J lesitha jeeva kumari (10 risultati)

PAP. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

Condizione: New.

Taschenbuch. Condizione: Neu. Study on Prognostic Marker Mucin1 | Molecular Insights in Designing Inhibitor for Breast Cancer Drug Target Mucin1 | J. Lesitha Jeeva Kumari (u. a.) | Taschenbuch | Englisch | 2025 | LAP LAMBERT Academic Publishing | EAN 9783659716423 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 196 pp. Englisch.

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Jesu Jaya Sudan RDr. R. Jesu Jaya Sudan is currently holding the position of Research Coordinator at Marudhar Kesari Jain College for Women, affiliated to Thiruvalluvar University, Tamilnadu, India. He has long standing interest in b.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mucin1 is an important tumor marker, and is notable for the autoproteolytic event, a signature of all SEA domain containing proteins. This work reports an in silico, study of the structural and functional significance of the 18 residue insert in the autoproteolytic process and also the peptide inhibitors for preventing its receptor-ligand alliance. It also reports ligand scaffolds that could effectively participate in inhibition of autoproteolysis of mucin 1. The study reveals both isoforms to poses an intact SEA domain, with an altered functional scaffold around the cleavage site. Mutation analysis by alanine substitutions at the insert region revealed ILE67 to be more destabilizing, resulting in increased fluctuation of the neighboring residues. Furthermore, molecular dynamics simulation revealed Isoleucine67 to contribute more to the structural and functional properties of the protein and therefore is one of the crucial residues for the cleavable nature of MUC1/X. Through virtual screeing and docking two ligand scaffolds were identified that have higher binding affinity towards the cleavage site.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 196 pp. Englisch.…

Condizione: New. Print on Demand.

Condizione: New. Print on Demand.

Condizione: New. PRINT ON DEMAND.