Marion m becker (31 risultati)

- Brossura
Da: Better World Books: West, Reno, NV, U.S.A.Better World Books: West
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Molto buono
EUR 5,97
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Condizione: Very Good. Pages intact with possible writing/highlighting. Binding strong with minor wear. Dust jackets/supplements may not be included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.

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Da: Better World Books: West, Reno, NV, U.S.A.Better World Books: West
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Buono
EUR 5,97
Spedizione gratuitaSpedito in U.S.A.Quantità: 2 disponibili
Condizione: Good. Pages intact with minimal writing/highlighting. The binding may be loose and creased. Dust jackets/supplements are not included. Stock photo provided. Product includes identifying sticker. Better World Books: Buy Books. Do Good.
Lingua: Inglese
Editore: J. M. Dent, 1982
- Rilegato
Da: Redux Books, Grand Rapids, MI, U.S.A.Redux Books
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Buono
EUR 20,64
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Aggiungi al carrelloHardcover. Condizione: Good. Hardcover with dust jacket. Dust jacket is covered with protective mylar, shows edge wear. Previous owner's name on front endpaper. Pages are clean and unmarked. Very slightly foxed. Covers show minor shelf wear. Binding is tight, hinges strong. COVER MAY NOT MATCH THE PICTURE ON THIS SITE.; 100% Satisfaction Guaranteed! Ships same or next business day.…

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Da: Basi6 International, Irving, TX, U.S.A.Basi6 International
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 139,50
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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EUR 165,21
EUR 13,14 spedizioneSpedito da Regno Unito a U.S.A.Quantità: Più di 20 disponibili
Condizione: New. In.

- Brossura
Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 165,21
EUR 13,14 spedizioneSpedito da Regno Unito a U.S.A.Quantità: Più di 20 disponibili
Condizione: New. In.

- Brossura
Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 198,58
EUR 3,44 spedizioneSpedito in U.S.A.Quantità: 4 disponibili
Condizione: New. pp. 285.

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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 210,18
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Condizione: New. pp. 288.
Altre immagini- Brossura
Da: preigu, Osnabrück, Germaniapreigu
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EUR 140,10
EUR 70,00 spedizioneSpedito da Germania a U.S.A.Quantità: 5 disponibili
Taschenbuch. Condizione: Neu. Subtelomeres | Edward J Louis (u. a.) | Taschenbuch | xiv | Englisch | 2016 | Springer | EAN 9783662508022 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

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Da: Buchpark, Trebbin, GermaniaBuchpark
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EUR 122,67
EUR 105,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 288 | Sprache: Englisch | Produktart: Bücher | New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker¿s toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidlyadapt and escape from host immune systems through dynamic changes to the proteins exposed to the host¿s defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.…

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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 234,43
EUR 14,54 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 2 disponibili
Hardcover. Condizione: Brand New. 1st edition. 271 pages. 9.25x6.25x0.75 inches. In Stock.

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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 223,07
EUR 30,50 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker's toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidlyadapt and escape from host immune systems through dynamic changes to the proteins exposed to the host's defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.…

- Rilegato
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 224,71
EUR 30,50 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker's toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidlyadapt and escape from host immune systems through dynamic changes to the proteins exposed to the host's defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.…

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- Edizione Internazionale
Da: UK BOOKS STORE, London, LONDO, Regno UnitoUK BOOKS STORE
Contatta il venditoreVenditore con 5 stelleEdizione InternazionaleCondizione: Nuovo
EUR 266,99
Spedizione gratuitaSpedito da Regno Unito a U.S.A.Quantità: 2 disponibili
Condizione: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if the Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.…

- Brossura
Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 232,43
EUR 34,91 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 2 disponibili
Paperback. Condizione: Brand New. reprint edition. 288 pages. 9.30x6.20x0.68 inches. In Stock.

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Da: Mispah books, Redhill, SURRE, Regno UnitoMispah books
Contatta il venditoreVenditore con 4 stelleCondizione: Usato - Come nuovo
EUR 256,48
EUR 29,09 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

- Brossura
Da: Mispah books, Redhill, SURRE, Regno UnitoMispah books
Contatta il venditoreVenditore con 4 stelleCondizione: Usato - Come nuovo
EUR 275,65
EUR 29,09 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

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Da: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, GermaniaBUCHSERVICE / ANTIQUARIAT Lars Lutzer
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Molto buono
EUR 359,90
EUR 39,95 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Hardcover. Condizione: gut. 2014. Subtelomeres In deutscher Sprache. pages.
Altre immaginiEditore: J. M. Dent & Sons Ltd., London, 1954
- Rilegato
Da: Rooke Books PBFA, Bath, Regno UnitoRooke Books PBFA
Contatta il venditoreVenditore con 5 stelleMembro dell’associazione: PBFA
Condizione: Usato - Molto buono
EUR 83,89
EUR 22,10 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloCloth. Condizione: Very Good. A smart copy of this highly successful guide to cookery from American authors Irma S. Rombauer and her daughter Marion Rombauer Becker. Later edition. First published in 1931 in the US, with the first UK edition in 1945. With a frontispiece. A compilation of reliable recipes with occasional culinary chat, being one of the United States' most-published and one of the world's most widely read cookbooks. Following the loss of her husband, Rombauer's children encouraged her to compile her recipes and thoughts on cooking to help her cope with her loss, creating the first drafts that would later become Joy of Cooking. Containing more than five hundred tested recipes and related commentaries, this work was intended for the homemaker, to provide efficient tips and simple guides. Written by Irma Rombauer, an American cookbook author, best known for this work, and her daughter Marion Rombauer Becker, an American illustrator, author, environmentalist, and arts administrator. Adapted for use in England by M. Baron Russell. In the original full cloth binding. Externally, very smart with light fading to the spine and the odd small mark to the boards. Internally, firmly bound. Pages are very bright with the odd spot. Previous owner's bookplate to the front endpaper with the bookseller's label to the front pastedown. Very Good. None (illustratore). book.…

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- Print on Demand
Da: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 126,26
EUR 11,00 spedizioneSpedito da Italia a U.S.A.Quantità: Più di 20 disponibili
Condizione: new. Questo è un articolo print on demand.

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- Print on Demand
Da: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 126,26
EUR 30,00 spedizioneSpedito da Italia a U.S.A.Quantità: Più di 20 disponibili
Condizione: new. Questo è un articolo print on demand.

- Brossura
- Print on Demand
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker's toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidly adapt and escape from host immune systems through dynamic changes to the proteins exposed to the host's defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective. 288 pp. Englisch.…

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- Print on Demand
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker's toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidly adapt and escape from host immune systems through dynamic changes to the proteins exposed to the host's defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective. 288 pp. Englisch.…

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- Print on Demand
Da: moluna, Greven, Germaniamoluna
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 136,16
EUR 48,99 spedizioneSpedito da Germania a U.S.A.Quantità: Più di 20 disponibili
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a broad introduction to the field of subtelomeresDetailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomesWri. …

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- Print on Demand
Da: moluna, Greven, Germaniamoluna
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 136,16
EUR 48,99 spedizioneSpedito da Germania a U.S.A.Quantità: Più di 20 disponibili
Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a broad introduction to the field of subtelomeresDetailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomesWri. …

- Brossura
- Print on Demand
Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 205,20
EUR 7,56 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 4 disponibili
Condizione: New. Print on Demand pp. 285.

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- Print on Demand
Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 217,15
EUR 7,56 spedizioneSpedito da Regno Unito a U.S.A.Quantità: 4 disponibili
Condizione: New. Print on Demand pp. 288 48 Illus. (19 Col.).

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- Print on Demand
Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios
Contatta il venditoreVenditore con 4 stelleCondizione: Nuovo
EUR 210,35
EUR 9,95 spedizioneSpedito da Germania a U.S.A.Quantità: 4 disponibili
Condizione: New. PRINT ON DEMAND pp. 285.

Lingua: Inglese
Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg Jan 2014, 2014
- Rilegato
- Print on Demand
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker¿s toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidlyadapt and escape from host immune systems through dynamic changes to the proteins exposed to the host¿s defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.…

Lingua: Inglese
Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg Aug 2016, 2016
- Brossura
- Print on Demand
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 160,49
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -New genes and diversity leading to adaptation and evolution are generated in special areas of genomes. One such area in all eukaryotic genomes and in those prokaryotes with linear chromosomes is the region near the ends of the chromosomes. These telomere-associated sequences or subtelomeres, have different properties than the rest of the genome and are one of the most exciting frontiers left in genomics.This book provides a broad introduction to the field of subtelomeres with detailed information from various fields and systems, covering yeasts and fungi, pathogens and parasites, plants, insects, humans and primates and bacteria with linear chromosomes. Advances in the field as well as continuing challenges are discussed throughout. The mosaic nature of this collection and the everchanging perspectives reflect the nature of subtelomeres themselves.Unlike the core of most genomes, which are conserved and stable over time, subtelomeres are dynamic and polymorphic, so much so that generally no two individuals look alike in these regions. The dynamic nature of the region and the ability to change the copy number, generate diversity and try novel combinations make it the evolutionary tinker¿s toolbox. In many organisms the genes found in the region are involved in dealing with the environment. In yeasts, different gene families involved in sugar metabolism as well as clumping together are found in subtelomeres and differences in the region may be the reason why some strains are good for baking, others for brewing and why some are pathogenic. In fungal plant and animal pathogens, many of the genes involved in virulence are found here. In humans and primates there are a number of gene families that vary between ends, for example the diverse olfactory receptor genes. Even in bacterial linear chromosomes the region contains genes involved in adapting to their environments. Perhaps the ultimate use of these regions is in parasites where they rapidlyadapt and escape from host immune systems through dynamic changes to the proteins exposed to the host¿s defenses. Such dynamic, polymorphic structures are also found in plants and insects though it is not always clear what the function might be; in some cases they take on the role of end maintenance. The dynamic, polymorphic nature of subtelomeres, where many ends share segmental duplications, is an exciting area for study but also presents a difficult challenge from the technical perspective.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 288 pp. Englisch.…