9780199744312 - The Autisms: Molecules to Model Systems (25 risultati)

Hardback. Condizione: As new. xii + 405 pp. Dust jacket. book.

Hardcover. Condizione: Near Fine(+). Large quarto in purple and yellow illus jacket; xii, 405 pages: illustrations; 27 cm; bibliographical references and index. Contents: Introduction / Craig M. Powell & Lisa M. Monteggia -- Autism and autism spectrum disorders: clinical overview / Lisa Joseph, Sarah Spence & Audrey -- Neuroimaging in autism spectrum disorders human imaging / Mikle South, John D. Herrington, Sarah J. Patterson -- An overview of the genetics of autism spectrum disorders / Joseph D. Buxbaum -- Rett syndrome: on clinical and genetic features, and experimental models based on Mecp2 dysfunction / Gaston Calfa, Alan K. Percy and Lucas Pozzo-Miller -- Mecp2 knockout in mouse models of Rett syndrome / Megumi Adachi and Lisa M. Monteggia -- Putting into perspective the use of the Fmr1 KO mouse as a model for autism spectrum disorder / Richard Paylor -- Molecular functions of the mammalian fragile X mental retardation protein: insights into mental retardation and synaptic plasticity / Claudia Bagni & Eric Klann -- Tuberous sclerosis and autism / Dan Ehninger and Alcino J. Silva -- PTEN and autism with macrocephaly / Craig M. Powell -- SHANK gene family and autism / Craig M. Powell -- Smith-Lemli-Opitz Syndrome and role of cholesterol in autism / Geeta Sarphare, Ryan Lee, and Elaine Tierney -- Angelman syndrome / Edwin J. Weeber -- Neuroligins and neurexins: bridging the synaptic cleft in autism / Craig M. Powell & Antony A. Boucard -- Alterations of the serotonin-melatonin pathway in autism spectrum disorders: biological evidence and clinical consequences / Cecile Pagan, Richard Delorme, Jean-Marie Launay, Thomas Bourgeron -- CNTNAP2 and autism spectrum disorders / Olga Penagarikano & Daniel H. Geschwind -- Chromosome 15q11.2q13.3 aneusomies and autism spectrum disorders / David J. Wu and Carolyn Schanen -- Oxytocin and vasopressin: mechanisms for potential sex differences observed in ASD / C. Sue Carter & Suma Jacob -- FOXP2: linking language and autism / Genevieve Konopka. / "The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease. These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. Craig M. Powell and Lisa M. Monteggia provide a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments. Readership: Neuroscientists, Clinicians, Psychologists, Graduate Students, and Advanced Undergraduates." ? Publisher / Autism spectrum disorders -- Genetic aspects. Autism spectrum disorders -- Pathophysiology. Biological models. Child Development Disorders, Pervasive -- genetics Child Development Disorders, Pervasive -- physiopathology Models, Biological Troubles du spectre de l'autisme -- Aspect g?n?tique. Troubles du spectre de l'autisme -- Physiopathologie. Mod?les biologiques. Biological models. Autism spectrum disorders -- Genetic aspects. Autismus Physiologische Psychologie. Fine in near fine(+) jacket in near fine dust-jacket.

Hardcover. Condizione: New. Condizione sovraccoperta: New. First Edition. A new copy in a new dustjacket: firm, clean, square and tight with no underlining or splits.

Gebundene Ausgabe. Condizione: Gut. 405 Seiten Schutzumschlag leicht beschädigt, Buch ansonsten in sehr gutem, ungelesenem Zustand. Rechnung mit ausgewiesener MwSt. Sprache: Englisch Gewicht in Gramm: 1209.

Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condizione: New. pp. 416.

Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condizione: New. pp. 416.

Condizione: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed.

Condizione: New. pp. 416.

Condizione: New.

Condizione: New. In.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: As New. Unread book in perfect condition.

Condizione: New. Editor(s): Powell, Craig M.; Monteggia, Lisa M. Num Pages: 420 pages, Illustrations (some col.). BIC Classification: MJN; MMH; MMJ; PSAN. Category: (G) General (US: Trade). Dimension: 261 x 185 x 27. Weight in Grams: 1198. . 2012. Hardback. . . . .

Condizione: New. Editor(s): Powell, Craig M.; Monteggia, Lisa M. Num Pages: 420 pages, Illustrations (some col.). BIC Classification: MJN; MMH; MMJ; PSAN. Category: (G) General (US: Trade). Dimension: 261 x 185 x 27. Weight in Grams: 1198. . 2012. Hardback. . . . . Books ship from the US and Ireland.

Condizione: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if the Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.

HRD. Condizione: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

HRD. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Hardcover. Condizione: new. Hardcover. The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the humandisease.These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated intonovel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments. The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease. These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.

Condizione: new. Questo è un articolo print on demand.

Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The science of autism has seen tremendous breakthroughs in the past few decades. A multitude of relatively rare mutations have been identified to explain around 15 % of autism cases with many of these genetic causes systematically examined in animal models. This marriage of human genetics and basic neurobiology has led to major advances in our understanding of how these genetic mutations alter brain function and help to better understand the human disease.These scientific approaches are leading to the identification of potential therapeutic targets for autism that can be tested in the very same genetic models and hopefully translated into novel, rational therapies. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting theunderlying neurobiology, the book explains, is the key to understanding the pathophysiology of autism and ultimately to identifying novel treatments.

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The Autisms: Molecules to Model Systems provides a roadmap to many of these genetic causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissect.