbiologicalevolution iscovered. Manuscriptsshouldbesenttoeitherofthefollowing:Max K. Hecht,DepartmentofBiology,QueensCollegeoftheCityUniversity ofNewYork,Flushing,NewYork11367,orBruceWallace,Department ofBiology,VirginiaPolytechnicInstituteandStateUniversity,Blacks burg,Virginia24061. TheeditorswishtocongratulateDr. GhilleanT. Pranceonhisnew appointmentatKewBotanicalGardensandthankhimforhiscollabo rativeeffortsineditingthepastninevolumes. TheEditors vII Contents 1. MaintenanceofaHereditaryVirus:TheSigmaVirusin PopulationsofItsHost, Drosophila melanogaster 1 Annie Fleuriet Introduction 1 FrenchPopulationsof Drosophila melanogaster. . . . . . . . . . . 2 PolymorphismofPopulations 2 CharacteristicsofWildStrainsoftheSigmaVirus 3 EffectsoftheInfectionuponCarriers. . . . . . . . . . . . . . . . . 7 ExperimentalPopulations. . . . . . . . . . . . . . . . . . . . . . . . . . 9 MaintenanceoftheVirusinFrenchNaturalPopulations. . . 12 GeographicalVariationofthe Drosophila-SigmaSystem 14 PolymorphismofPopulations 14 ViralCharacteristics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 TentativeInterpretationoftheGeographicalPatternObserved 18 OtherSystemsofVerticallyTransmittedViruses 22 ExistenceofDifferentSensitivitiestotheVirus 22 CharacteristicsoftheViruses. . . . . . . . . . . . . . . . . . 23 MaintenanceintheVectorPopulation 24 Appendix:TransmissionofStabilizedandNonstabilized Conditions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 Self-MaintenanceofStabilizedConditionthroughMaternal Lineage. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26 NonstabilizedCondition . . . . . . . . . . . . . . . . . . . . . . 27 References 28 2. Domestication:EvolutionaryChangeunderStress 31 M. J. Kohane and P. A. Parsons Introduction 31 EnvironmentalChangeandDomestication 33 Ix x Contents EcologicalPhenotypes 33 BehavioralPhenotypes. . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 AdaptationtoLaboratoryConditions. . . . . . . . . . . . . . . . . . . 37 ACaseStudy:DomesticationinFoxes 41 Discussion. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43 Summary. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 References 46 3. RangeExpansionandItsGeneticConsequencesinPopulationsof theGiantToad, Bufo marinus. . . . . . . . . . . . . . . . . . . . . . . . . 49 Simon Easteal Introduction 49 TheSpreadof Bufo marinus 50 TheIntroductions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50 TheAustralianRangeExpansion 52 GeneticVariationintheIntroducedPopulations. . . . . . . . . . . 58 TheData. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 GeneticVariability. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 EffectivePopulationSize 62 Dispersal,GeneFlow,andNeighborhoodSize 63 TheGeneticEffectsofRangeExpansion 64 GeographicalPatternsofVariation 74 Conclusion 81 References 82 4. EvolutionbySocialSelection. . . . . . . . . . . . . . . . . . . . . . . . . . 85 Shozo Yokoyama Introduction 85 ConceptofSocialSelection. . . . . . . . . . . . . . . . . . . . . . . . . . 86 EvidenceforSocialSelection ; . . . . . . . . . . .
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although there are over 400,000 people each year in the United States alone who suffer from traumatic injury to the central nervous system (CNS), no phar macological treatment is currently available. Considering the enormity of the… problem in terms of human tragedy as well as the economic burden to families and societies alike, it is surprising that so little effort is being made to develop treatments for these disorders. Although no one can become inured to the victims of brain or spinal cord injuries, one reason that insufficient time and effort have been devoted to research on recovery is that it is a generally held medical belief that nervous system injuries are simply not amenable to treatment. At best, current therapies are aimed at providing symptomatic relief or focus on re habilitative measures and the teaching of alternative behavioral strategies to help patients cope with their impairments, with only marginal results in many cases. Only within the last decade have neuroscientists begun to make serious inroads into understanding and examining the inherent 'plasticity' found in the adult CNS. Ten years or so ago, very few researchers or clinicians would have thought that damaged central neurons could sprout new terminals or that intact nerve fibers in a damaged pathway could proliferate to replace inputs from neurons that died as a result of injury. 412 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The expense of extending the conventional electric power utility-grid to remote loca tions (about $20,000 per mile in the U. S. ) often prohibits the installation of electric lighting, common household appliances, television receiv…ers, and other telecommuni cations equipment in such locations. Additionally, the installation of important, but perhaps seldom noticed, electronic equipment such as remote automatic weather moni toring stations, microwave telephone repeaters on mountain tops, and earth-bound navi gational aids for commercial aircraft and ships, is also impeded by the difficulty in providing electric power. The unavailability or expense of electric power in remote locations is a particularly acute problem in underdeveloped countries. The opportunity for people in these countries to improve their lives through technology will be mostly lost if they can not obtain even modest amounts of electricity. In a rural village, for example, just one or two kilowatts of electrical power can make a tremendous differ ence in the quality of life by providing refrigeration for food and medicinal storage, lighting for reading after dark, television reception, and water pumping and purifica tion. In the industrialized countries, there is the additional problem of the environmen tal burden of producing and distributing huge amounts of electricity in an economy which is always hungry for electric power. However, within the last several years, photovoltaic (i. e. , crystalline silicon solar cell) engineering has become a cost-com petitive approach for ameliorating certain difficult electrical power needs in both un derdeveloped and industrialized countries. 236 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It would be difficult to think of a more important field of study in medicine than the interaction of cells with natural and foreign surfaces, but it is rare for those in the practice of medicine and surgery to get together with th…e basic scientists to discuss what they know about it, so that ground of common interest can be explored. Perhaps the symposium should have been entitled 'Interactions between those interested in cell surfaces --- ' because it is here that the chief value of such meetings must lie. Even a brief perusal of this volume shows just how far advanced thought and work are on some facets of the topic. Some of the most pressing problems in medicine are those of tumour spread and of thrombosis of blood vessels where surface phenomena are of paramount importance. Our understanding is still very limited but, as the symposium illustrated, the answers are only to be found by study at fundamental levels, the work gaining direction and point from interaction with surgeons and others concerned with the actual disease states. 348 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Decoding the significance of proteinuria as an indicator of severity or prognosis in kidney disease is a stimulating challenge to students and practitioners of nephrology. Sir Richard Bright in 1827 associated pro with the disease…that bears his name. In the subsequent more teinuria than a century and a half, however, the meaning of the linkage between proteinuria and renal disease remains elusive. Proteinuria is discovered on routine urinalysis in about 10 million Americans, most of whom express no symptoms of kidney disease, each year. From the studies of Robinson (updated in these pages), we know that proteinuria, per se, can be present for 20 years without change in re nal function, as described in orthostatic proteinuria. By contrast, pro teinuria may be the harbinger of swift kidney destruction, rarely cul minating in clinical collapse, a syndrome typifying 'malignant proteinuria' as detailed herein by Avram. Although proteinuria is ubiquitous, an orderly management strategy for rational handling of proteinuria of less than nephrotic range is lack ing. Separation of tubular proteinuria and transient proteinuria of fever is now possible routinely. This book provides a record of the contribu tions of investigators and clinicians whose work forms the substrate for production of understanding and, ultimately, marching orders for prac titioners seeking optimized management for their proteinuric patients. 252 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In the past five years significant progress has been made in our basic and clinical under standing of Parkinson's disease. The discovery that MPTP, a relatively simple molecule, is able to induce parkinsonism in otherwise healthy a…dult humans, and the recent interest in the possibility of 'transplantation' procedures as a therapeutic modality in the treatment of Parkin son's disease have generated enormous interest in research related to Parkinson's disease. In this setting, the National Parkinson Foundation decided to organize a research meeting to bring together scientists actively engaged in research relevant to the study of Parkinson's disease, to accelerate its progress and to promote an exchange of ideas. This meeting took place in Janu ary 1988 at Key Biscayne, Florida. It was decided to publish the proceedings ofthis meeting to allow rapid documentation of the participants current findings and views regarding this rapidly of this volume follows the organization of the meeting and begins evolving field. The structure with a clinical and neuropathological review of current knowledge regarding Parkinson's dis ease. Since dopaminergic neurons playa major role in the pathophysiology of the disease, many of the contributions relate to some aspects of dopaminergic function including localiza tion, regulation, and pharmacology of dopamine receptors. A special effort has been made to provide a summary of the present knowledge of the cellular biology of the dopaminergic neurons. 244 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From July 31 through August 3,1997, the Pennsylvania State University hosted the Topics in Number Theory Conference. The conference was organized by Ken Ono and myself. By writing the preface, I am afforded the opportunity to expre…ss my gratitude to Ken for beng the inspiring and driving force behind the whole conference. Without his energy, enthusiasm and skill the entire event would never have occurred. We are extremely grateful to the sponsors of the conference: The National Sci ence Foundation, The Penn State Conference Center and the Penn State Depart ment of Mathematics. The object in this conference was to provide a variety of presentations giving a current picture of recent, significant work in number theory. There were eight plenary lectures: H. Darmon (McGill University), 'Non-vanishing of L-functions and their derivatives modulo p. ' A. Granville (University of Georgia), 'Mean values of multiplicative functions. ' C. Pomerance (University of Georgia), 'Recent results in primality testing. ' C. Skinner (Princeton University), 'Deformations of Galois representations. ' R. Stanley (Massachusetts Institute of Technology), 'Some interesting hyperplane arrangements. ' F. Rodriguez Villegas (Princeton University), 'Modular Mahler measures. ' T. Wooley (University of Michigan), 'Diophantine problems in many variables: The role of additive number theory. ' D. Zeilberger (Temple University), 'Reverse engineering in combinatorics and number theory. ' The papers in this volume provide an accurate picture of many of the topics presented at the conference including contributions from four of the plenary lectures. 276 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The papers published herein comprise the presentations given at the eighteenth of an annual series of clinical symposia arranged under the auspices of the Eastern Pennsylvania Branch of the American Society for Microbiology. This s…ymposium allowed approximately 200 persons to gather and exchange ideas on the rapid laboratory diagnosis of infectious diseases. The institution of the Diagnosis Related Group (DRG) method for reimbursement by both government agencies and private insurance carriers has provided a financial aspect to the established clinical reasons for rapid laboratory diagnosis. Now the health of the institution, as well as the patient, is dependent on a timely diagnosis and, hopefully, cure. Accordingly, the goal of this symposium was to present the latest developments in 'same-day microbiology'. In the face of stable or diminishing resources, the laboratory director is presented with many choices. Do nucleic acid probes, non instrumental ELISA techniques, or time-resolved fluorometry have a place in his or her laboratory Should the laboratory test for newly described human pathogens such as human immunodeficiency virus or human papilloma virus Can rapid techniques supplant conventional methods Or are they merely adjunctive This symposium attempted to assist in the formulation of informed decisions. Bruce Kleger Donald Jungkind Eileen Rinks Linda A. Miller vii ACKNOWLEDGEMENTS We would like to thank the Eastern Pennsylvania Branch of t~e American Society for Microbiology for sponsoring this symposium and for making this publication possible. We especially thank the Symposium Committee for their diligent work in organizing an informative and successful symposium. 164 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains lecture notes and invited contributions presented at the NATO Advanced Study Institute and EPS Liquid State Conference on PHYSICOCHEMICAL HYDRODYNAMICS-PCH: INTERFACIAL PHENOMENA that were held July 1-15, 1986, i…n LA RABIDA (Huelva) SPAIN. Although we are aware of the difficulty in organizing the contents due to the broad and multidisciplinary aspects of PCH-Interfacial Phenomena, we have tried to accomodate papers by topics and have not followed the order in the presentation at the meetings. There is also no distinction between the ASI notes and Conference papers. We have done our best to offer a coverage as complete as possible of the field. However, we had difficulties coming from the fact that some authors were so busy that either did not find time to submit their contribution or did not have time to write a comprehensive paper. We also had to cope with very late arrivals, postdeadline valuable contributions that we felt had to be included here. Our gratitude goes to the NATO Scientific Affairs Division for its economic support and to the EPS Liquid State Committee for its sponsorship. Financial support also came from Asociacion Industrias Quimicas-Huelva (Spain), Caycit-Ministerio De Educacion Y Ciencia (Spain), Canon-Espana (Spain), Citibank-Espana (Spain), CNLS-Los Alamos Nat. Lab. (U. S. A. ), CSIC (Spain), EPS, ERT (Spain), ESA, Fotonica (Spain), IBM-Espana (Spain), Junta De Andalucia (Spain), NATO, NSF (U. S. A. ), ONR-London (U. S. A. 1132 pp. Englisch.
