Fritz melchers (150 risultati)

gebundene Ausgabe. Condizione: Gut. 340 Seiten; Der Erhaltungszustand des hier angebotenen Werks ist trotz seiner Bibliotheksnutzung sehr sauber. Es befindet sich neben dem Rückenschild lediglich ein Bibliotheksstempel im Buch; ordnungsgemäß entwidmet. In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 780.…

Hardcover. Condizione: Very Good. No Dust Jacket. Library stamps/marks/labels/pocket, otherwise light wear. Solid hardcover.; Current Topics In Microbiology And Immunology; Ex-Library; Vol. 113; 268 pages.

Hardcover. Condizione: UsedVeryGood. Hardcover, with text in German and English; light fading and shelf wear to exterior; former owner's name written on front endpaper; in good condition with clean text, firm binding. ASIN: B001DHJYE2.

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Hardcover. Condizione: Very Good-. No Dust Jacket. Library stamps/marks/labels/pocket, 1" tear to spine edge, otherwise light wear.; Rest of contents of Vol 85: Genetics of immunoresposiveness to natural antigens in the mouse / G. Biozzi . [et al.]; Chemistry and biology of the enterobacterial common antigen / H. Mayer, G. Schmidt; Cumulative Author and Subject Index, Volumes 40-85. ; Current Topics In Microbiology And Immunology, Vol 85; Ex-Library; Vol. 85; 184 pages.…

Hardcover. Condizione: New. No Jacket. 1st Edition. Published by Springer (1999). New Hardcover, no dj. 9.5"x6.1""x0.8". be41552.

Condizione: very_good. Gently read. May have name of previous ownership, or ex-library edition. Binding tight; spine straight and smooth, with no creasing; covers clean and crisp. Minimal signs of handling or shelving. 100% GUARANTEE! Shipped with delivery confirmation, if you're not satisfied with purchase please return item! Ships USPS Media Mail.…

Condizione: Good. *Price HAS BEEN REDUCED by 10% until Monday, Nov. 2 (weekend sale item)* 340 pp., Hardcover, ex library, else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country. Photos available upon request.…

Condizione: Good. *Price HAS BEEN REDUCED by 10% until Monday, Nov. 2 (weekend sale item)* 499 pp., Hardcover, ex library, else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country. Photos available upon request.…

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24 cm XXIII, 246 Seiten. Mit 85 Abbildungen. OKart. Ordnungsgemäß aus einer Universitäts-Bibliothek ausgesondert (Stempel, Signatur). Guter Zustand. Sprache: Englisch Gewicht in Gramm: 516.

Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condizione: Good. *Price HAS BEEN REDUCED by 10% until Monday, Nov. 2 (weekend sale item)* 458 pp., Hardcover, ex library, sticker residue to front cover, half-title page torn at bottom edge, light crease to first 171 pp., else text clean and binding tight. - If you are reading this, this item is actually (physically) in our stock and ready for shipment once ordered. We are not bookjackers. Buyer is responsible for any additional duties, taxes, or fees required by recipient's country. Photos available upon request.…

Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

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Condizione: Used. pp. 224 Index.

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Condizione: Used. pp. 224 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.

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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The 12th Workshop on 'Mechanisms in B-Cell Neoplasia' continues this series of meetings on intriguing new developments in human and experimental B-cell tumors. The integration of knowledge from basic B-cell biology to the clinical problems of multiple myelomas, follicular lymphoma, mantle cell lymphoma and B-CLL present the challenges that were discussed in the meeting. The discussion focusses on:- Cellular components of the 'myeloma clone'- Genomic instability in B-cells and B-cell tumors- The CD5 antigen and B1 cells- Regulation of cell cycle and apoptosis- Role of IL-6, BCL-2, BCL-1, myc in B-cell development.…

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The papers in this book were presented at the 14th Mechanisms in B-cell Neoplasia meeting that was held in Bethesda, Maryland October 21-23, 1996. In 1995 the organizers decided that the format of the meeting would be changed and that specific topics relevant to B-cell neoplasia would be discussed. This year's topic is on the c-myc oncogene in B-cell neoplasia which has been discussed in virtually every previous meeting. Some of the presentations announced for the first time dramatic advances in our understanding of c-myc and because this subject has become highly complex it was thought that devoting the whole meeting to this theme would be appropriate. The book, therefore, repre sents a review of many aspects of the myc problem but by no means is truly comprehensive. In a recent Medline search there were 8,505 references to myc, fully illustrating the magnitude of the interest and depth of this field. The organizers of the meeting have each contributed review chapters that summarize different aspects of the meeting. We thank the National Cancer Institute for sponsoring this workshop and the staff of Cygnus, Inc. , for their outstanding organizational assistance. The organizers are most grateful to Vickie Rogers for assembling the book and dealing with the edi torialization of the manuscripts. MICHAEL POlTER FRITZ MELCHERS Table of Contents M. POlTER and K. B. MARCU The c-myc Story: Where We've Been, Where We Seem to be Going. With 2 Figures . . . . . . . . . . . . . . . . . . . . . . . . I F.…

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The diversity of antigen-binding structures of antibody molecules is so vast that every conceivable antigen can be bound by an antibody molecule within the immune system. This is true even for the antigen binding sites of antibodies called idiotypes, which are bound by complementary bind ing sites of other antibodies called anti-idiotypes. Thus, anti-idiotypes are structural homologues of antigens. These idiotypic-anti-idiotypic interactions constitute a network within the immune system. Since one lymphocyte produces only one type of antibody molecule, this network is in fact a network of cells. We expect that the network is functional: the appearance of antigen will disturb the equilibrium of the network at the point where it competes with the anti idiotypic lymphocyte for binding to the idiotypic lympho cyte. It has been known for quite some time that anti idiotypic antibody can be used to prime the immune system for memory to an antigen that it has never seen. This phe nomenon is now being explored for possible use in immuni zation against viruses, bacteria, parasites and tumors as well as for the modulation of autoimmunity. The ability of anti-idiotypes to mimic, both antigenically and function ally, the corresponding biologically active molecules seen by an idiotypic antibody was first demonstrated for the hormone insulin and is now being observed in many other systems. The papers assembled in this volume bring the reader to the cutting edge of the potential practical applica tions of the network theory of the immune system.…

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The fourth workshop on Mechanisms in B-Ce11 Neoplasia was held in Bethesda. Maryland. at the National Institutes of Health on March 24. 25 and 26. 1986. The meeting was attended by approximately 150 participants and 58 presentations were given. The purpose of these workshops and the yearly publications has been to provide a means for exchanging the rapidly developing information in this field and to bring maJor problems into focus. Edited trans cripts of the 1983 and 1985 workshops were published by Editiones Roche Bas1e, Switzerland. Papers brought to the 1984 workshop were published in Current Topics in Microbiology and Immunology, Vol. 113. Numerous retrovira1 recombinant viral constructs are now in general use in a variety of test systems, both in vivo and in vitro. These are proving to have interesting bio10gica1-prQperties. ------- Kecent1y developed systems for inducing B cell tumors are described: 1) The development of spontaneous ~-ce11 tumors in transgenic mice carrying deregulated ml Pds. genes and the Ig heavy chain promoter; 2) a method for inducing p1asmacytomas in BAL~/c mice with short latent periods of ca 70 days by infecting pristane treated mice with retroviruses carrying various types of deregulated ml Pds. genes; 3) induction of pre-B cell tumors with erbB containing recombinant retroviruses; 4) induction of B-ce11 and other tumors by infection of neonates with recombinant retroviruses. Several retrovira1 constructs containing ml Pds. sequences do not induce B-ce11 tumors in pristane conditioned mice .…

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Main topics covered:B-Cell Development; Immunoglobulin Gene Rearrangement;Multiple Myeloma, Plasmactomas; Lymphomas: B-CLL, Folli-cular Lymphomas BCL-2, BCL-1; Lymphomas: EBV, AIDS Associa-ted Lymphomas; Oncogenes and Transcriptional Factors(text to follow).…

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The humoral response of the immune system to a foreign antigen usually requires the recognition of two antigenic determinants. The one, called the carrier, is recognized by T-Iymphocytes, the other, called the hapten, by B-Iympho cytes. As a consequence, T - and B-Iymphocytes proliferate, B-Iymphocytes produce hapten-specific antibodies, and the system develops memory to the antigens. It was long thought that antigens would form a bridge to mediate the cooperation of T - and B-Iymphocytes. However, it now appears that antigens are broken down to fragments which then act as carrier determinants for T -lymphocytes. The cells which originally process antigen are called an tigen-presenting cells. They have phagocytic properties. They can take up and degrade antigens, in the case of pro teins to peptides. The peptides of protein antigens reappear on the surface of the antigen-presenting cells, where they must become associated with membrane proteins encoded by genes of the major histocompatibility complex (MHC) in order to be recognized by T-Iymphocytes. To activate helper T-Iym phocytes which cooperate in antibody responses, MHC class II molecules have to be expressed on the surface of the antigen-presenting cells. Once T -lymphocytes have be come activated, they are ready to cooperate with B cells. …

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The papers in this book were presented at the 6th Workshop on Mechanisms in B-Cell Neoplasia, held in Bethesda, March 23-25, 1988. On alternate years this meeting is sponsored by the . ; Basel Institute of Immunology in Basel, Switzerland and by the National Cancer Institute in Bethesda, and is attended by 100 to 150 parti cipants. This 6th workshop, like the preceding five, was characterized by intense and enthusiastic discussion which reflects, we think, the exciting growth and development of this field. It is quite clear, however, that despite many general advances an understanding of the precise underlying mechanisms in B-cell tumor development is not yet defined. Probably, there is no single mechanism for all the various forms of B-cell neo plastic development. Many different forms of B-cell neoplasms are known, and these are distinguished by several characteristics: 1) the stage of development attained by the tumor stem cells; 2) mode of growth (slow or fast); 3) association with natural or inductive etiologic agents and 4) specific and consistent mutational mechanisms such as retroviral insertion, chromosomal rearrangement. Those charac teristic forms which arise naturally in relatively high frequency or those tumors with hallmark properties which can be induced consistently are the models most frequently studied, e. g. , endemic Burkitt's lymphoma, follicular lymphoma, acute and chronic lymphocytic leukemia and mUltiple myeloma in man; bursal lymphoma in chickens; Abelson virus induced pre B cell lymphomas and plasmacytomas in mice and immunocytomas in rats. Each model system, has special problems and advantages.…