Jucker m (124 risultati)

Paperback. Condizione: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.

Soft cover. Condizione: Very Good. 32 pages. E M Friedwald "Marxism And Science" / Ninetta S Jucker "Italy's Old Trouble" / Peter Fleming "The Role Of Formosa" / Freya Stark "New Year In Mexico" (Papers).

Hardcover. Condizione: Near Fine. No Jacket. 3764366249. Hardcover, light shelf wear. This book was a reference copy in a pharmaceutical company library, and appears unread. 324 pages, index, illustrated with charts, tables and diagrams. Chapters include: Drugs the Human Genome, and Individual Based Medicine; Herbal Medicine of Wisconsin Indians; The Impact of Multiple Drug resistance (MDR) Proteins on Chemotherapy and Drug Discovery; Potassium Channels: Gene Family, Therapeutic Relevance, High-throughput Screening Technologies and Drug Discovery; Dual Serotonin and Noradrenaline Uptake Inhibitor Class of Antidepressants; Advances in QSAR Studies of HIV-1 Reverse Transcriptase Inhibitors. Contents clean, tight and bright. Book.…

Condizione: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has soft covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,700grams, ISBN:9783764365479.

Condizione: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.…

Hardcover. Condizione: Very Good. Hardcover, xxxiii + 543 pages, illustrated, NOT ex-library. A clean copy with unmarked text, free of inscriptions and stamps. Issued without a dust jacket. Contents: Alois Alzheimer [Concerning a unique disease of the cerebral cortex; History of Alzheimer's first case Auguste D; Alzheimer & beginnings of research into Alzheimer's disease; Alzheimer & the myth of the pioneer]; Beginning of modern research [Alzheimer's Disease at mid-Century; Alzheimer's disease research]; Anatomy & Neuropsychology [Anatomical changes underlying dementia in Alzheimer's disease; Staging of cortical neurofibrillary inclusions of the Alzheimer's type; Of stains & brains: how microscopic & clinical observations contributed to the understanding of Alzheimer's disease; Presenile forms of Alzheimer's disease in 2006]; Cholinergic Deficit [Acetylcholine in AD: Expectations meet reality]; Amyloid & Genetics [Discovery of [Beta] Amyloid; Pathways to the discovery of the neuronal origin & proteolytic biogenesis of A[Beta] amyloid of Alzheimer's disease; Amyloid Hypothesis: history & alternatives; Segregation of a missense mutation in the amyloid [Beta]-protein precursor gene with familial Alzheimer's disease; From the amyloid [Beta] protein (A4) to isolation of the first Alzheimer's disease gene: amyloid [Beta] (A4) precursor protein (APP); Commentary on "Correlative memory deficits, A[Beta] elevation & amyloid plaques in transgenic mice"; Vision for the future: pathogenesis, models & experimental therapeutics; PS1, PS2 & APP mutations that cause Alzheimer's disease increase A[Beta]42; Amyloid precursor protein, AD & Down's syndrome; Catabolism of amyloid [Beta] peptide & pathogenesis of sporadic Alzheimer's disease; Synaptic activity, amyloid-[Beta] & AD; Molecular pathogenesis of AD in human peripheral cells: platelets show it all; Neuronal origin hypothesis of cerebral amyloid angiopathy; Neuropathologist & Alzheimer genetics; Genetics, molecular biology & animal modeling of AD; Genetic Alzheimer-frontotemporal dementia spectrum; Mutation of the AD amyloid gene in hereditary cerebral hemorrhage, Dutch type; Physiological generation of Amyloid [Beta]-peptide & its Consequences for AD Research; Activation of [Alpha]-secretase as an approach for treatment of AD; Challenges to the enigma of [gamma]-secretase & to AD; Targeting [gamma]-Secretase; Presenilin/gamma-secretase complex & its potential as a drug target; Identification of [Beta]-secretase]; ApoE [Apolipoprotein E & AD; Apolipoprotein E4: From synaptic remodeling to genetic risk factor in both familial & sporadic AD]; Tau [Alzheimer tangle: 100 years on; Immunological demonstration of tau protein in nearofibrillary tangles; Bulk isolation of neurofibrillary tangles & discoveries of tau & its abnormal hyperphosphorylation; Natural & molecular history of AD; Tau focused drug discovery for AD & related Neurodegenerative Tauopathies; Ubiquitin is a component of paired helical filaments; Influence of tau on neuronal traffic mechanisms; Search for structure of tau & paired helical filaments]; Oxidative Stress [Changing landscape of AD: From Insoluble to Soluble & from Pathogen to Protector; Molecular & cellular pathways towards and away from AD]; Epidemiology [Paquid]; Imaging [Hippocampal imaging in the early diagnosis of AD 1988 to 2006; Detecting Early-Stage AD in MCI & PreMCI; Imaging the pathology of AD: Building on a century-Old blueprint]; Therapeutical Perspectives [How do we test drugs; Inflammation & lesions of AD; A[Beta] immunotherapy prevents & Reverses AD neuropathology; Immunotherapy; "Magic" bullets, shotguns or cocktails to treat or prevent AD?; Seventh age of man: Solving senility]; Forum & Network [Fondation Ipsen & AD: a 20-year relationship; Alzheimer Research Forum: A Knowledge Base and e-Community for AD Research; Potamkin prize for research in Pick's, Alzheimer's and related diseases]; Subject Index.…

Condizione: New.

Paperback or Softback. Condizione: New. Antiviral Agents: Advances and Problems. Book.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

2002th ed. 16 x 23 cm. 332 pages. HC Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Sprache: Englisch.

PF. Condizione: New.

Condizione: New. In English.

Condizione: New. In English.

Condizione: New. In English.

Hardcover. Condizione: Very Good. Hardcover (no jacket) in very good condition. One or two slight bumps and signs of wear to the board edges. A few light marks on the page block. Pages are clean; all text and colour images are clear. CM. Used.

Condizione: New. 978-3-905315-44-8. JUCKER, M. / F. LOETZ, EDS.: TRAVERSE. ZEITSCHRIFT FUER GESCHICHTE, 2 - 2008: DER GEWALTSAME TOD IN DER VORMODERNE / LA MORT VIOLENTE DANS LA PRE MODERNITE . 2008 CHRONOS 320 gr.

Condizione: New. The unfortunate appearance of AIDS, the manifold problems with herpesviruses and other viruses attacking humans have led to an enormous dynamism of worldwide research and to an immense increase in the corresponding literature. This title provides reviews on the development of antiviral agents in some important and widespread viral diseases. Editor(s): Jucker, Ernst. Series: Progress in Drug Research. Num Pages: 266 pages, biography. BIC Classification: MMFM; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 253 x 180 x 15. Weight in Grams: 484. . 2001. 2001st Edition. paperback. . . . .…

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: New. pp. 268.

Condizione: New. pp. 272.

Paperback. Condizione: Brand New. reprint edition. 272 pages. 9.61x6.69x0.57 inches. In Stock.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - In the treatment of infections caused by rapidly mutating viruses like human immunodeficiency virus (HIV), combination therapy with multiple drugs act ing by different mechanisms offers several advantages over monotherapy. It may provide: synergistic effect, possible reduction of dosages and side-effects, and reduction of the chance of drug resistance. In the past few years, hun dreds of HIV protease inhibitors have been synthesized and tested in order to overcome the limitations of reverse transcriptase inhibitors like zidovudine and others. In this review, emphasis is placed on the development of HIV pro tease inhibitors as antiviral agents against HIY, and structure-activity rela tionship analysis of saquinavir and related compounds. Limitations of some protease inhibitors and ways to overcome the shortcomings are presented. Among these many protease inhibitors five have been marketed during 1995-1999. They are saquinavir, ritonavir, indinavir, nelfinavir and ampre navir. Their different structural features, important physicochemical, phar macokinetic and clinical profiles are presented in a table form for easy com parison. It is hoped that in the future new drugs based on additional mech anisms can be developed for the treatment of AIDS. Contents 4 1 Introduction . . HIV protease as a target for chemotherapy . . 2 5 Design of protease inhibitors . . 3 5 Basis of rational design of HIV protease inhibitors . . 3.1 5 New development of HIV protease inhibitors . . 6 3.2 HIV protease inhibitors on the market . . 20 4 20 4.1 SAR of saquinavir and related compounds . .…

Condizione: Used. pp. 352 1st Edition.

Hardcover. Condizione: Very good. Hardcover Octavo no dust jacket. illustrated boards, white lettering, no dust jacket, 543 pp.

Condizione: Used. pp. 352.

Condizione: New. pp. 504 Index.

Condizione: New.