springer us apr 2013 (560 risultati)

Taschenbuch. Condizione: Neu. Neuware -Field-programmable logic has been available for a number of years. The role of Field-Programmable Logic Devices (FPLDs) has evolved from simply implementing the system `glue-logic' to the ability to implement very complex system functions, such as microprocessors and microcomputers. The speed with which these devices can be programmed makes them ideal for prototyping. Low production cost makes them competitive for small to medium volume productions. These devices make possible new sophisticated applications, and bring up new hardware/software trade-offs and diminish the traditional hardware/software demarcation line. Advanced design tools are being developed for automatic compilation of complex designs and routings to custom circuits. Digital Systems Design and Prototyping Using Field Programmable Logic covers the subjects of digital systems design and (FPLDs), combining them into an entity useful for designers in the areas of digital systems and rapid system prototyping. It is also useful for the growing community of engineers and researchers dealing with the exciting field of FPLDs, reconfigurable and programmable logic. The authors' goal is to bring these topics to students studying digital system design, computer design, and related subjects in order to show them how very complex circuits can be implemented at the desk. Digital Systems Design and Prototyping Using Field Programmable Logic makes a pioneering effort to present rapid prototyping and generation of computer systems using FPLDs. From the Foreword: `This is a ground-breaking book that bridges the gap between digital design theory and practice. It provides a unifying terminology for describing FPLD technology. In addition to introducing the technology it also describes the design methodology and tools required to harness this technology. It introduces two hardware description languages (e.g. AHDL and VHDL). Design is best learned by practice and the book supports this notion with abundant case studies.' Daniel P. Siewiorek, Carnegie Mellon University CD-ROM INCLUDED! Digital Systems Design and Prototyping Using Field Programmable Logic, First Edition includes a CD-ROM that contains Altera's MAX+PLUS II 7.21 Student Edition Programmable Logic Development Software. MAX+PLUS II is a fully integrated design environment that offers unmatched flexibility and performance. The intuitive graphical interface is complemented by complete and instantly accessible on-line documentation, which makes learning and using MAX+PLUS II quick and easy. The MAX+PLUS II version 7.21 Student Edition offers the following features: Operates on PCs running Windows 3.1, Windows 95 and Windows NT 3.51 and 4.0. Graphical and text-based design entry, including the Altera Hardware Description Language (AHDL) and VHDL. Design compilation for Product-term (MAX 7000S) and look-up table (FLEX 10K) device architectures. Design verification with full timing simulation. 368 pp. Englisch.

Taschenbuch. Condizione: Neu. Neuware -In the strange world of quantum mechanics the application of visualization techniques is particularly rewarding, for it allows us to depict phenomena that cannot be seen by any other means. Visual Quantum Mechanics relies heavily on visualization as a tool for mediating knowledge. The book comes TM with a CD-ROM containing about 320 digital movies in QuickTime f- mat, which can be watched on every multimedia-capable computer. These computer-generated animations are used to introduce, motivate, and ill- trate the concepts of quantum mechanics that are explained in the book. If a picture is worth a thousand words, then my hope is that each short animation (consisting of about a hundred frames) will be worth a hundred thousand words. The collection of lms on the CD-ROM is presented in an interactive en- TM vironmentthathasbeendevelopedwiththehelpofMacromediaDirector . This multimedia presentation can be used like an adventure game without special computer skills. I hope that this presentation format will attract the interest of a wider audience to the beautiful theory of quantum mechanics.

Taschenbuch. Condizione: Neu. Neuware - The aim of the 2nd Course of the International School of Cardi ology at 'Ettore Majorana' was the discussion, scientific analysis, and critical appraisal of primary and secondary prevention in cardi ology, especially concerning the coronary artery disease. The predictive value of different risk factors, the problem of heredity, sociological and psychological perspectives, the impact of antiarrhythmic therapy, and the prevention of sudden death were only some of the many topics discussed. Others, such as physical activity in primary and secondary prevention, the role of coronary bypass surgery in decreasing the mortality rate, the effects of drugs and comprehensive intervention programmes, as well as a critical appraisal of therapy in cardiac failure were given special attention. In organizing this second Course, it was again a privilege and a challenge for the programme directors to conduct a scientific event which, as was demonstrated at the first course, represented an original and new approach to teaching. The illustrious international faculty, composed of well known scientists and experts in their fields, has contributed to the high academic level and quality of the lectures and the following discussions. In our opinion, this successful undertaking would not have achieved its purpose and originality without the beautiful surround ing scenery and tranquility of Erice. We should like to express our gratitude to the director of the Centre, Prof. Zichichi, and the Secretary of 'Ettore Majorana,' Dr.

Taschenbuch. Condizione: Neu. Neuware -Electrothermal Analysis of VLSI Systems addresses electrothermal problems in modern VLSI systems. Part I, The Building Blocks, discusses electrothermal phenomena and the fundamental building blocks that electrothermal simulation requires (including power analysis, temperature-dependent device modeling, thermal/electrothermal simulation, and experimental setup-calibration). Part II, The Applications, discusses three important applications of VLSI electrothermal analysis including temperature-dependent electromigration diagnosis, cell-level thermal placement and temperature-driven power and timing analysis. Electrothermal Analysis of VLSI Systems will be useful for researchers in the fields of IC reliability analysis and physical design, as well as VLSI designers and graduate students. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intrusion Detection In Distributed Systems: An Abstraction-Based Approach presents research contributions in three areas with respect to intrusion detection in distributed systems. The first contribution is an abstraction-based approach to addressing heterogeneity and autonomy of distributed environments. The second contribution is a formal framework for modeling requests among cooperative IDSs and its application to Common Intrusion Detection Framework (CIDF). The third contribution is a novel approach to coordinating different IDSs for distributed event correlation. 160 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -My curiosity and concern about the working class in America stems from childhood memories of my father, a cabinetmaker, and of my oldest brother, an autoworker, who were passionately involved in the labor movement. Perhaps because they so wanted the working class to achieve greater social and economic justice and because they insisted it was not happening, I became curious to know the reasons why. Without even being aware of it, I began to explore a possible explanation-the internal diver sity of the working class. In my studies of autoworkers (the prototype proletarians) in the United States, Italy, Argentina, and India, I discovered that they seemed to be more divided economically, socially, and politically in the more eco nomically advanced countries-an idea that ran contrary to the evolution ary predictions of my Marxist friends. When I reported this in Blue-Collar Stratification (1976), I was surprised that some of them who were commit ted to an ideology of working-class solidarity attacked the hypothesis because it ran against their convictions. 400 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Profound changes were taking place in American society during the period of the 1960s and 1970s when legislation for the National Foundation for the Arts and the Humanities was enacted and the agencies went into operation. It was a period of soul-searching by the American public when the cherished prejudices and civil inequities of the past decades were wiped out and old wounds began to heal; at the same time, however, the Vietnam War was creating new fissures and antagonisms. Into this newly healing, newly questioning society, congressional action thrust the National Council on the Arts in 1964, and the National Endowment for the Arts in 1965. Their mission was to encourage and support the arts, and the men and women charged with this responsibility went about their work with the zeal and enthusiasm of religious converts. The idea of even a minute amount of federal financial assistance to the country's chronically beleaguered and often impoverished artists and arts organi zations seemed strange to a segment of the population that had existed in forgot ten independence from government intervention. Many of the nation's artists and arts leaders were wary, partly because of the uncertainties and constraints of previous patterns of governmental support. 292 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is a collection of extended versions of the papers presented at the Symposium on Next Generation Wireless Networks, May 26, 2000, New Jersey Institute of Technology, Newark, NJ. Each chapter includes, in addition to technical contributions, a tutorial of the corresponding area. It has been a privilege to bring together these contributions from researchers on the leading edge of the field. The papers were submitted in response to a call for papers aiming to concentrate on the applications and services for the 'next generation,' deliberately omitting the numeric reference so that the authors' vision of the future would not be limited by the definitive requirements of a particular set of standards. The book, as a result, reflects the top-down approach by focusing on enabling technologies for the applications and services that are the defining essentials for future wireless networks. This approach strikes a balance between the academia and the industry by addressing new wireless network architectures enabling mobility and location enhanced applications and services that will give wireless systems the competitive edge over others. The main theme of the book is the advent of wireless networks as an irreplaceable means of global communication as opposed to a mere substitute for, or a competitor of, wireline networks. Geolocation emerges as the facilitator of mobility and location sensitive services. The fields of geolocation and wireless communications have been forced to merge, following the Federal Commission of Communications' (FCC) ruling that obliges wireless providers with emergency caller geolocation. 276 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fundamentals of Codes, Graphs, and Iterative Decoding is an explanation of how to introduce local connectivity, and how to exploit simple structural descriptions. Chapter 1 provides an overview of Shannon theory and the basic tools of complexity theory, communication theory, and bounds on code construction. Chapters 2 - 4 provide an overview of 'classical' error control coding, with an introduction to abstract algebra, and block and convolutional codes. Chapters 5 - 9 then proceed to systematically develop the key research results of the 1990s and early 2000s with an introduction to graph theory, followed by chapters on algorithms on graphs, turbo error control, low density parity check codes, and low density generator codes. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In 1978, when the book Living Systems was published, it contained the prediction that the sciences that were concerned with the biological and social sciences would, in the future, be stated as rigorously as the 'hard sciences' that study such nonliving phenomena as temperature, distance, and the interaction of chemical elements. Principles of Quantitative Living Systems Science, the first of a planned series of three books, begins an attempt to fulfill that prediction. The view that living things are similar to other parts of the physical world, differing only in their complexity, was explicitly stated in the early years of the twentieth century by the biologist Ludwig von Bertalanffy. His ideas could not be published until the end of the war in Europe in the 1940s. Von Bertalanffy was strongly opposed to vitalism, the theory current among biologists at the time that life could only be explained by recourse to a 'vital principle' or God. He c- sidered living things to be a part of the natural order, 'systems' like atoms and molecules and planetary systems. Systems were described as being made up of a number of interrelated and interdependent parts, but because of the interrelations, the total system became more than the sum of those parts. These ideas led to the development of systems movements, in both Europe and the United States, that included not only biologists but scientists in other fields as well. Systems societies were formed on both continents. 300 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Welcome to the world of Verilog! Once you read this book, you will join the ranks of the many successful engineers who use Verilog. I have been using Verilog since 1986 and teaching Verilog since 1987. I have seen many different Verilog courses and many approaches to learning Verilog. This book generally follows the outline of the Verilog class that I teach at the University of California, Santa Cruz, Extension. This book does not take a 'cookie-cutter' approach to learning Verilog, nor is it a completely theoretical book. Instead, what we will do is go through some of the formal Verilog syntax and definitions, and then show practical uses. Once we cover most of the constructs of the language, we will look at how style affects the constructs you choose while modeling your design. This is not a complete and exhaustive reference on Verilog. If you want a Verilog reference, I suggest one of the Open Verilog International (OVI) reference manuals. 332 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is now more than 100 years since certain detrimental effects on the ductility of iron were first associated with the presence of hydrogen. Not only is hydrogen embrittlement still a major industri al problem, but it is safe to say that in a mechanistic sense we still do not know what hydrogen (but not nitrogen or oxygen, for example) does on an atomic scale to induce this degradation. The same applies to other examples of environmentally-induced fracture: what is it about the ubiquitous chloride ion that induces premature catastrophic fracture (stress corrosion cracking) of ordinarily ductile austenitic stainless steels Why, moreover, are halide ions troublesome but the nitrate or sulfate anions not deleterious to such stainless steels Likewise, why are some solid metals embrit tled catastrophically by same liquid metals (liquid metal embrit tlement) - copper and aluminum, for example, are embrittled by liquid mercury. In short, despite all that we may know about the materials science and mechanics of fracture on a macroscopic scale, we know little about the atomistics of fracture in the absence of environmental interactions and even less when embrittlement phe nomena such as those described above are involved. On the other hand, it is interesting to note that physical chemists and surface chemists also have interests in the same kinds of interactions that occur on an atomic scale when metals such as nickel or platinum are used, for example, as catalysts for chemical reactions. 1096 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The IFIP TC-10 Working Conference on Distributed and Parallel Embedded Systems (DIPES 2004) brings together experts from industry and academia to discuss recent developments in this important and growing field in the splendid city of Toulouse, France. The ever decreasing price/performance ratio of microcontrollers makes it economically attractive to replace more and more conventional mechanical or electronic control systems within many products by embedded real-time computer systems. An embedded real-time computer system is always part of a well-specified larger system, which we call an intelligent product. Although most intelligent products start out as stand-alone units, many of them are required to interact with other systems at a later stage. At present, many industries are in the middle of this transition from stand-alone products to networked embedded systems. This transition requires reflection and architecting: The complexity of the evolving distributed artifact can only be controlled, if careful planning and principled design methods replace the - hoc engineering of the first version of many standalone embedded products. 340 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Opportunistic, intracellular bacterial infections are in the forefront of research today because of the challenges they present to the immunocompromised patient. In this volume, the pathogenesis and immune reaction of these intracellular infections is featured, as are the most typical problems related to antimicrobial chemotherapy, and current approaches to their solution. Notable chapters set the pace for research on the pathogenic and immune reactions to such infections as Mycobacterium tuberculosis Legionella pneumophila Chlamydia trachomatis and Brucella . 332 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Divided into four parts, this book covers recent developments in topics pertaining to gravity theories, including discussions on the presence of scalar fields. Part One is devoted to exact solutions in general relativity, and is mainly concerned with the results of rotating null dust beams and fluids. Also included is a panoramic vision of new research directions in this area, which would require revising certain theorems and their possible extensions within gravity theories, new aspects concerning the Ernst potentials, double Kerr spacetimes, and rotating configurations. In particular, there is a detailed discussion of totally symmetric and totally geodesic spaces, in which a method for generating (2+1)-dimensional solutions from (3+1)-dimensional solutions is given. Part Two deals with alternative theories of gravity, all of which include scalar fields and gauge fields. Here, quantum and cosmological effects, which arise from both gravity theories in four and higher dimensions and from metric-affine theories, are investigated. Part Three is devoted to cosmological and inflationary scenarios. Local effects, such as the influence of scalar fields in protogalactic interactions, numerical studies of the collapse of molecular cores, as well as the inverse inflationary problem and the blue eigenvalue spectrum of it, are considered. Moreover, the role of scalar fields as dark matter and quantum cosmology in the Bergman-Wagoner and Gowdy theories, together with the relation of the conformal symmetry and deflationary gas universe, are likewise presented. The last part of the book includes some mixed topics which are still in the experimental stage. Among them are the foundation of the Maxwell theory, a discussion on electromagnetic Thirring problems, a note on the staticity of black holes with non-minimally coupled scalar fields, and a study of the Lorentz force free charged fluids in general relativity. Thus, this book is the most up-to-date, comprehensive collection of papers on the subject of exact solutions and scalar fields in gravity and is a valuable tool for researchers in the area. 356 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -stories of postwar nephrology and metabolism. Postwar Uremia is to the nephrologist what the baby is to the nephrology rushed to the fore and supplied nephrologists pediatrician, for it is the final common pathway of literally with such wonderful tools as the flamephotometer, electro hundreds of disease processes that lead to scarring and destruction of nephrons. . phoresis, microchemistry, immunoassay, sonography, renal biopsy, immunofluorescence, electron microscopy, and un We estimate that there are well in excess of 300,000 clear magnetic resonance, and permitted a total integration patients in the world living on the varied methodologies of form, histologic structure, and function. Clinical represented by the three basic forms of substituted kidney nephrology became indeed the real fusion of biochemistry, function-hemodialysis, peritoneal dialysis, and renal physiology, immunology, renal endocrinology, and the transplantation: over 100,000 persons in the United States focus of newer imaging techniques. alone, well over 110,000 in the countries compromising With this precision in diagnosis, one could realistically the EDTA Registry, and over 100,000 in the Pacific Rim. 1336 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Security is probably the most critical factor for the development of the 'Information Society'. E-government, e-commerce, e-healthcare and all other e-activities present challenging security requirements that cannot be satisfied with current technology, except maybe if the citizens accept to waive their privacy, which is unacceptable ethically and socially. New progress is needed in security and privacy-preserving technologies. On these foundations, the IFIP/SEC conference has been established from the eighties as one of the most important forums for presenting new scientific research results as well as best professional practice to improve the security of information systems. This balance between future technology improvements and day-to-day security management has contributed to better understanding between researchers, solution providers and practitioners, making this forum lively and fruitful.Security and Protection in Information Processing Systems contains the papers selected for presentation at the 19th IFIP International Conference on Information Security (SEC2004), which was held in August 2004 as a co-located conference of the 18th IFIP World Computer Congress in Toulouse, France. The conference was sponsored by the International Federation for Information Processing (IFIP).This volume is essential reading for scholars, researchers, and practitioners interested in keeping pace with the ever-growing field of information security. 564 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Faster, better and cheaper are challenges that IT-companies face every day. The customer's expectations shall be met in a world where constant change in environment, organization and technology are the rule rather that the exception. A solution for meeting these challenges is to share knowledge and experience - use the company's own experience, and the experience of other companies. Process Improvement in Practice - A Handbook for IT Companies tackles the problems involved in launching these solutions. Process Improvement in Practice - A Handbook for IT Companies is designed for small IT companies who wish to start with systematic improvement. The methods and techniques in this handbook are tried in practice, and have proven to be easy to use and scalable for local needs. Managers and developers will discover useful tips to initiate improvement work efficiently. This practical handbook is based on the authors' improvement work in a range of companies since the mid-nineties. Process Improvement in Practice - A Handbook for IT Companies is designed for a professional audience, composed of researchers and practitioners in industry. This book is also suitable for graduate-level students in software process improvement and software engineering. 124 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thermodynamic Methods for the Study of Interfacial Regions in Electrochemical Systems.- The Electrode Potential.- The Double Layer in the Absence of Specific Adsorption.- Specific Adsorption of Ions.- Potentials of Zero Charge.- Electric Double Layer on Semiconductor Electrodes.- Insulator/Electolyte Interface.- The Adsorption of Organic Molecules.- The Double Layer in Colloidal Systems. 476 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A NATO Advanced Study Institute on 'Oxygen Radicals in Biological Systems: Recent Progress and New Methods of Study' was held in Braga, Portugal between Sep tember 1 and September 14, 1985, in order to consider the basic chemistry and biochem istry of activated oxygen (both radical and non-radical species) and their effect in biolog ical systems. This book summarizes the main lectures given at this meeting. While there is no attempt to cover all the major topics in the expanding subject of oxidative mechanisms in biology, an effort has been made to provide overviews on some key aspects of this field. The authors have attempted to convey a clear picture of both what is known and what remains unclear in their respective subjects. Not only are some of the techniques used for detecting activated oxygen species described, but also their strengths and limi tations. The chemistry of many of these species is discussed and the biological and/or pathological implications are carefully reviewed. The medical and therapeutic aspects of some of the well established pathways of damage and protection are analyzed. It is our hope that the material included in this book might be useful for both researchers and teachers at the graduate level. The success of this meeting was to a large extent due to the tireless committment of Professor Alberto Amaral and Dr. Concei~a:o Rangel; without their outstanding efforts in dealing with all the aspects of the organization, this summer school would not have been possible. 244 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 18 of the Handbook of Psychopharmacology represents the first of a series of volumes intended to bring earlier sections of the work up to date. Volumes 7, 8, and 9, published in 1977 and 1978, dealt with principles of behavior, drugs and neurotransmitters, and neuroanatomy. In subsequent volumes dedicated to these issues, a mixture of topics will be covered in a given volume, covering both advances in basic knowledge in these three areas of the subject and reviews of theoretical and meth odological issues deemed to be of particular relevance at present. L. L. ! S. D. ! S. H. S. vii CONTENTS CHAPTER 1 Behavior as a Measure of Adverse Responses to Environmental Contaminants BERNARD WEISS 1. Special Perspectives 1 1. 1. Pharmacology and Toxicology . . . . . . . . . . . . . . 1 1. 2. Origins of Behavioral Toxicology . . . . . . . . . . . . 2 1. 3. Special Problems 2 2. Specific Substances . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. 1. Heavy Metals 5 2. 2. Volatile Solvents 20 2. 3. Pesticides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 2. 4. Air Pollutants 36 2. 5. Nonspecific Poisons . . . . . . . . . . . . . . . . . . . . . . 42 2. 6. Food Additives 44 3. Future Prospects 47 3. 1. Chemical Waste . . . . . . . . . . . . . . . . . . . . . . . . . 47 3. 2. Susceptible Populations . . . . 48 3. 3. The Statistics of Risk . . . . . . . . . . . . . . . . . . . . . 49 3. 4. Screening 49 3. 5. Implications for Psychopharmacology 51 4. References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 CHAPTER 2 State Dependent Learning and Drug Discriminations DONALD A. OVERTON 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 2. Description of State Dependent Learning . . . . . . . . . . 59 ix x CONTENTS 3. History of Development of Knowledge about SDL 60 3. 1. Nineteenth Century Reports. . . . . . . . . . . . . . . . 552 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The theme of this volume--risk analysis in the private sector--reflects a changing emphasis in risk analysis. Until re cently, attention has been focused on risk analyses conducted in support of federal regulatory decision making. Such analyses have been used to help set safety standards, to illuminate issues of regulatory concern, and to evaluate regulatory alternatives. As this volume indicates, however, risk analysis encompasses a broader set of activities. Analyses performed by private sector institutions aimed at preventing or reducing potential adverse health or environmental effects also play an important part in societal risk management. In virtually all societies, there have been strong incentives for the private sector to conduct such analyses. These incentives range from moral or altruistic norms and values to simple self-interest based on fear of monetary loss, possible civil or criminal litigation, or punitive or restrictive government action. The papers in this volume address the overall theme from a variety of perspectives. Specifically, the papers represent con tributions from such diverse fields as toxicology, epidemiology, chemistry, biology, engineering, statistics, decision analysis, economics, psychology, philosophy, and the law. 520 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The interest of describing the ground state properties of a system in terms of one electron density (or its two spin components) is obvious, in particular due to the simple physical significance of this function. Recent experimental progress in diffraction made the measurement of charge and magnetization densities in crystalline solids possible, with an accuracy at least as good as theoretical accuracy. Theoretical developments of the many-body problem have proved the extreme importance of the one electron density function and presently, accurate methods of band structure determination become available. Parallel to the diffraction techniques, other domains of research (inelastic scattering, resonance, molecular spectroscopy) deal with quantities directly related to the one particle density. But the two types of studies do not interfere enough and one should obviously gain more information by interpreting all experiments that are related to the density together. It became necessary to have an International School that reviews the status of the art in the domain of 'ELECTRON AND MAGNETIZATION DENSITIES IN MOLECULES AND CRYSTALS'. This was made possible through the generous effort of N.A.T.O. 's Scientific Affairs Division, and I would specially thank Dr. T. KESTER, the head of this Division, for his help and competence. An Advanced Study Institute was thus held in ARLES, south France, from the 16th to the 31st of August 1978. 924 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is based on the proceedings of a NATO-Gulbenkian Foundation sponsored Summer School held in May-June 1982 in Sintra Estoril, Portugal. Given the accelerated growth of knowledge in the field of eukaryotic gene expression, it seemed timely to hold a NATO Advanced Study Institute to discuss current developments in this area of biology and to evaluate the potential of emerging technologies such as gene transfer, recombinant DNA cloning and quantitative high resolution two-dimensional gel electrophoresis. The initial articles in t~is volume describe various differentiation models and address questions such as the relationships between differentiation and cell proliferation, biochemical changes accompanying differen tiation, expression of differentiated gene products and their regulation as well as gene organization of cytoskeletal proteins. The second section describes properties of neoplastic cells, surveys current assays for transformation and offers some new insights into the mechanisms involved in carcinogenesis. The third part is dedicated to viral oncogenesis and to the role of onco genes in cell transformation. Particular emphasis is given to the role of tyrosine kinases in cell transformation. The concluding section deals with various aspects of gene expression in normal and transformed cells with special emphasis given to studies using two dimensional gel electrophoresis, cell hybridization, gene transfer and immunological techniques. 456 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Structure and Organization of the ras Gene Family, in Human.- Transcriptional Regulatory Sequences in the H-ras1 Gene.- Mutational Activation of Human ras Genes.- Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment.- Ras Mutations in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy.- High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours.- Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers.- Human Thyroid Neoplasms Express ras p21 Protein at High Levels.- Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse.- Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors.- DNA Methylation of the Human Hras1 Gene.- Structure of the Drosophila ras2 Bidirectional Promoter.- The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells.- Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase.- The Function of the Mammalian ras Proteins.- Ras Proteins as Potential Activators of Protein Kinase C Function.- Novel Phosphorylation of ras p21 and Mutational Studies.- The Role of p21ras in Proliferative Signal Transduction.- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System.- Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene.- Regulation of Cell Death by ras and myc Oncogenes.- Ras-Induced Phenotypic Changes in Human Fibroblasts.- Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides.- Expression of ras, myc and fos Oncogenes During the DMSO-Induced Detransformation of a Colon Carcinoma Line (HT29).- The ras Oncogene and Myogenic Commitment and Differentiation.- Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc.- Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro.- Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction.- Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins.- Molecular Interactions of p21.- Ras-Transformed Cells Contain Microtubules Rich in Modified -Tubulin in Their Trailing Edges.- Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins.- Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene.- -Adrenoceptor is Required for Activation of Avian Erythrocyte GS by Guanine Nucleotides.- Expression of ras Oncogene in Xenopus laevis.- An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21.- Identification of a Protein Interacting with ras-p21- by Chemical Cross-Linking.- Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins.- Structural Investigations on the G-Binding Domain of p21.- Molecular Biology of GAP and its Interaction with Oncogenic ras p21.- The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells. 336 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is meant as a present to honor Professor on the th occasion of his 70 birthday. It collects refereed contributions from sixty-one mathematicians from eleven countries. They cover many different areas of research related to the work of Professor including Navier-Stokes equations, nonlinear elasticity, non-Newtonian fluids, regularity of solutions of parabolic and elliptic problems, operator theory and numerical methods. The realization of this book could not have been made possible without the generous support of Centro de Matemática Aplicada (CMA/IST) and Fundação Calouste Gulbenkian. Special thanks are due to Dr. Ulrych for the careful preparation of the final version of this book. Last but not least, we wish to express our gratitude to Dr. for her invaluable assistance from the very beginning. This project could not have been successfully concluded without her enthusiasm and loving care for her father. On behalf of the editors ADÉLIA SEQUEIRA v honored by the Order of Merit of the Czech Republic by Václav Havel, President of the Czech Republic, on the October 28, 1998, Professor Emeritus of Mathematics at the Charles University in Prague, Presidential Research Professor at the Northern Illinois University and Doctor Honoris Causa at the Technical University of Dresden, has been enriching the Czech and world mathematics with his new ideas in the areas of partial differential equations, nonlinear functional analysis and applications of the both disciplines in continuum mechanics and hydrodynamics for more than forty years. 580 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the proceedings of the EMBO-NATO-CEC Advanced Research Workshop on 'Guanine-nucleotide binding proteins. Common structural and functional properties', which was held in Renesse, The Netherlands, August 6-11, 1988. The transmission of information is one of the most important processes in cellular life and involves the most diverse physiological functions. The cellular membrane, as the obligatory target for external signals, harbours complex pathways transducing the signals from the receptors of the external stimuli to the cytoplasmic effector. Heterotrimeric proteins are fundamental components of these pathways. Other proteins that are monomeric may be found associated with the membrane or in soluble form in the cytoplasm, and' can also function in signal transduction. Intracellular transmission of signals may proceed in an analogous fashion, protein synthesis being a well-known example. It is one of the most remarkable and puzzling observations of recent years that all of these proteins share common properties, both functionally and structurally. The ir primary structures show pronounced s imilari ties, in most cases concentrated in the NH2-terminal portion of the molecule. They all bind guanine nucleotides (hence the general name of G-proteins) and are GTPases, a crucial enzymatic activity, since it converts the active complex induced by GTP into the inactive one induced by GDP. Consensus sequences have been ident if ied as responsable for interact ing with the different parts of the guanine nucleotide. 420 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A unified approach is proposed for applied mechanics and optimal control theory. The Hamilton system methodology in analytical mechanics is used for eigenvalue problems, vibration theory, gyroscopic systems, structural mechanics, wave-guide, LQ control, Kalman filter, robust control etc. All aspects are described in the same unified methodology. Numerical methods for all these problems are provided and given in meta-language, which can be implemented easily on the computer. Precise integration methods both for initial value problems and for two-point boundary value problems are proposed, which result in the numerical solutions of computer precision. Key Features of the text include: -Unified approach based on Hamilton duality system theory and symplectic mathematics. -Gyroscopic system vibration, eigenvalue problems. -Canonical transformation applied to non-linear systems. -Pseudo-excitation method for structural random vibrations. -Precise integration of two-point boundary value problems. -Wave propagation along wave-guides, scattering. -Precise solution of Riccati differential equations. -Kalman filtering. -HINFINITY theory of control and filter. 472 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -On June 24-26, 1985, a major International Conference on the Hea1th Effects of P01yunsaturated Fatty Acids in Seafoods was held in Washington, D. C. The conference had two objectives: (1) to review the research data on the health effects of polyunsaturated fatty acids in seafoods in terms of the impact of omega-3 fatty acids on eicosanoid formation, thrombosis and inflammation, and the role of docosahexaenoic acid in membrane function and metabolism, and (2) to develop a research agenda to determine the spectrum of the health effects of polyunsaturated fatty acids of seafood origin in the American diet. The 1985 conference established the fact that omega-3 fatty acids of marine origin - eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) - play important roles in prostaglandin metabolism, thrombosis and atherosc1erosis, immunology and inflammation, and membrane function. In response to the conference recommendations, the Congress of the United States provided special funding for the establishment of a 'test materials 1aboratory' within the US Department of Commerce to produce under documented quality contr01 the types and quanti ties of omega-3 te~3t materials required by biomedica1 researchers. The forms of test materials to be produced include refined fish oil, polyunsaturated fatty acid enhanced triglycerides, concentrates of esters of fatty acids, purified omega-3 fatty acids, and omega-3 mono-, di- and tri~lyceride mixtures. 468 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Artificial Intelligence and Innovations (AIAI) will interest researchers, IT professionals and consultants by examining technologies and applications of demonstrable value. The conference focused on profitable intelligent systems and technologies.AIAI focuses on real world applications; therefore authors should highlight the benefits of AI technology for industry and services. Novel approaches solving business and industrial problems, using AI, will emerge from this conference. 500 pp. Englisch.