Isbn: 9786202058360 - formulation of self microemulsifying drug delivery system: smedds of antibiotic (6 risultati)

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Paperback. Condizione: Brand New. 108 pages. 8.58x5.91x0.39 inches. In Stock.

Taschenbuch. Condizione: Neu. Formulation of Self Microemulsifying Drug Delivery System | SMEDDS of Antibiotic | Popat Mohite (u. a.) | Taschenbuch | 108 S. | Englisch | 2017 | LAP LAMBERT Academic Publishing | EAN 9786202058360 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, a method to prepare self-microemulsifying drug delivery system (SMEDDS) of the poorly water-soluble drugcefadroxil monohydrate is explained. The impact of the oil, surfactant and co-surfactant on the drug solubility and their ratios on forming efficient and stable SMEDDS were examined. Water titration method was used to formulation of SMEDDS. The SMEDDS were characterized by morphological observation, globule size, cloud point measurement,viscosity determination,refractive index,% transmittance, drug content of SMEDDS of cefadroxil monohydrate and in vitro release study. The optimum formulation F2 consisted of oleic acid, tween-80 and PEG-400 with S mix. ratio of 1:1. In vitro release test showed a complete release of cefadroxil monohydrate from SMEDDS in an approximately 1.5hr. SMEDDS cefadroxil monohydrate oral formulations were prepared that provide excellent drug solubilization and improved in vitro release of cefadroxil monohydrate compare to marked product. The selected formulation F2 was tested for pharmacokinetic studies in comparison to marketed formulation it showed increase in the oral bioavailability of cefadroxil monohydrate. 108 pp. Englisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In this book, a method to prepare self-microemulsifying drug delivery system (SMEDDS) of the poorly water-soluble drugcefadroxil monohydrate is explained. The impact of the oil, surfactant and co-surfactant on the drug solubility and their ratios on forming efficient and stable SMEDDS were examined. Water titration method was used to formulation of SMEDDS. The SMEDDS were characterized by morphological observation, globule size, cloud point measurement,viscosity determination,refractive index,% transmittance, drug content of SMEDDS of cefadroxil monohydrate and in vitro release study. The optimum formulation F2 consisted of oleic acid, tween-80 and PEG-400 with S mix. ratio of 1:1. In vitro release test showed a complete release of cefadroxil monohydrate from SMEDDS in an approximately 1.5hr. SMEDDS cefadroxil monohydrate oral formulations were prepared that provide excellent drug solubilization and improved in vitro release of cefadroxil monohydrate compare to marked product. The selected formulation F2 was tested for pharmacokinetic studies in comparison to marketed formulation it showed increase in the oral bioavailability of cefadroxil monohydrate.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In this book, a method to prepare self-microemulsifying drug delivery system (SMEDDS) of the poorly water-soluble drugcefadroxil monohydrate is explained. The impact of the oil, surfactant and co-surfactant on the drug solubility and their ratios on forming efficient and stable SMEDDS were examined. Water titration method was used to formulation of SMEDDS. The SMEDDS were characterized by morphological observation, globule size, cloud point measurement,viscosity determination,refractive index,% transmittance, drug content of SMEDDS of cefadroxil monohydrate and in vitro release study. The optimum formulation F2 consisted of oleic acid, tween-80 and PEG-400 with S mix. ratio of 1:1. In vitro release test showed a complete release of cefadroxil monohydrate from SMEDDS in an approximately 1.5hr. SMEDDS cefadroxil monohydrate oral formulations were prepared that provide excellent drug solubilization and improved in vitro release of cefadroxil monohydrate compare to marked product. The selected formulation F2 was tested for pharmacokinetic studies in comparison to marketed formulation it showed increase in the oral bioavailability of cefadroxil monohydrate.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 108 pp. Englisch.…