Springer vienna springer dez 2011 (70 risultati)
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. Neuware -Die moderne Baustoffkunde bezieht ihr Wissen aus den Erkenntnissen der Naturwissenschaften, insbesondere aus Physik und Chemie, aus den Ergebnissen der Materialpriifung, und nicht zuletzt aus handwerklichen Erfahrungen. 1m Rahmen eines einzigen Buches ist es nattirlich schwierig, diesen kom…plexen Ge gebenheiten ausfiihrlich Rechnung zu tragen. Will man nicht zu umfassend wer den, wird daher ein Teil immer zu kurz kommen. Dieses Buch gibt eine Einfiih rung in die Grundlagen. Aus diesem Grund wurde auch der Umfang auf die fUr das Bauwesen wichtigsten und gelaufigsten Baustoffe beschrankt. Ftir ein ein gehendes Studium finden sich am Ende der einzelnen Kapitel Hinweise auf die einschlagige Literatur und auf die wichtigsten Normen. Hauptsachliches Anliegen war es, die Eigenschaften der Baustoffe in bezug auf ihre Anwendung zu betrachten. Deshalb wurde auch das Kapitel tiber die Sy stematik der Baustoffkennwerte relativ ausflihrlich gehalten. In der bautech nischen Praxis hat es sich namlich gezeigt, daB man fUr die Beurteilung einer Vielzahl von neuartigen Baustoffen mit konventionellen Kennwerten, wie z.B. Dichte, Druck~, Biegezug- oder Zugfestigkeit usw. aile in nicht mehr das Auslan gen findet. Zur technologischen Charakterisierung etlicher neuer auf dem Markt befindlicher Baustoffe ist die Kenntnis von KenngroBen aus dem Bereich der Warmetechnik, des Feuchtigkeitsschutzes, der Akustik usw. unbedingt vonnoten. In diesem Zusammenhang haben auch die Methoden der statistischen Auswer tung von Priifergebnissen besondere Bedeutung erlangt. 244 pp. Deutsch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The scientific work of Walther Birkmayer is grounded on his ability to turn what was often a mass of clinical details into the basis for a hypothesis for a new therapeutic approach toward solving the problems of a patient's illness…. Birkmayer first became known when, during the Second World War, he built up a clinic for brain injuries in Vienna, in which over 3000 patients were treated. The study of changes in the autonomic functions of the nervous system in these patients as well as the problems of rehabilitation were published in a monograph, 'Hirn verletzungen'. Consequently, this was his major scientific interest during the post-war years. His book, 'Klinik und Therapie der vegetativen Funktionsstorungen' published with W. Winkler, brought Birkmayer recognition in the German-speaking world. In 1954 he took over the Neurological Department of the Geriatric Hospital of Vienna in Lainz, where he remained until his retirement in 1975. International acclaim followed his breakthrough with the clinical application of L-DOPA in Parkinson's disease. Birkmayer, as a strong adherent to the scientific interpretation of neurological and psychiatric disease, has encouraged multidisciplinary research. This is reflected in his establishment of the former Ludwig Boltzmann Institute of Neurochemistry, in which pharmacological, biochemical and histopathological research into neuropsychiatric diseases was performed under one roof. Further to his initial work on L-DOPA, Birkmayer has been in the forefront of supplementary parkinsonian therapy using enzyme inhibitors: benserazide in 1967, unselective monoamine oxidase inhibitors in 1962 and deprenyl in 1975. 252 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Before the discovery of the 'Man in the Ice' in temporal context. On the other hand the reconstruc tion of the Iceman's life-style as derived from data September 1991, little was known about the Neolithic obtained from the site has… to be correlated with inde period in the Central Alps. Suddenly and without precedent, here was the very well preserved corpse of pendent data sets. For that purpose pollen analysis was a man who had lived more than 5,000 years ago with his performed on peat-bogs in the vicinity of the find and clothing and equipment almost intact. The discovery further afield to obtain precise data on the vegetation was not just deservedly a world-wide sensation but a cover and climate in the Neolithic. Pollen analysis was unique opportunity for the scientific community to in performed for a vertical transect extending from the vestigate the life and death of a human from such very timber line almost up to the nival zone. The results of ancient times. It opened up wholly new horizons in the analyses reveal changes to the vegetation patterns prehistoric research, and with the help of a full range caused by pastoral farming long before the time of the of modern research techniques an attempt was made Iceman. 212 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna Dez 2011, 2011
Serie: Advances and Technical Standards in Neurosurgery, Libro 15 di 40. Libro 15 di 40 - Advances and Technical Standards in Neurosurgery
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association o…f Neurosurgical Societies. This series was fust discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo KrayenbUhl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the fust part of each volume. 404 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 560 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna Dez 2011, 2011
Serie: Computational Microelectronics, Libro 6 di 17. Libro 6 di 17 - Computational Microelectronics
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To be perfect does not mean that there is nothing to add, but rather there is nothing to take away Antoine de Saint-Exupery The drift-diffusion approximation has served for more than two decades as the cornerstone for the numerical… simulation of semiconductor devices. However, the tremendous speed in the development of the semiconductor industry demands numerical simulation tools that are efficient and provide reliable results. This makes the development of a simulation tool an interdisciplinary task in which physics, numerical algorithms, and device technology merge. For the sake of an efficient code there are trade-offs between the different influencing factors. The numerical performance of a program that is highly flexible in device types and the geometries it covers certainly cannot compare with a program that is optimized for one type of device only. Very often the device is sufficiently described by a two dimensional geometry. This is the case in a MOSFET, for example, if the gate length is small compared with the gate width. In these cases the geometry reduces to the specification of a two-dimensional device. Here again the simplest geometries, which are planar or at least rectangular surfaces, will give the most efficient numerical codes. The device engineer has to decide whether this reduced description of the real device is still suitable for his purposes. 288 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -l RNA tumor viruses have become increasingly utilized in studies of cellular transformation and gene regulation. The genes of retroviruses exist in two forms; as extrachromosomal, RNA-containing, infectious particles and as DNA pro… 2 viruses stably associated with cell genes. Components from the extracellular form can be collected in large quantity and purified for the preparation of molec ular probes. These probes can be used to dissect the sequence of events required for the establishment and expression of the integrated form. Furthermore the 2 genomes of retroviruses originated from normal cell genes, genes called virogenes - The nucleic acid and protein probes isolated from these viruses are therefore useful for studying the nature and expression of this normal cell gene and in elucidating the physiological role of its products. RNA tumor viruses perhaps offer us one of the most complete sets of biochemical reagents and biological responses for examining gene regulation in vertebrates and for studying the consequences of aberrant gene regulation on cell growth in tissue culture and in animals. Further more, there is an increasing conviction that virogenes play an important role in normal development and/or differentiation (RISSER, STOCKERT and OLD, 1978). Consequently, there is a growing feeling that DNA proviruses are altered viro genes and are capable of interfering with normal development or differentiation, causing reprogrammed growth or the incapacity to specialize. 128 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -During the last annual meeting of the Austrian Society for Electron Microscopy it was decided to organize scientific symposia dealing with basic problems of cytology. If possible such symposia should be arranged in cooperation with oth…er scientific societies. We intended to arrange symposia on special fields, to be presented on several aspects by excellent scientists invited. 'Neural Transmission' was chosen as a central topic for this first symposium. The subject represents a most rapidly expanding field of research and is of particular interest to morphologists, physiologists, pharmacologists, biochemists and clinicians. We are indebted to all the invited speakers for contributing their interesting papers. I feel bound to thank once more the firm of Bender, a subsidiary company of Boehringer Ingelheim and of Arzneimittelforschung Ges. m. b. H. Wien, for the generous financial support which made possible to realize the symposium. The publication of this volume, representing the papers and discussions originally read at the symposium and elaborated by the authors in detail and more extensively, was only made possible by the generous cooperation of the Springer-Verlag Vienna.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 160 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna, Springer Vienna Dez 2011, 2011
Serie: Advances and Technical Standards in Neurosurgery, Libro 15 di 40. Libro 15 di 40 - Advances and Technical Standards in Neurosurgery
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -As an addition to the European postgraduate training system for young neurosurgeons we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Ne…urosurgical Societies. This series was fust discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo KrayenbUhl. Thus were established the principles of European co operation which have been born from the European spirit, flourished in the European Association, and have throughout been associated with this series. The fact that the English language is well on the way to becoming the international medium at European scientific conferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contributions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publi cation of any volume. Our series is not intended to compete with the publications of original scientific papers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fields and constitute the fust part of each volume.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 404 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The articles in this book summarize the work presented at the mid-term workshop of the COST (European Cooperation in the Fields of Scientific and Technical Research) action on Nanostructured Materials, which was held in October 200…1 in Limerick, Ireland.The collection gives an excellent overview of the state-of-the-art, topical research areas in this field, and the progress made by the coordinated research projects. The articles cover synthesis, physical properties and characterization of nanostructured materials, such as magnetic and ferroelectric nanoparticles, nanoparticles in biological systems, metallic nanoparticles, nanocomposites, particle-reinforced polymers, semiconductor nanoparticles and thin films. 212 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Group theoretical concepts elucidate fundamental physical phenomena, including excitation spectra of quantum systems and complex geometrical structures such as molecules and crystals. These concepts are extensively covered in numerous tex…tbooks. The aim of the present monograph is to illuminate more subtle aspects featuring group theory for quantum mechanics, that is, the concept of dynamical symmetry. Dynamical symmetry groups complement the conventional groups: their elements induce transitions between states belonging to different representations of the symmetry group of the Hamiltonian. Dynamical symmetry appears as a hidden symmetry in the hydrogen atom and quantum rotator problem, but its main role is manifested in nano and meso systems. Such systems include atomic clusters, large molecules, quantum dots attached to metallic electrodes, etc. They are expected to be the building blocks of future quantum electronic devices and information transmitting algorithms. Elucidation of the electronic properties of such systems is greatly facilitated by applying concepts of dynamical group theory. 368 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Depuis l'isolement de la creatine par CHEVREUL, en 1832, dans les extraits de viande (44) et son identification par LIEBIG, en r847, l'attention des biochimistes a porte principalement, pendant longtemps, sur le role de l'arginine…dans la production de l'uree (I28), sur le cyde de l'ureo genese (I34) et sur celui de la phosphocreatine (7I) et de la phospho arginine (r68, I69) dans la contraction musculaire. A la suite de la mise en evidence, d'une part des reactions de trans amidination expliquant la convertibilite entre l'arginine et un certain nombre de derives guanidiques (28,29,33,73,2°5, 29I, 292), et, d'autre part, du mecanisme complexe de la biosynthese de l'arginine (34, 45, 46, I95, I96) , l'importance du groupement guanidique dans la fixation et le transfert de l'azote organique est devenue beaucoup plus manifeste. Par ailleurs, l'isolement de nouvelles substances dont certaines: la phosphotaurocyamine, la phosphoglycocyamine (280-282), la phospho- 10mb ricine (270), jouent le meme role de phosphagenes que le creatine et l'argininephosphate (257), amis en evidence la part importante que les derives guanidiques prennent dans la chimie du musde. L'etude de leur biogenese a montre en outre que leur role n'est pas seulement equivalent a l'arginine dans la fixation de l'azote du groupe amidinique, mais qu'ils sont capables de jouer egalement de role de regulateurs du metabolisme azote (258). I. Structure et formation. 612 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 516 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Shelley Saunders This book offers a welcome diversity of topics covering the broader subjects of teeth and the study of teeth by anthropologists. There is an impressive array of coverage here including the history of anthropologica…l study of the teeth, morphology and structure, pathology and epidemiology, the relationship between nutrition, human behavior and the dentition, age and sex estimation from teeth, and geographic and genetic variation. Most chapter authors have provided thorough reviews of their subjects along with examples of recent analytical work and recommendations for future research. North American researchers should particularly appreciate the access to an extensive European literature cited in the individual chapter bibliographies. Physical anthropologists with even a passing interest in dental research should greet the publication of this book with pleasure since it adds to a growing list of books on how the study of teeth can tell us so much about past human populations. In addition to the archaeological applications, there is the forensic objective of dental anthropology which the editors refer to in their introduction which is dealt with in this volume. The chapters dealing with methods of sex determination, age estimation of juveniles and age estimation of adults using the teeth are exhaustive and exacting and of critical importance to both 'osteoarchaeologists' and forensic anthropologists. Authors Liversidge, Herdeg and Rosing provide very clear guidelines for the use of dental formation standards in juvenile age estimation, recommendations that are so obviously necessary at this time. 596 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna Dez 2011, 2011
Serie: CISM International Centre for Mechanical Sciences, Libro 326 di 433. Libro 326 di 433 - CISM International Centre for Mechanical Sciences
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -F. dell'Isola, L. Placidi: Variational principles are a powerful tool also for formulating field theories. - F. dell'Isola, P. Seppecher, A. Madeo: Beyond Euler-Cauchy Continua. The structure of contact actions in N-th gradient generalize…d continua: a generalization of the Cauchy tetrahedron argument. - B. Bourdin, G.A. Francfort: Fracture. - S. Gavrilyuk: Multiphase flow modeling via Hamilton's principle. - V. L. Berdichevsky: Introduction to stochastic variational problems. - A. Carcaterra: New concepts in damping generation and control: theoretical formulation and industrial applications. - F. dell'Isola, P. Seppecher, A. Madeo: Fluid shock wave generation at solid-material discontinuity surfaces in porous media.Variational methods give an efficient and elegant way to formulate and solve mathematical problems that are of interest to scientists and engineers. In this book three fundamental aspects of the variational formulation of mechanics will be presented: physical, mathematical and applicative ones. The first aspect concerns the investigation of the nature of real physical problems with the aim of finding the best variational formulation suitable to those problems. The second aspect is the study of the well-posedeness of those mathematical problems which need to be solved in order to draw previsions from the formulated models. And the third aspect is related to the direct application of variational analysis to solve real engineering problems. 368 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most com…monly used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a prominent complement to size exclusion chromatography for protein pharmaceuticals. Fractionation with FFF is gentle and preserves protein structural integrity better than existing alternatives. In the present text, different chapters are written by experts in their respective field of application, who offer comparisons between the FFF techniques and other methods for characterizing their special focus material. Practical guide-lines for successful implementation, such as choice of operating conditions, are offered in conjunction with each application. In addition to new instrumentation and approaches that address important current topics, readers are provided with an overall sense of prior (but timeless) major developments that may be overlooked in literature searches. 316 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna Dez 2011, 2011
Serie: Advances and Technical Standards in Neurosurgery, Libro 6 di 40. Libro 6 di 40 - Advances and Technical Standards in Neurosurgery
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Advances: H. Duffau: Subpial dissection and subcortical mapping with vasculature and white matter pathways preservation in surgery for brain (low grade) gliomas. - F. Scholtes, G. Brook, D. Martin: Spinal cord injury and its treatment: cu…rrent management and experimental perspectives. - M. Sindou, M. Messerer, J. Alvernia, G. Saint-Pierre: Percutaneous Biopsy through the Foramen Ovale for Parasellar lesions: Surgical anatomy, Method and Indications. - Technical Standards: C. Raftopoulos, F. Waterkeyn, E. Fomekong, T. Duprez: Percutaneous pedicle screw implantation with robotic intraoperative 2D/3D fluoroscopy for refractory low back pain. - I. Zemmoura, S. Velut, P. Francois:The choroidal fissure: anatomy and surgical implications. - I. Timofeev, T. Santarius, A.G. Kolias, P.J.A. Hutchinson: Decompressive craniectomy - operative technique and perioperative care. - S Fauser, J Zentner: Management of complex cortical dysplasia in epilepsy 204 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna Dez 2011, 2011
Serie: CISM International Centre for Mechanical Sciences, Libro 327 di 433. Libro 327 di 433 - CISM International Centre for Mechanical Sciences
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -T. Wichtmann, T. Triantafyllidis: Behaviour of granular soils under environmentally induced cyclic loads. - D. Muir Wood: Constitutive modelling. - C. di Prisco: Creep versus transient loading effects in geotechnical problems. - M. Pastor… et al.: Mathematical models for transient, dynamic and cyclic problems in geotechnical engineering. - M. Pastor: Discretization techniques for transient, dynamics and cyclic problems in geotechnical engineering: first order hyperbolic partial diffential equations. - M. Pastor et l.: Discretization techniques for transient, dynamic and cyclic problems in geotechnical engineering: second order equation. - C. di Prisco: Cyclic mechanical response of rigid bodies interacting with sand strata. - D. Muir Wood: Macroelement modelling. - M. F. Randolph: Offshore design approaches and model tests for sub-failure cyclic loading of foundations. - M.F. Randolph: Cyclic interface shearing in sand and cemented solis and application to axial response of piles. - M. F. Randolph: Evaluation of the remoulded shear strength of offshore clays and application to pipline-soil and riser-soil interaction.The book gives a comprehensive description of the mechanical response of soils (granular and cohesive materials) under cyclic loading. It provides the geotechnical engineer with the theoretical and analytical tools necessary for the evaluation of settlements developng with time under cyclic, einvironmentally idncued loads (such as wave motion, wind actions, water table level variation) and their consequences for the serviceability and durability of structures such as the shallow or deep foundations used in offshore engineering, caisson beakwaters, ballast and airport pavements and also to interpret monitoring data, obtained from both natural and artificial slopes and earth embankments, for the purposes of risk assessment and mitigation. 584 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The invention of semiconductor devices is a fairly recent one, considering classical time scales in human life. The bipolar transistor was announced in 1947, and the MOS transistor, in a practically usable manner, was demonstrated…in 1960. From these beginnings the semiconductor device field has grown rapidly. The first integrated circuits, which contained just a few devices, became commercially available in the early 1960s. Immediately thereafter an evolution has taken place so that today, less than 25 years later, the manufacture of integrated circuits with over 400.000 devices per single chip is possible. Coincident with the growth in semiconductor device development, the literature concerning semiconductor device and technology issues has literally exploded. In the last decade about 50.000 papers have been published on these subjects. The advent of so called Very-Large-Scale-Integration (VLSI) has certainly revealed the need for a better understanding of basic device behavior. The miniaturization of the single transistor, which is the major prerequisite for VLSI, nearly led to a breakdown of the classical models of semiconductor devices. 312 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based v…accines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to full potential. The study of antibody specificities and identification of protective carbohydrate epitopes lies at the heart of successful vaccine design. In addition to therapy, antibodies in general serve as diagnostic tools in medical and scientific laboratories. In this setting high affinity and exquisite specificity are important factors for their successful use. 'Anticarbohydrate Antibodies - from molecular basis to clinical application' compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications. Based on significant progress in the fields of glycoimmunology and structural biology in recent years, the book comprehensively reviews the state-of-the-art in defining the key elements of carbohydrate recognition by antibodies, the molecular mimicry of carbohydrate epitopes as well as the molecular features leading to specific and relaxed binding modes. Backed-up by a combination of modern technologies to elucidate structural details of carbohydrate-antibody interactions, biomedically important carbohydrate antigens from viral, bacterial, parasite, insect and tumor cells have been analyzed in in-depth reviews written by well-known experts in the field. Fundamental knowledge of these molecular mechanisms eventually provides a rational basis to improve efficacy of carbohydrate-based vaccines and to further refine diagnostic tools in detection of pathogens and malignant cells. 456 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The invention of semiconductor devices is a fairly recent one, considering classical time scales in human life. The bipolar transistor was announced in 1947, and the MOS transistor, in a practically usable manner, was demonstrated in 1…960. From these beginnings the semiconductor device field has grown rapidly. The first integrated circuits, which contained just a few devices, became commercially available in the early 1960s. Immediately thereafter an evolution has taken place so that today, less than 25 years later, the manufacture of integrated circuits with over 400.000 devices per single chip is possible. Coincident with the growth in semiconductor device development, the literature concerning semiconductor device and technology issues has literally exploded. In the last decade about 50.000 papers have been published on these subjects. The advent of so called Very-Large-Scale-Integration (VLSI) has certainly revealed the need for a better understanding of basic device behavior. The miniaturization of the single transistor, which is the major prerequisite for VLSI, nearly led to a breakdown of the classical models of semiconductor devices.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 312 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonl…y used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a prominent complement to size exclusion chromatography for protein pharmaceuticals. Fractionation with FFF is gentle and preserves protein structural integrity better than existing alternatives. In the present text, different chapters are written by experts in their respective field of application, who offer comparisons between the FFF techniques and other methods for characterizing their special focus material. Practical guide-lines for successful implementation, such as choice of operating conditions, are offered in conjunction with each application. In addition to new instrumentation and approaches that address important current topics, readers are provided with an overall sense of prior (but timeless) major developments that may be overlooked in literature searches.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 316 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna, Springer Dez 2011, 2011
Serie: CISM International Centre for Mechanical Sciences, Libro 326 di 433. Libro 326 di 433 - CISM International Centre for Mechanical Sciences
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -F. dell'Isola, L. Placidi: Variational principles are a powerful tool also for formulating field theories. - F. dell'Isola, P. Seppecher, A. Madeo: Beyond Euler-Cauchy Continua. The structure of contact actions in N-th gradient generalized co…ntinua: a generalization of the Cauchy tetrahedron argument. - B. Bourdin, G.A. Francfort: Fracture. - S. Gavrilyuk: Multiphase flow modeling via Hamilton's principle. - V. L. Berdichevsky: Introduction to stochastic variational problems. - A. Carcaterra: New concepts in damping generation and control: theoretical formulation and industrial applications. - F. dell'Isola, P. Seppecher, A. Madeo: Fluid shock wave generation at solid-material discontinuity surfaces in porous media.Variational methods give an efficient and elegant way to formulate and solve mathematical problems that are of interest to scientists and engineers. In this book three fundamental aspects of the variational formulation of mechanics will be presented: physical, mathematical and applicative ones.The first aspect concerns the investigation of the nature of real physical problems with the aim of finding the best variational formulation suitable to those problems. The second aspect is the study of the well-posedeness of those mathematical problems which need to be solved in order to draw previsions from the formulated models. And the third aspect is related to the direct application of variational analysis to solve real engineering problems.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 368 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna, Springer Dez 2011, 2011
Serie: CISM International Centre for Mechanical Sciences, Libro 327 di 433. Libro 327 di 433 - CISM International Centre for Mechanical Sciences
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -T. Wichtmann, T. Triantafyllidis: Behaviour of granular soils under environmentally induced cyclic loads. - D. Muir Wood: Constitutive modelling. - C. di Prisco: Creep versus transient loading effects in geotechnical problems. - M. Pastor et…al.: Mathematical models for transient, dynamic and cyclic problems in geotechnical engineering. - M. Pastor: Discretization techniques for transient, dynamics and cyclic problems in geotechnical engineering: first order hyperbolic partial diffential equations. - M. Pastor et l.: Discretization techniques for transient, dynamic and cyclic problems in geotechnical engineering: second order equation. - C. di Prisco: Cyclic mechanical response of rigid bodies interacting with sand strata. - D. Muir Wood: Macroelement modelling. - M. F. Randolph: Offshore design approaches and model tests for sub-failure cyclic loading of foundations. - M.F. Randolph: Cyclic interface shearing in sand and cemented solis and application to axial response of piles. - M. F. Randolph: Evaluation of the remoulded shear strength of offshore clays and application to pipline-soil and riser-soil interaction.The book gives a comprehensive description of the mechanical response of soils (granular and cohesive materials) under cyclic loading. It provides the geotechnical engineer with the theoretical and analytical tools necessary for the evaluation of settlements developng with time under cyclic, einvironmentally idncued loads (such as wave motion, wind actions, water table level variation) and their consequences for the serviceability and durability of structures such as the shallow or deep foundations used in offshore engineering, caisson beakwaters, ballast and airport pavements and also to interpret monitoring data, obtained from both natural and artificial slopes and earth embankments, for the purposes of risk assessment and mitigation.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 584 pp. Englisch.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vacci…nes and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to full potential. The study of antibody specificities and identification of protective carbohydrate epitopes lies at the heart of successful vaccine design. In addition to therapy, antibodies in general serve as diagnostic tools in medical and scientific laboratories. In this setting high affinity and exquisite specificity are important factors for their successful use. ¿Anticarbohydrate Antibodies ¿ from molecular basis to clinical application¿ compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications. Based on significant progress in the fields of glycoimmunology and structural biology in recent years, the book comprehensively reviews the state-of-the-art in defining the key elements of carbohydrate recognition by antibodies, the molecular mimicry of carbohydrate epitopes as well as the molecular features leading to specific and relaxed binding modes. Backed-up by a combination of modern technologies to elucidate structural details of carbohydrate-antibody interactions, biomedically important carbohydrate antigens from viral, bacterial, parasite, insect and tumor cells have beenanalyzed in in-depth reviews written by well-known experts in the field. Fundamental knowledge of these molecular mechanisms eventually provides a rational basis to improve efficacy of carbohydrate-based vaccines and to further refine diagnostic tools in detection of pathogens and malignant cells.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 456 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 213,99
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis.More recently, it… has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role.In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis. 644 pp. Englisch.
Lingua: Inglese
Editore: Springer Vienna, Springer Vienna Dez 2011, 2011
Serie: Acta Neurochirurgica Supplement, Libro 15 di 91. Libro 15 di 91 - Acta Neurochirurgica Supplement
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The contributions in this volume, presented at the 5th International Hydrocephalus Workshop in May 2010 in Crete, Greece, give the present state-of-the-art in timely diagnosis and treatment of hydrocephalus.The topics covered include adva…nces in management of both pediatric and adult hydrocephalus, identifying shunt responders, clinical experiences in endoscopic third ventriculostomy, clinical trials, pathophysiology, experimental studies, and the new classification for hydrocephalus. 212 pp. Englisch.
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis.More recently, it has… become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role.In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 644 pp. Englisch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Die 'Standards der Tabakentwöhnung' wurden 2010 aktualisiert und erweitert: um neue medikamentöse und nicht-medikamentöse Therapien, wissenschaftliche Bewertungen zu jeder Maßnahme und neue Themen wie Tabakentwöhnung bei Kindern, A…doleszenten und Schwangeren, bei pneumologischen, neurologischen und kardiovaskulären Krankheitsbildern sowie bei Diabetes und Stoffwechselerkrankungen. Ebenfalls ergänzt wurden Genderaspekte, Hinweise zur Gewichtsregulierung und zur Alkohol-Koabhängigkeit. Eine wertvolle Unterstützung für die Tabakentwöhnung. 199 pp. Deutsch.
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Gegenwartig besteht in vielen Industriezweigen, vor allem in der Elektrotechnik und Elektronik, ein groBes und wachsendes Interesse an statistischen Methoden fUr die Zu verlassigkeitsanalyse. Die Theorie bietet eine Hille von Model…len, Ansatzen und Metho den, aber sie sind vorwiegend im internationalen Schrifttum der mathematischen Statistik zu finden und deshalb dem Praktiker nicht leicht zuganglich. In den allgemein bekannten Lehrbiichern zur mathematischen Statistik sind diese Methoden kaum enthalten; denn zur Zuverlassigkeitsanalyse werden Wahrscheinlichkeitsmodelle benotigt, die in den iiblichen Anwendungen keine groBe Rolle spielen. Auch mit unvollstandigen Stichproben wird sonst selten gearbeitet. So entstand der Wunsch nach einer zusammenfassenden Darstellung der wichtigsten Methoden fUr die statistische Zuverlassigkeitsanalyse und die Auswertung von Lebensdaueruntersuchungen. Diesem Wunsch versuche ich mit dem vorliegenden Buch zu entsprechen. Zuerst muBte ich aus der Vielzahl der Konzepte und Methoden jene auswahlen, die bereits angewandt werden oder sich dafUr eignen. Was sich schlieBlich durchsetzt, hangt ja nicht nur von den theoretischen Eigenschaften eines speziellen Verfahrens ab, sondern von vielen weiteren Gesichtspunkten, wie Einfachheit und Durchsichtigkeit der heuristi schen Motivation. Ob die in diesem Sinne getroffene Auswahl gut ist, wird die kiinftige Anwendung zeigen. Ein diesbeziiglicher wichtiger Komplex wurde nicht behandelt: die belastungsabhangigen Modelle. Sie hatten den Rahmen des Buches stark erweitert. AuBerdem befindet sich die damit verbundene Methodik gegenwartig in einer so stiirmi schen Entwicklung, daB in den nachsten zwei bis drei Jahren mit entscheidenden Bei tragen zu rechnen ist, die erst spater in einem Buch aufgenommen werden konnen. 232 pp. Deutsch.
