Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation? 2. Do the cell lines accurately represent the histopathology of the original tumors? 3. Do the cell lines accurately represent the molecular genetics of this type of cancer? The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading.
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Foreword to the Series. Introduction. 1. Sarcomas; B.A. Teicher. 2. Neuroblastoma; C.J. Thiele. 3. Ewing's Sarcoma Family of Tumors; F. van Valen. 4. Malignant Mesothelioma; M.A. Versnel. 5. Pancreatic Tumors; T. Iwamura, M.A. Hollingsworth. 6. Adrenal Cortex; W.E. Rainey, J.J. Mrotek. 7. Thyroid Gland; T. Hoelting. 8. Pituitary Gland; L.J. Hofland, S.W.J. Lamberts. 9. Salivary Gland Tumors; M. Sato. 10. Esophageal Cancers; Y. Shimada. 11. Bladder Cancer; R. Knuechel, J.R.W. Masters. 12. Renal Cell Cancer; T. Ebert, et al. 13. Skin Cancer (Non-Melanoma); P. Boukamp. 14. Melanoma: The Wister Melanoma (WM) Cell Lines; M.-Yu Hau, et al. 15. Melanoma: Brussels Melanoma Cell Lines; F. Brasseur. 16. Melanoma: The Milan Melanoma Cell Lines; A. Anichini, et al.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation 2. Do the cell lines accurately represent the histopathology of the original tumors 3. Do the cell lines accurately represent the molecular genetics of this type of cancer The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading. 308 pp. Englisch. Codice articolo 9789401738248
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes ha. Codice articolo 5837138
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Taschenbuch. Condizione: Neu. Cancer Cell Lines Part 1 | John Masters (u. a.) | Taschenbuch | x | Englisch | 2013 | Springer | EAN 9789401738248 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Codice articolo 105580506
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation 2. Do the cell lines accurately represent the histopathology of the original tumors 3. Do the cell lines accurately represent the molecular genetics of this type of cancer The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 308 pp. Englisch. Codice articolo 9789401738248
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Continuous cell lines derived from human cancers are the most widely used resource in laboratory-based cancer research. The first 3 volumes of this series on Human Cell Culture are devoted to these cancer cell lines. The chapters in these first 3 volumes have a common aim. Their purpose is to address 3 questions of fundamental importance to the relevance of human cancer cell lines as model systems of each type of cancer: 1. Do the cell lines available accurately represent the clinical presentation 2. Do the cell lines accurately represent the histopathology of the original tumors 3. Do the cell lines accurately represent the molecular genetics of this type of cancer The cancer cell lines available are derived, in most cases, from the more aggressive and advanced cancers. There are few cell lines derived from low grade organ-confined cancers. This gap can be filled with conditionally immortalized human cancer cell lines. We do not know why the success rate for establishing cell lines is so low for some types of cancer and so high for others. The histopathology of the tumor of origin and the extent to which the derived cell line retains the differentiated features of that tumor are critical. The concept that a single cell line derived from a tumor at a particular site is representative of tumors at that site is naïve and misleading. Codice articolo 9789401738248
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